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Codon usage bias refers to differences in the frequency of occurrence of synonymous codons in coding DNA. A codon is a series of three nucleotides (a triplet) that encodes a specific amino acid residue in a polypeptide chain or for the termination of translation (stop codons).
Products, Consequences of codon composition & Evolutionary theories
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codon codons usage translation gene organisms trna bias selection amino protein expression genes folding optimization biases acid different genetic rates
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| local mRNA folding | instance of | new strategies for optimization of heterologous expression consider global nucleotide content | 0.80 | text |
| codon pair bias | instance of | new strategies for optimization of heterologous expression consider global nucleotide content | 0.80 | text |
| a codon ramp | instance of | new strategies for optimization of heterologous expression consider global nucleotide content | 0.80 | text |
| codon harmonization or codon correlations | instance of | new strategies for optimization of heterologous expression consider global nucleotide content | 0.80 | text |
| those involved in amino acid starvation | instance of | artificial gene synthesis is often necessary for the creation of such an optimized gene.Specialized codon bias is further seen in some endogenous genes | 0.80 | text |
| Codon usage bias | related to Contributing factors | Different | 0.60 | section |
| Codon usage bias | related to Contributing factors | GC | 0.60 | section |
| Codon usage bias | related to Contributing factors | RNA | 0.60 | section |
| Codon usage bias | related to External links | Composition Analysis Toolkit Archived | 0.60 | section |
| Codon usage bias | related to External links | Wayback Machine | 0.60 | section |
| Codon usage bias | related to External links | Codon Usage Table | 0.60 | section |
| Codon usage bias | related to External links | Usage DatabaseCodonWGraphical Codon Usage | 0.60 | section |
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