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Complement factor B: Regions, Function & Overview

Complement factor B is a protein that in humans is encoded by the CFB gene.

Language: English [EN]
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Complement factor B topic overview

The analysis highlights Regions, Function and Overview as prominent areas in the source structure around Complement factor B.

Related topics
8
Source areas
2
Connected nodes
10
Extracted relationships
103
Concept neighborhoods
9
Bridge connections
10

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 6 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3.4.21.47
Aliases
CFB, Cfb, AI195813, AI255840, Bf, C2, Fb, H2-Bf, AHUS4, ARMD14, BFD, CFAB, CFBD, FBI12, GBG, PBF2, complement factor B
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3HS0, 1DLE, 1Q0P, 1RRK, 1RS0, 1RTK, 2OK5, 2WIN, 2XWB, 2XWJ, 3HRZ
Band
6p21.33 · 17 B1|17 18.41 cM
Bgee
right lobe of liver · gallbladder · appendix · duodenum · islet of Langerhans
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Complement factor B connects Entity context

The extracted context around Complement factor B shows recurring relationship patterns in the source. For example, Complement factor B → appendix, colon, Descending thoracic aorta, duodenum, gallbladder, gastric mucosa, hepatobiliary system, human kidney, ileum, islet of Langerhans, jejunum, liver, olfactory zone of nasal mucosa, proximal tubule, right coronary artery, right kidney, right lobe of liver, white adipose tissue Another extracted example is Complement factor B → blood microparticle, complement activation, complement activation, alternative pathway, complement binding, extracellular exosome, extracellular region, extracellular space, hydrolase activity, immune system process, innate immune response, peptidase activity, plasma membrane, protein binding, proteolysis, regulation of complement activation, serine-type endopeptidase activity, serine-type peptidase activity. Use these groups to spot repeated connection types before inspecting the individual relationships.

Complement factor B

Top relations

Bgee · 18
Complement factor B → appendix, colon, Descending thoracic aorta, duodenum, gallbladder, gastric mucosa, hepatobiliary system, human kidney, ileum, islet of Langerhans, jejunum, liver, olfactory zone of nasal mucosa, proximal tubule, right coronary artery, right kidney, right lobe of liver, white adipose tissue
RNA expression pattern · 18
Complement factor B → appendix, colon, Descending thoracic aorta, duodenum, gallbladder, gastric mucosa, hepatobiliary system, human kidney, ileum, islet of Langerhans, jejunum, liver, olfactory zone of nasal mucosa, proximal tubule, right coronary artery, right kidney, right lobe of liver, white adipose tissue
Gene ontology · 17
Complement factor B → blood microparticle, complement activation, complement activation, alternative pathway, complement binding, extracellular exosome, extracellular region, extracellular space, hydrolase activity, immune system process, innate immune response, peptidase activity, plasma membrane, protein binding, proteolysis, regulation of complement activation, serine-type endopeptidase activity, serine-type peptidase activity
related to External links · 14
Complement factor B → Atypical Hemolytic-Uremic SyndromeOMIM, Atypical Hemolytic-Uremic SyndromeThe MEROPS, Complement, Factor, GeneReviews/NCBI/NIH/UW, Medicine Medical Subject Headings, MeSH, National Library, Overview, P00751, PDB, PDBe-KB, S01, UniProt
related to Function · 10
Complement factor B → Ba, Bb, C3, C3b, Factor, III, MHC, The, This, Upon
Band · 2
Complement factor B → 17 B1|17 18.41 cM, 6p21.33
Chr. · 2
Complement factor B → Chromosome 17 (mouse), Chromosome 6 (human)
End · 2
Complement factor B → 31,952,084 bp, 35,081,494 bp
3.4.21.47 · 1
Complement factor B → ↗
Aliases · 1
Complement factor B → CFB, Cfb, AI195813, AI255840, Bf, C2, Fb, H2-Bf, AHUS4, ARMD14, BFD, CFAB, CFBD, FBI12, GBG, PBF2, complement factor B

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

complement bp gene factor chr human band chromosome cfb alternative pathway location end protein mouse activation component function external pdb

