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CORO1A: Measurement, Function & Discovery

Coronin-1A is a protein that in humans is encoded by the CORO1A gene. It has been implicated in both T-cell mediated immunity and mitochondrial apoptosis. In a recent genome-wide longevity study, its expression levels were found to be negatively associated both with age at the time of blood sample and the survival time after blood draw.

Language: English [EN]
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CORO1A topic overview

The analysis highlights Measurement, Function and Discovery as prominent areas in the source structure around CORO1A.

Related topics
7
Source areas
3
Connected nodes
10
Extracted relationships
126
Concept neighborhoods
7
Bridge connections
10

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 3 topics
Overview · 3 topics
Discovery · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CORO1A, CLABP, CLIPINA, HCORO1, IMD8, TACO, p57, coronin 1A
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2AKF, 2AQ5, 2B4E
Band
16p11.2 · 7 69.25 cM|7 F3
Bgee
granulocyte · monocyte · blood · spleen · appendix
BioGPS
More reference expression data
Chr.
Chromosome 16 (human) · Chromosome 7 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Discovery

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CORO1A connects Entity context

The extracted context around CORO1A shows recurring relationship patterns in the source. For example, CORO1A → actin binding, actin cytoskeleton, actin cytoskeleton organization, actin filament, actin filament binding, actin filament organization, actin monomer binding, axon, calcium ion transport, cell cortex, cell leading edge, cell migration, cell-cell junction, cell-substrate adhesion, cellular response to interleukin-4, cortical actin cytoskeleton, cytoplasm, cytoplasmic vesicle, cytoskeletal protein binding, cytoskeleton Another extracted example is CORO1A → appendix, blood, bone marrow, bone marrow cell, dentate gyrus of hippocampal formation granule cell, granulocyte, lymph node, mesenteric lymph nodes, monocyte, prefrontal cortex, right lung lobe, spleen, thymus, tibiofemoral joint, trabecular bone. Use these groups to spot repeated connection types before inspecting the individual relationships.

CORO1A

Top relations

Gene ontology · 61
CORO1A → actin binding, actin cytoskeleton, actin cytoskeleton organization, actin filament, actin filament binding, actin filament organization, actin monomer binding, axon, calcium ion transport, cell cortex, cell leading edge, cell migration, cell-cell junction, cell-substrate adhesion, cellular response to interleukin-4, cortical actin cytoskeleton, cytoplasm, cytoplasmic vesicle, cytoskeletal protein binding, cytoskeleton
Bgee · 15
CORO1A → appendix, blood, bone marrow, bone marrow cell, dentate gyrus of hippocampal formation granule cell, granulocyte, lymph node, mesenteric lymph nodes, monocyte, prefrontal cortex, right lung lobe, spleen, thymus, tibiofemoral joint, trabecular bone
RNA expression pattern · 15
CORO1A → appendix, blood, bone marrow, bone marrow cell, dentate gyrus of hippocampal formation granule cell, granulocyte, lymph node, mesenteric lymph nodes, monocyte, prefrontal cortex, right lung lobe, spleen, thymus, tibiofemoral joint, trabecular bone
related to External links · 8
CORO1A → Coronin-1A, Human CORO1A, O89053, Overview, PDB, PDBe-KB, UCSC Genome Browser, UniProt
related to Phylogeny · 4
CORO1A → Coronin, Coronin-1a, CRN4, The
Band · 2
CORO1A → 16p11.2, 7 69.25 cM|7 F3
Chr. · 2
CORO1A → Chromosome 16 (human), Chromosome 7 (mouse)
End · 2
CORO1A → 126,306,959 bp, 30,189,076 bp
Aliases · 1
CORO1A → CORO1A, CLABP, CLIPINA, HCORO1, IMD8, TACO, p57, coronin 1A
Available structures · 1
CORO1A → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2AKF, 2AQ5, 2B4E

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

coronin-1a protein coronin bp structure human gene cell chr band actin chromosome 16 location proteins binding cytoskeletal process expression blood

