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A protecting group or protective group is introduced into a molecule by chemical modification of a functional group to obtain chemoselectivity in a subsequent chemical reaction. It plays an important role in multistep organic synthesis.
Applications, Orthogonal protection & Common protecting groups
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groups protecting acid group synthesis removed ethers acetals carbonyl esters also cleavage used base acetal ether common conditions reaction protected
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Protecting group | is a | protected protecting group | 0.90 | text |
| reaction time | instance of | The protecting groups in solid-phase synthesis regarding the reaction conditions | 0.80 | text |
| temperature | instance of | The protecting groups in solid-phase synthesis regarding the reaction conditions | 0.80 | text |
| reagents can be standardized so that they are carried out by a machine | instance of | The protecting groups in solid-phase synthesis regarding the reaction conditions | 0.80 | text |
| while yields of well over 99 | instance of | The protecting groups in solid-phase synthesis regarding the reaction conditions | 0.80 | text |
| Protecting group | has application | Although | 0.60 | section |
| Protecting group | has application | Roche | 0.60 | section |
| Protecting group | has application | Tamiflu | 0.60 | section |
| Protecting group | has application | An | 0.60 | section |
| Protecting group | has application | Vitamin | 0.60 | section |
| Protecting group | has application | Reichstein | 0.60 | section |
| Protecting group | related to 1,2-Diols | The | 0.60 | section |
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