Complement factor B relationships Subject–Predicate–Object triples

TTTA extracted 103 structured relationships around Complement factor B. Examples in this analysis include Complement factor B → 3.4.21.47 → ↗ and Complement factor B → Aliases → CFB, Cfb, AI195813, AI255840, Bf, C2, Fb, H2-Bf, AHUS4, ARMD14, BFD, CFAB, CFBD, FBI12, GBG, PBF2, complement factor B. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Complement factor B3.4.21.471.00infobox
Complement factor BAliasesCFB, Cfb, AI195813, AI255840, Bf, C2, Fb, H2-Bf, AHUS4, ARMD14, BFD, CFAB, CFBD, FBI12, GBG, PBF2, complement factor B1.00infobox
Complement factor BAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3HS0, 1DLE, 1Q0P, 1RRK, 1RS0, 1RTK, 2OK5, 2WIN, 2XWB, 2XWJ, 3HRZ1.00infobox
Complement factor BBand6p21.331.00infobox
Complement factor BBand17 B1|17 18.41 cM1.00infobox
Complement factor BBgeeright lobe of liver1.00infobox
Complement factor BBgeegallbladder1.00infobox
Complement factor BBgeeappendix1.00infobox
Complement factor BBgeeduodenum1.00infobox
Complement factor BBgeeislet of Langerhans1.00infobox
Complement factor BBgeeolfactory zone of nasal mucosa1.00infobox
Complement factor BBgeeDescending thoracic aorta1.00infobox
Complement factor BBgeegastric mucosa1.00infobox
Complement factor BBgeeright coronary artery1.00infobox
Complement factor BBgeehuman kidney1.00infobox
Complement factor BBgeeproximal tubule1.00infobox
Complement factor BBgeeright kidney1.00infobox
Complement factor BBgeewhite adipose tissue1.00infobox
Complement factor BBgeehepatobiliary system1.00infobox
Complement factor BBgeeliver1.00infobox
Complement factor BBgeejejunum1.00infobox
Complement factor BBgeeileum1.00infobox
Complement factor BBgeecolon1.00infobox
Complement factor BBioGPSMore reference expression data1.00infobox
Complement factor BChr.Chromosome 6 (human)1.00infobox
Complement factor BChr.Chromosome 17 (mouse)1.00infobox
Complement factor BDatabasesNCBI: entry; OMA: entry1.00infobox
Complement factor BEnd31,952,084 bp1.00infobox
Complement factor BEnd35,081,494 bp1.00infobox
Complement factor BEnsemblENSG00000243570 ENSG00000239754 ENSG00000243649 ENSG00000241253 ENSG00000242335 ENSG00000241534 ENSG000002043591.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Complement factor B bring nearby vocabulary together. In this analysis, examples include Factor, Gene and Cfb. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Complement factor B
    • Factor
    • Gene
    • Cfb
    • Bp
    • Activation
    • Activity
    • Available
    • Blood
    • Component
    • Entry
    • Function
    • Ncbi
  • complement factor b
    • Factor
    • Gene
    • Cfb
    • Bp
    • Activation
    • Activity
    • Available
    • Blood
    • Component
    • Entry
    • Function
    • Ncbi
  • gene
    • Chromosome
    • Bp
    • End
    • Location
    • Human
    • Chr
    • Activity
    • B1
    • Component
    • Function
    • Mouse
    • Protein
  • alternative pathway
    • Pathway
    • Bb
    • B1
    • Blood
    • Complement
    • Component
    • Entry
    • Factor
    • Function
    • Mouse
    • Ncbi
    • P00751
  • complement
    • Factor
    • Gene
    • Cfb
    • Bp
    • Activation
    • Activity
    • Available
    • Component
    • Entry
    • Function
    • Ncbi
    • Omim
  • factor d
    • Gene
    • Activation
    • Activity
    • Available
    • Blood
    • Entry
    • Function
    • Ncbi
    • Omim
    • P00751
    • Pdb
    • Protein
  • chromosome 6
    • Human
    • Location
    • Bp
    • Gene
    • Band
    • B1
    • Function
    • Mouse
    • Region
    • Search
    • End
    • Complement
  • function
    • Activity
    • Search
    • Location
    • Human
    • Chr
    • Chromosome
    • Activation
    • Available
    • B1
    • Blood
    • Bp
    • Component

Connections between topic areas Semantic bridges

For Complement factor B, one of the stronger structural bridges in this analysis connects Complement factor B with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Complement factor BFunction · splits 4 ⟂ 7
Complement factor BOverview · splits 8 ⟂ 3

Map overview Semantic statistics

Complement factor B

Nodes11
Edges10
Triples103
Avg. degree1.82
Density0.181818
Components1

Source & methodology

TTTA analyzes the structure around Complement factor B to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Complement factor B · EN edition · Analysis: TopicsToTalkAbout

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