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Dextromoramide

Dextromoramide (Palfium, Palphium, Jetrium, Dimorlin) is a powerful opioid analgesic approximately three times more potent than morphine but shorter acting. It is subject to drug prohibition regimes, both internationally through UN treaties and by the criminal law of individual nations, and is usually prescribed only in the Netherlands.

History, Applications & Measurement

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History

Paul JanssenJanssen PharmaceuticalsFentanylHaloperidolPiritramide
13 related topics

Medical use

ConstipationCancer pain
2 related topics

Chemistry

IsomerLevomoramide
2 related topics

Overview

OpioidAnalgesicDrug prohibitionNetherlands
4 related topics

Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
International Drug Names
ATC code
N02AC01 (WHO)
Bioavailability
>75%
CAS Number
357-56-2 N
ChEBI
CHEBI:74274 N

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Overview

History

Medical use

Chemistry

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Map overview Semantic statistics

Dextromoramide

Nodes26
Edges25
Triples47
Avg. degree1.92
Density0.076923
Components1

How this topic connects Entity context

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Dextromoramide

Top relations

related to history · 9
Dextromoramide → Although, Australia, Dependence, It, Janssen Pharmaceuticals, Palfium, Paul Janssen, UK, United Kingdom
related to Chemistry · 6
Dextromoramide → C25H32N2O2, Diphenyl-γ-Dialkyamino-Butyramides, Its, Methyl-4-morpholino-2, Other, The
Legal status · 5
Dextromoramide → AU: S8 (Controlled drug), BR: Class A1 (Narcotic drugs), CA: Schedule I, DE: Anlage II (Authorized trade only, not prescriptible), US: Schedule I
related to Pharmacokinetics · 4
Dextromoramide → L/kg, Less, Peak, While
3D model (JSmol) · 1
Dextromoramide → Interactive image
AHFS/Drugs.com · 1
Dextromoramide → International Drug Names
ATC code · 1
Dextromoramide → N02AC01 (WHO)
Bioavailability · 1
Dextromoramide → 75%
CAS Number · 1
Dextromoramide → 357-56-2 N
ChEBI · 1
Dextromoramide → CHEBI:74274 N

Important terminology Word statistics

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Important terminology

palfium drug use potent drugs opioid analgesic racemoramide netherlands molecule oral controlled name also used series pyrrolidine morphine 3d isomer

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Dextromoramide3D model (JSmol)Interactive image1.00infobox
DextromoramideAHFS/Drugs.comInternational Drug Names1.00infobox
DextromoramideATC codeN02AC01 (WHO)1.00infobox
DextromoramideBioavailability>75%1.00infobox
DextromoramideCAS Number357-56-2 N1.00infobox
DextromoramideChEBICHEBI:74274 N1.00infobox
DextromoramideChEMBLChEMBL431928 N1.00infobox
DextromoramideChemSpider83901 Y1.00infobox
DextromoramideCompTox Dashboard (EPA)DTXSID80229091.00infobox
DextromoramideDrugBankDB01529 Y1.00infobox
DextromoramideECHA InfoCard100.006.0131.00infobox
DextromoramideElimination half-life3.5 hours1.00infobox
DextromoramideExcretionUrine, faeces1.00infobox
DextromoramideFormulaC25H32N2O21.00infobox
DextromoramideKEGGD07287 Y1.00infobox
DextromoramideLegal statusAU: S8 (Controlled drug)1.00infobox
DextromoramideLegal statusBR: Class A1 (Narcotic drugs)1.00infobox
DextromoramideLegal statusCA: Schedule I1.00infobox
DextromoramideLegal statusDE: Anlage II (Authorized trade only, not prescriptible)1.00infobox
DextromoramideLegal statusUS: Schedule I1.00infobox
DextromoramideMetabolismLiver, partly mediated by CYP3A41.00infobox
DextromoramideMolar mass392.543 g·mol−11.00infobox
DextromoramidePregnancy categoryAU: C1.00infobox
DextromoramideProtein bindingHigh1.00infobox
DextromoramidePubChem CID929431.00infobox
DextromoramideRoutes of administrationOral, Rectal, Intravenous, Insufflation1.00infobox
DextromoramideTrade namesPalfium1.00infobox
DextromoramideUNII9S4S6CIY831.00infobox

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