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Creatinase

In enzymology, creatinase (EC 3.5.3.3), also known as creatine amidinohydrolase, is classified as a hydrolase enzyme, acting on carbon-nitrogen bonds in linear amidines. Specifically, this enzyme breaks the amidino C-N bond in creatine, producing sarcosine and urea. Creatinase activity has been described in several bacteria species, most notably…

Products, Organisms and discovery & Structure

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Organisms and discovery

BacillusFlavobacteriumMicrococcusAlcaligenesClostridium
10 related topics

Structure

HomodimericMolecular massMonomerHydrogen bondsIon pairs
9 related topics

Reaction pathway

CatalyzesChemical reactionH2OZn2+Mn2+
6 related topics

Importance in metabolism

Creatinine
1 related topics

Key facts & relationships

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BRENDA
enzyme data
CAS no.
37340-58-2
EC no.
3.5.3.3
ExPASy
NiceZyme view
Gene Ontology
AmiGO / QuickGO
KEGG
enzyme entry

Topics to explore

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Overview

Organisms and discovery

Structure

Reaction pathway

Importance in metabolism

Advanced semantic analysis

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Map overview Semantic statistics

Creatinase

Nodes42
Edges41
Triples54
Avg. degree1.95
Density0.047619
Components1

How this topic connects Entity context

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Creatinase

Top relations

related to Organisms and discovery · 18
Creatinase → Alcaligenes, AraC/GAT-R, Arthrobacter, Bacillus, CahR, Clostridium, Escherichia, Expression, Flavobacterium, Girard, In, It, Lacombe, Micrococcus, Paracoccus, Pseudomonas, Roche, This
related to Reaction pathway · 11
Creatinase → CH, CH2CO2H, CH3, CH3N, CN, CO, H2N, H2O, HN, NH, NH2
related to Importance in metabolism · 7
Creatinase → ADP, Animal, ATP, For, In, The, To
related to Structure · 3
Creatinase → Da, Each, The
related to Domains · 2
Creatinase → C-terminal, N-terminal
BRENDA · 1
Creatinase → enzyme data
CAS no. · 1
Creatinase → 37340-58-2
EC no. · 1
Creatinase → 3.5.3.3
ExPASy · 1
Creatinase → NiceZyme view
Gene Ontology · 1
Creatinase → AmiGO / QuickGO

Important terminology Word statistics

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Important terminology

enzyme creatine described ion domains bonds amidino pseudomonas c-n bond gene nitrogen carbon two putida monomer product metabolism structures sarcosine

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CreatinaseBRENDAenzyme data1.00infobox
CreatinaseCAS no.37340-58-21.00infobox
CreatinaseEC no.3.5.3.31.00infobox
CreatinaseExPASyNiceZyme view1.00infobox
CreatinaseGene OntologyAmiGO / QuickGO1.00infobox
CreatinaseKEGGenzyme entry1.00infobox
CreatinaseMetaCycmetabolic pathway1.00infobox
CreatinaseNCBIproteins1.00infobox
CreatinasePDB structuresRCSB PDB PDBe PDBsum1.00infobox
CreatinasePMCarticles1.00infobox
CreatinasePubMedarticles1.00infobox
CreatinaseRheareactions1.00infobox
CreatinaseSearchSearchPMCarticlesPubMedarticlesNCBIproteins1.00infobox

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    Min side: 3
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