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Coronin-1A is a protein that in humans is encoded by the CORO1A gene. It has been implicated in both T-cell mediated immunity and mitochondrial apoptosis. In a recent genome-wide longevity study, its expression levels were found to be negatively associated both with age at the time of blood sample and the survival time after blood draw.
The analysis highlights Measurement, Function and Discovery as prominent areas in the source structure around CORO1A.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around CORO1A shows recurring relationship patterns in the source. For example, CORO1A → actin binding, actin cytoskeleton, actin cytoskeleton organization, actin filament, actin filament binding, actin filament organization, actin monomer binding, axon, calcium ion transport, cell cortex, cell leading edge, cell migration, cell-cell junction, cell-substrate adhesion, cellular response to interleukin-4, cortical actin cytoskeleton, cytoplasm, cytoplasmic vesicle, cytoskeletal protein binding, cytoskeleton Another extracted example is CORO1A → appendix, blood, bone marrow, bone marrow cell, dentate gyrus of hippocampal formation granule cell, granulocyte, lymph node, mesenteric lymph nodes, monocyte, prefrontal cortex, right lung lobe, spleen, thymus, tibiofemoral joint, trabecular bone. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
coronin-1a protein coronin bp structure human gene cell chr band actin chromosome 16 location proteins binding cytoskeletal process expression blood
TTTA extracted 126 structured relationships around CORO1A. Examples in this analysis include CORO1A → Aliases → CORO1A, CLABP, CLIPINA, HCORO1, IMD8, TACO, p57, coronin 1A and CORO1A → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2AKF, 2AQ5, 2B4E. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| CORO1A | Aliases | CORO1A, CLABP, CLIPINA, HCORO1, IMD8, TACO, p57, coronin 1A | 1.00 | infobox |
| CORO1A | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2AKF, 2AQ5, 2B4E | 1.00 | infobox |
| CORO1A | Band | 16p11.2 | 1.00 | infobox |
| CORO1A | Band | 7 69.25 cM|7 F3 | 1.00 | infobox |
| CORO1A | Bgee | granulocyte | 1.00 | infobox |
| CORO1A | Bgee | monocyte | 1.00 | infobox |
| CORO1A | Bgee | blood | 1.00 | infobox |
| CORO1A | Bgee | spleen | 1.00 | infobox |
| CORO1A | Bgee | appendix | 1.00 | infobox |
| CORO1A | Bgee | bone marrow | 1.00 | infobox |
| CORO1A | Bgee | bone marrow cell | 1.00 | infobox |
| CORO1A | Bgee | lymph node | 1.00 | infobox |
| CORO1A | Bgee | trabecular bone | 1.00 | infobox |
| CORO1A | Bgee | thymus | 1.00 | infobox |
| CORO1A | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| CORO1A | Bgee | tibiofemoral joint | 1.00 | infobox |
| CORO1A | Bgee | right lung lobe | 1.00 | infobox |
| CORO1A | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| CORO1A | Bgee | prefrontal cortex | 1.00 | infobox |
| CORO1A | BioGPS | More reference expression data | 1.00 | infobox |
| CORO1A | Chr. | Chromosome 16 (human) | 1.00 | infobox |
| CORO1A | Chr. | Chromosome 7 (mouse) | 1.00 | infobox |
| CORO1A | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| CORO1A | End | 30,189,076 bp | 1.00 | infobox |
| CORO1A | End | 126,306,959 bp | 1.00 | infobox |
| CORO1A | Ensembl | ENSG00000102879 | 1.00 | infobox |
| CORO1A | Entrez | 11151 | 1.00 | infobox |
| CORO1A | External IDs | OMIM: 605000; MGI: 1345961; GeneCards: CORO1A | 1.00 | infobox |
| CORO1A | Gene location (Human) | Gene location (Human)Chr.Chromosome 16 (human)Band16p11.2Start30,182,827 bpEnd30,189,076 bp | 1.00 | infobox |
| CORO1A | Gene location (Mouse) | Gene location (Mouse)Chr.Chromosome 7 (mouse)Band7 69.25 cM|7 F3Start126,298,945 bpEnd126,306,959 bp | 1.00 | infobox |
The concept neighborhoods around CORO1A bring nearby vocabulary together. In this analysis, examples include Gene, Location and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For CORO1A, one of the stronger structural bridges in this analysis connects CORO1A with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around CORO1A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Function & Discovery, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — CORO1A · EN edition · Analysis: TopicsToTalkAbout