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CORO1A

Coronin-1A is a protein that in humans is encoded by the CORO1A gene. It has been implicated in both T-cell mediated immunity and mitochondrial apoptosis. In a recent genome-wide longevity study, its expression levels were found to be negatively associated both with age at the time of blood sample and the survival time after blood draw.

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Function

Cell cortexCytoplasmCalcineurin
3 related topics

Discovery

Complementary DNA
1 related topics

Overview

ProteinGeneApoptosis
3 related topics

Key facts & relationships

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Aliases
CORO1A, CLABP, CLIPINA, HCORO1, IMD8, TACO, p57, coronin 1A
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2AKF, 2AQ5, 2B4E
Band
16p11.2 · 7 69.25 cM|7 F3
Bgee
granulocyte · monocyte · blood · spleen · appendix
BioGPS
More reference expression data
Chr.
Chromosome 16 (human) · Chromosome 7 (mouse)

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Map overview Semantic statistics

CORO1A

Nodes11
Edges10
Triples126
Avg. degree1.82
Density0.181818
Components1

How this topic connects Entity context

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CORO1A

Top relations

Gene ontology · 61
CORO1A → actin binding, actin cytoskeleton, actin cytoskeleton organization, actin filament, actin filament binding, actin filament organization, actin monomer binding, axon, calcium ion transport, cell cortex, cell leading edge, cell migration, cell-cell junction, cell-substrate adhesion, cellular response to interleukin-4, cortical actin cytoskeleton, cytoplasm, cytoplasmic vesicle, cytoskeletal protein binding, cytoskeleton
Bgee · 15
CORO1A → appendix, blood, bone marrow, bone marrow cell, dentate gyrus of hippocampal formation granule cell, granulocyte, lymph node, mesenteric lymph nodes, monocyte, prefrontal cortex, right lung lobe, spleen, thymus, tibiofemoral joint, trabecular bone
RNA expression pattern · 15
CORO1A → appendix, blood, bone marrow, bone marrow cell, dentate gyrus of hippocampal formation granule cell, granulocyte, lymph node, mesenteric lymph nodes, monocyte, prefrontal cortex, right lung lobe, spleen, thymus, tibiofemoral joint, trabecular bone
related to External links · 8
CORO1A → Coronin-1A, Human CORO1A, O89053, Overview, PDB, PDBe-KB, UCSC Genome Browser, UniProt
related to Phylogeny · 4
CORO1A → Coronin, Coronin-1a, CRN4, The
Band · 2
CORO1A → 16p11.2, 7 69.25 cM|7 F3
Chr. · 2
CORO1A → Chromosome 16 (human), Chromosome 7 (mouse)
End · 2
CORO1A → 126,306,959 bp, 30,189,076 bp
Aliases · 1
CORO1A → CORO1A, CLABP, CLIPINA, HCORO1, IMD8, TACO, p57, coronin 1A
Available structures · 1
CORO1A → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2AKF, 2AQ5, 2B4E

Important terminology Word statistics

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Important terminology

coronin-1a protein coronin bp structure human gene cell chr band actin chromosome 16 location proteins binding cytoskeletal process expression blood

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CORO1AAliasesCORO1A, CLABP, CLIPINA, HCORO1, IMD8, TACO, p57, coronin 1A1.00infobox
CORO1AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2AKF, 2AQ5, 2B4E1.00infobox
CORO1ABand16p11.21.00infobox
CORO1ABand7 69.25 cM|7 F31.00infobox
CORO1ABgeegranulocyte1.00infobox
CORO1ABgeemonocyte1.00infobox
CORO1ABgeeblood1.00infobox
CORO1ABgeespleen1.00infobox
CORO1ABgeeappendix1.00infobox
CORO1ABgeebone marrow1.00infobox
CORO1ABgeebone marrow cell1.00infobox
CORO1ABgeelymph node1.00infobox
CORO1ABgeetrabecular bone1.00infobox
CORO1ABgeethymus1.00infobox
CORO1ABgeemesenteric lymph nodes1.00infobox
CORO1ABgeetibiofemoral joint1.00infobox
CORO1ABgeeright lung lobe1.00infobox
CORO1ABgeedentate gyrus of hippocampal formation granule cell1.00infobox
CORO1ABgeeprefrontal cortex1.00infobox
CORO1ABioGPSMore reference expression data1.00infobox
CORO1AChr.Chromosome 16 (human)1.00infobox
CORO1AChr.Chromosome 7 (mouse)1.00infobox
CORO1ADatabasesNCBI: entry; OMA: entry1.00infobox
CORO1AEnd30,189,076 bp1.00infobox
CORO1AEnd126,306,959 bp1.00infobox
CORO1AEnsemblENSG000001028791.00infobox
CORO1AEntrez111511.00infobox
CORO1AExternal IDsOMIM: 605000; MGI: 1345961; GeneCards: CORO1A1.00infobox
CORO1AGene location (Human)Gene location (Human)Chr.Chromosome 16 (human)Band16p11.2Start30,182,827 bpEnd30,189,076 bp1.00infobox
CORO1AGene location (Mouse)Gene location (Mouse)Chr.Chromosome 7 (mouse)Band7 69.25 cM|7 F3Start126,298,945 bpEnd126,306,959 bp1.00infobox

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