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Dextromoramide (Palfium, Palphium, Jetrium, Dimorlin) is a powerful opioid analgesic approximately three times more potent than morphine but shorter acting. It is subject to drug prohibition regimes, both internationally through UN treaties and by the criminal law of individual nations, and is usually prescribed only in the Netherlands.
The analysis highlights History, Applications and Measurement as prominent areas in the source structure around Dextromoramide.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
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The extracted context around Dextromoramide shows recurring relationship patterns in the source. For example, Dextromoramide → Although, Australia, Dependence, Janssen Pharmaceuticals, Palfium, Paul Janssen, UK, United Kingdom Another extracted example is Dextromoramide → AU: S8 (Controlled drug), BR: Class A1 (Narcotic drugs), CA: Schedule I, DE: Anlage II (Authorized trade only, not prescriptible), US: Schedule I. Use these groups to spot repeated connection types before inspecting the individual relationships.
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palfium drug use potent drugs opioid analgesic racemoramide netherlands molecule oral controlled name also used series pyrrolidine morphine 3d isomer
TTTA extracted 42 structured relationships around Dextromoramide. Examples in this analysis include Dextromoramide → 3D model (JSmol) → Interactive image and Dextromoramide → AHFS/Drugs.com → International Drug Names. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Dextromoramide | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Dextromoramide | AHFS/Drugs.com | International Drug Names | 1.00 | infobox |
| Dextromoramide | ATC code | N02AC01 (WHO) | 1.00 | infobox |
| Dextromoramide | Bioavailability | >75% | 1.00 | infobox |
| Dextromoramide | CAS Number | 357-56-2 N | 1.00 | infobox |
| Dextromoramide | ChEBI | CHEBI:74274 N | 1.00 | infobox |
| Dextromoramide | ChEMBL | ChEMBL431928 N | 1.00 | infobox |
| Dextromoramide | ChemSpider | 83901 Y | 1.00 | infobox |
| Dextromoramide | CompTox Dashboard (EPA) | DTXSID8022909 | 1.00 | infobox |
| Dextromoramide | DrugBank | DB01529 Y | 1.00 | infobox |
| Dextromoramide | ECHA InfoCard | 100.006.013 | 1.00 | infobox |
| Dextromoramide | Elimination half-life | 3.5 hours | 1.00 | infobox |
| Dextromoramide | Excretion | Urine, faeces | 1.00 | infobox |
| Dextromoramide | Formula | C25H32N2O2 | 1.00 | infobox |
| Dextromoramide | KEGG | D07287 Y | 1.00 | infobox |
| Dextromoramide | Legal status | AU: S8 (Controlled drug) | 1.00 | infobox |
| Dextromoramide | Legal status | BR: Class A1 (Narcotic drugs) | 1.00 | infobox |
| Dextromoramide | Legal status | CA: Schedule I | 1.00 | infobox |
| Dextromoramide | Legal status | DE: Anlage II (Authorized trade only, not prescriptible) | 1.00 | infobox |
| Dextromoramide | Legal status | US: Schedule I | 1.00 | infobox |
| Dextromoramide | Metabolism | Liver, partly mediated by CYP3A4 | 1.00 | infobox |
| Dextromoramide | Molar mass | 392.543 g·mol−1 | 1.00 | infobox |
| Dextromoramide | Pregnancy category | AU: C | 1.00 | infobox |
| Dextromoramide | Protein binding | High | 1.00 | infobox |
| Dextromoramide | PubChem CID | 92943 | 1.00 | infobox |
| Dextromoramide | Routes of administration | Oral, Rectal, Intravenous, Insufflation | 1.00 | infobox |
| Dextromoramide | Trade names | Palfium | 1.00 | infobox |
| Dextromoramide | UNII | 9S4S6CIY83 | 1.00 | infobox |
The concept neighborhoods around Dextromoramide bring nearby vocabulary together. In this analysis, examples include Potent, Palfium and Use. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Dextromoramide, one of the stronger structural bridges in this analysis connects Dextromoramide with History. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Dextromoramide to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications & Measurement, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Dextromoramide · EN edition · Analysis: TopicsToTalkAbout