DEFA5

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Export map as:

Research this topic

Explore the main themes, entities and connections around DEFA5. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Function

C. difficile TcdA TcdB Bacterial wall

4 related topics

Structure

Disulfide bridges Cysteine Intestinal lumen

3 related topics

Gene and tissue distribution

Alpha defensin Chromosome 8 Paneth cells

3 related topics

Overview

Protein Gene Paneth cells Ileum Defensins

6 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: DEFA5, DEF5, HD-5, defensin alpha 5, alpha defensin 5
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZMP, 2LXZ, 2MIT, 3I5W, 4E82, 4E83, 4E86, 4RBW, 4RBX, 5CUM, 5CUJ, 5CUI
Band: 8p23.1 · 8 A2|8
Bgee: duodenum · gonad · testicle · appendix · gastric mucosa
BioGPS: More reference expression data
Chr.: Chromosome 8 (human) · Chromosome 8 (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Structure

Gene and tissue distribution

Function

C. difficile Clostridioides difficile (bacteria)
TcdA Clostridium difficile toxin A
TcdB Clostridium difficile toxin B
Bacterial wall

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes21

Edges20

Triples89

Avg. degree1.9

Density0.095238

Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

DEFA5

Top relations

Gene ontology · 21

DEFA5 → antibacterial humoral response, antimicrobial humoral immune response mediated by antimicrobial peptide, antimicrobial humoral response, cellular response to lipopolysaccharide, cytoplasmic vesicle, defense response, defense response to bacterium, defense response to fungus, defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, extracellular region, extracellular space, Golgi lumen, innate immune response, innate immune response in mucosa, killing of cells of other organism, membrane disruption in other organism, positive regulation of membrane permeability, protein homodimerization activity, secretory granule lumen

Bgee · 19

DEFA5 → appendix, blood, colon, duodenum, embryo, esophagus, gastric mucosa, gonad, ileum, jejunum, liver, lymph node, pancreas, rectum, right lung, stomach, testicle, thymus, transverse colon

RNA expression pattern · 19

DEFA5 → appendix, blood, colon, duodenum, embryo, esophagus, gastric mucosa, gonad, ileum, jejunum, liver, lymph node, pancreas, rectum, right lung, stomach, testicle, thymus, transverse colon

related to Function · 6

DEFA5 → CDT, CDTb, Clostridioides, In, TcdA, TcdB

Band · 2

DEFA5 → 8 A2|8, 8p23.1

Chr. · 2

DEFA5 → Chromosome 8 (human), Chromosome 8 (mouse)

End · 2

DEFA5 → 21,556,012 bp, 7,056,739 bp

Aliases · 1

DEFA5 → DEFA5, DEF5, HD-5, defensin alpha 5, alpha defensin 5

Available structures · 1

DEFA5 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZMP, 2LXZ, 2MIT, 3I5W, 4E82, 4E83, 4E86, 4RBW, 4RBX, 5CUM, 5CUJ, 5CUI

BioGPS · 1

DEFA5 → More reference expression data

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human gene bp chr band chromosome protein defensin cells ileum alpha expressed antimicrobial location function bacterial amp microbiota mouse defense

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
DEFA5	Aliases	DEFA5, DEF5, HD-5, defensin alpha 5, alpha defensin 5	1.00	infobox
DEFA5	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1ZMP, 2LXZ, 2MIT, 3I5W, 4E82, 4E83, 4E86, 4RBW, 4RBX, 5CUM, 5CUJ, 5CUI	1.00	infobox
DEFA5	Band	8p23.1	1.00	infobox
DEFA5	Band	8 A2\|8	1.00	infobox
DEFA5	Bgee	duodenum	1.00	infobox
DEFA5	Bgee	gonad	1.00	infobox
DEFA5	Bgee	testicle	1.00	infobox
DEFA5	Bgee	appendix	1.00	infobox
DEFA5	Bgee	gastric mucosa	1.00	infobox
DEFA5	Bgee	right lung	1.00	infobox
DEFA5	Bgee	transverse colon	1.00	infobox
DEFA5	Bgee	lymph node	1.00	infobox
DEFA5	Bgee	rectum	1.00	infobox
DEFA5	Bgee	blood	1.00	infobox
DEFA5	Bgee	ileum	1.00	infobox
DEFA5	Bgee	jejunum	1.00	infobox
DEFA5	Bgee	embryo	1.00	infobox
DEFA5	Bgee	colon	1.00	infobox
DEFA5	Bgee	pancreas	1.00	infobox
DEFA5	Bgee	thymus	1.00	infobox
DEFA5	Bgee	esophagus	1.00	infobox
DEFA5	Bgee	liver	1.00	infobox
DEFA5	Bgee	stomach	1.00	infobox
DEFA5	BioGPS	More reference expression data	1.00	infobox
DEFA5	Chr.	Chromosome 8 (human)	1.00	infobox
DEFA5	Chr.	Chromosome 8 (mouse)	1.00	infobox
DEFA5	Databases	NCBI: entry; OMA: entry	1.00	infobox
DEFA5	End	7,056,739 bp	1.00	infobox
DEFA5	End	21,556,012 bp	1.00	infobox
DEFA5	Ensembl	ENSG00000164816 ENSG00000285251	1.00	infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

Connections between topic areas Semantic bridges

Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

Min side: 3