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Complement component 9

Complement component 9 (C9) is a MACPF protein involved in the complement system, which is part of the innate immune system. Once activated, about 12-18 molecules of C9 polymerize to form pores in target cell membranes, causing lysis and cell death. C9 is one member of the complement membrane attack complex (MAC), which also includes complement…

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Aliases
C9, ARMD15, C9D, complement component 9, complement C9
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5FMW
Band
5p13.1 · 15|15 A1
Bgee
right lobe of liver · testicle · gonad · buccal mucosa cell · human kidney
BioGPS
n/a
Chr.
Chromosome 5 (human) · Chromosome 15 (mouse)

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Complement component 9

Nodes17
Edges16
Triples83
Avg. degree1.88
Density0.117647
Components1

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Complement component 9

Top relations

Gene ontology · 22
Complement component 9 → blood microparticle, cell killing, complement activation, alternative pathway, complement activation, classical pathway, cytolysis, cytosol, extracellular exosome, extracellular region, extracellular space, growth factor activity, hemolysis by symbiont of host erythrocytes, immune response, immune system process, innate immune response, integral component of membrane, integral component of plasma membrane, membrane, membrane attack complex, other organism cell membrane, plasma membrane
Bgee · 19
Complement component 9 → blastocyst, buccal mucosa cell, corpus epididymis, embryo, gallbladder, gonad, human kidney, left lobe of liver, migratory enteric neural crest cell, olfactory epithelium, precursor cell, right adrenal cortex, right adrenal gland, right coronary artery, right lobe of liver, stromal cell of endometrium, testicle, thoracic diaphragm, yolk sac
RNA expression pattern · 19
Complement component 9 → blastocyst, buccal mucosa cell, corpus epididymis, embryo, gallbladder, gonad, human kidney, left lobe of liver, migratory enteric neural crest cell, olfactory epithelium, precursor cell, right adrenal cortex, right adrenal gland, right coronary artery, right lobe of liver, stromal cell of endometrium, testicle, thoracic diaphragm, yolk sac
Band · 2
Complement component 9 → 15|15 A1, 5p13.1
Chr. · 2
Complement component 9 → Chromosome 15 (mouse), Chromosome 5 (human)
End · 2
Complement component 9 → 39,371,324 bp, 6,528,232 bp
Aliases · 1
Complement component 9 → C9, ARMD15, C9D, complement component 9, complement C9
Available structures · 1
Complement component 9 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5FMW
BioGPS · 1
Complement component 9 → n/a
Databases · 1
Complement component 9 → NCBI: entry; OMA: entry

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Important terminology

c9 complement bp human formation chr band mac cell component target chromosome complex molecules protein membrane pore gene location pores

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Complement component 9AliasesC9, ARMD15, C9D, complement component 9, complement C91.00infobox
Complement component 9Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5FMW1.00infobox
Complement component 9Band5p13.11.00infobox
Complement component 9Band15|15 A11.00infobox
Complement component 9Bgeeright lobe of liver1.00infobox
Complement component 9Bgeetesticle1.00infobox
Complement component 9Bgeegonad1.00infobox
Complement component 9Bgeebuccal mucosa cell1.00infobox
Complement component 9Bgeehuman kidney1.00infobox
Complement component 9Bgeecorpus epididymis1.00infobox
Complement component 9Bgeestromal cell of endometrium1.00infobox
Complement component 9Bgeeright adrenal gland1.00infobox
Complement component 9Bgeeright adrenal cortex1.00infobox
Complement component 9Bgeeright coronary artery1.00infobox
Complement component 9Bgeeleft lobe of liver1.00infobox
Complement component 9Bgeegallbladder1.00infobox
Complement component 9Bgeeolfactory epithelium1.00infobox
Complement component 9Bgeeembryo1.00infobox
Complement component 9Bgeeblastocyst1.00infobox
Complement component 9Bgeeyolk sac1.00infobox
Complement component 9Bgeeprecursor cell1.00infobox
Complement component 9Bgeemigratory enteric neural crest cell1.00infobox
Complement component 9Bgeethoracic diaphragm1.00infobox
Complement component 9BioGPSn/a1.00infobox
Complement component 9Chr.Chromosome 5 (human)1.00infobox
Complement component 9Chr.Chromosome 15 (mouse)1.00infobox
Complement component 9DatabasesNCBI: entry; OMA: entry1.00infobox
Complement component 9End39,371,324 bp1.00infobox
Complement component 9End6,528,232 bp1.00infobox
Complement component 9EnsemblENSG000001136001.00infobox

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