CORO1A relationships Subject–Predicate–Object triples

TTTA extracted 126 structured relationships around CORO1A. Examples in this analysis include CORO1A → Aliases → CORO1A, CLABP, CLIPINA, HCORO1, IMD8, TACO, p57, coronin 1A and CORO1A → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2AKF, 2AQ5, 2B4E. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CORO1AAliasesCORO1A, CLABP, CLIPINA, HCORO1, IMD8, TACO, p57, coronin 1A1.00infobox
CORO1AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2AKF, 2AQ5, 2B4E1.00infobox
CORO1ABand16p11.21.00infobox
CORO1ABand7 69.25 cM|7 F31.00infobox
CORO1ABgeegranulocyte1.00infobox
CORO1ABgeemonocyte1.00infobox
CORO1ABgeeblood1.00infobox
CORO1ABgeespleen1.00infobox
CORO1ABgeeappendix1.00infobox
CORO1ABgeebone marrow1.00infobox
CORO1ABgeebone marrow cell1.00infobox
CORO1ABgeelymph node1.00infobox
CORO1ABgeetrabecular bone1.00infobox
CORO1ABgeethymus1.00infobox
CORO1ABgeemesenteric lymph nodes1.00infobox
CORO1ABgeetibiofemoral joint1.00infobox
CORO1ABgeeright lung lobe1.00infobox
CORO1ABgeedentate gyrus of hippocampal formation granule cell1.00infobox
CORO1ABgeeprefrontal cortex1.00infobox
CORO1ABioGPSMore reference expression data1.00infobox
CORO1AChr.Chromosome 16 (human)1.00infobox
CORO1AChr.Chromosome 7 (mouse)1.00infobox
CORO1ADatabasesNCBI: entry; OMA: entry1.00infobox
CORO1AEnd30,189,076 bp1.00infobox
CORO1AEnd126,306,959 bp1.00infobox
CORO1AEnsemblENSG000001028791.00infobox
CORO1AEntrez111511.00infobox
CORO1AExternal IDsOMIM: 605000; MGI: 1345961; GeneCards: CORO1A1.00infobox
CORO1AGene location (Human)Gene location (Human)Chr.Chromosome 16 (human)Band16p11.2Start30,182,827 bpEnd30,189,076 bp1.00infobox
CORO1AGene location (Mouse)Gene location (Mouse)Chr.Chromosome 7 (mouse)Band7 69.25 cM|7 F3Start126,298,945 bpEnd126,306,959 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around CORO1A bring nearby vocabulary together. In this analysis, examples include Gene, Location and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • CORO1A
    • Gene
    • Location
    • Human
    • Function
    • Chromosome
    • Coronin
    • Bp
    • Chr
    • External
    • Protein
    • Cytoplasm
    • Mouse
  • coro1a
    • Gene
    • Location
    • Human
    • Function
    • Chromosome
    • Coronin
    • Bp
    • Chr
    • External
    • Protein
    • Cytoplasm
    • Mouse
  • gene
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Function
    • Mouse
    • Band
    • External
    • Protein
    • Coronin
    • Cytoplasm
  • cell cortex
    • Cytoplasm
    • Cortex
    • Process
    • Function
    • Fusion
    • Mouse
    • O89053
    • Uniprot
    • Coronin-1a
    • Binding
    • Cytoskeletal
    • Expression
  • function
    • Chromosome
    • External
    • Location
    • Bp
    • Chr
    • Gene
    • Human
    • Cytoplasm
    • Mouse
    • O89053
    • Pdb
    • Uniprot
  • cytoplasm
    • Function
    • Mouse
    • O89053
    • Uniprot
    • Expression
    • Family
    • Fusion
    • View
    • Cytoskeletal
    • Location
    • Process
    • Gene
  • protein
    • View
    • O89053
    • Uniprot
    • Beta
    • Propeller
    • Secondary
    • Seven
    • Structure

Connections between topic areas Semantic bridges

For CORO1A, one of the stronger structural bridges in this analysis connects CORO1A with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CORO1AOverview · splits 7 ⟂ 4
CORO1AFunction · splits 7 ⟂ 4

Map overview Semantic statistics

CORO1A

Nodes11
Edges10
Triples126
Avg. degree1.82
Density0.181818
Components1

Source & methodology

TTTA analyzes the structure around CORO1A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Function & Discovery, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CORO1A · EN edition · Analysis: TopicsToTalkAbout

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