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CLCN3: Interactions & Overview

2Cl-/H+ exchanger 3 is a protein that in humans is encoded by the CLCN3 gene.

Language: English [EN]
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CLCN3 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around CLCN3.

Related topics
5
Source areas
2
Connected nodes
7
Extracted relationships
106
Related term clusters
5
Bridge connections
7

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 3 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CLCN3, CLC3, ClC-3, chloride voltage-gated channel 3, NEDSBA, NEDHYBA
Band
4q33 · 8 B3.1|8 30.9 cM
Bgee
mucosa of sigmoid colon · endothelial cell · Brodmann area 46 · Epithelium of choroid plexus · retinal pigment epithelium
BioGPS
More reference expression data
Chr.
Chromosome 4 (human) · Chromosome 8 (mouse)
Databases
NCBI: entry; OMA: entry

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CLCN3
5Protein · Gene · Protein-protein interaction

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How CLCN3 connects Entity context

The extracted context around CLCN3 shows recurring relationship patterns in the source. For example, CLCN3 → antiporter activity, ATP binding, cell surface, chloride channel activity, chloride ion binding, chloride transmembrane transport, chloride transport, cytoplasmic vesicle, early endosome, early endosome membrane, endosomal lumen acidification, endosome, external side of plasma membrane, Golgi apparatus, Golgi membrane, integral component of membrane, integral component of plasma membrane, ion channel activity, ion transport, late endosome Another extracted example is CLCN3 → anterior amygdaloid area, Brodmann area 46, cingulate gyrus, endothelial cell, Epithelium of choroid plexus, islet of Langerhans, lateral geniculate nucleus, lateral hypothalamus, lateral septal nucleus, mammillary body, mucosa of sigmoid colon, paraventricular nucleus of hypothalamus, parotid gland, postcentral gyrus, retinal pigment epithelium, right ventricle, Rostral migratory stream, subiculum, superior vestibular nucleus, ventromedial nucleus. Use these groups to spot repeated connection types before inspecting the individual relationships.

CLCN3

Top relations

Gene ontology · 44
CLCN3 → antiporter activity, ATP binding, cell surface, chloride channel activity, chloride ion binding, chloride transmembrane transport, chloride transport, cytoplasmic vesicle, early endosome, early endosome membrane, endosomal lumen acidification, endosome, external side of plasma membrane, Golgi apparatus, Golgi membrane, integral component of membrane, integral component of plasma membrane, ion channel activity, ion transport, late endosome
Bgee · 20
CLCN3 → anterior amygdaloid area, Brodmann area 46, cingulate gyrus, endothelial cell, Epithelium of choroid plexus, islet of Langerhans, lateral geniculate nucleus, lateral hypothalamus, lateral septal nucleus, mammillary body, mucosa of sigmoid colon, paraventricular nucleus of hypothalamus, parotid gland, postcentral gyrus, retinal pigment epithelium, right ventricle, Rostral migratory stream, subiculum, superior vestibular nucleus, ventromedial nucleus
RNA expression pattern · 20
CLCN3 → anterior amygdaloid area, Brodmann area 46, cingulate gyrus, endothelial cell, Epithelium of choroid plexus, islet of Langerhans, lateral geniculate nucleus, lateral hypothalamus, lateral septal nucleus, mammillary body, mucosa of sigmoid colon, paraventricular nucleus of hypothalamus, parotid gland, postcentral gyrus, retinal pigment epithelium, right ventricle, Rostral migratory stream, subiculum, superior vestibular nucleus, ventromedial nucleus
Band · 2
CLCN3 → 4q33, 8 B3.1|8 30.9 cM
Chr. · 2
CLCN3 → Chromosome 4 (human), Chromosome 8 (mouse)
End · 2
CLCN3 → 169,723,673 bp, 61,436,334 bp
related to Interactions · 2
CLCN3 → PDZK1, TMEM9
Aliases · 1
CLCN3 → CLCN3, CLC3, ClC-3, chloride voltage-gated channel 3, NEDSBA, NEDHYBA
BioGPS · 1
CLCN3 → More reference expression data
Databases · 1
CLCN3 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human bp gene chr band chromosome location protein external chloride channel mouse voltage-gated 723 673 end 169 b3 30 436

CLCN3 relationships Subject–Predicate–Object triples

TTTA extracted 106 structured relationships around CLCN3. Examples in this analysis include CLCN3 → Aliases → CLCN3, CLC3, ClC-3, chloride voltage-gated channel 3, NEDSBA, NEDHYBA and CLCN3 → Band → 4q33. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CLCN3AliasesCLCN3, CLC3, ClC-3, chloride voltage-gated channel 3, NEDSBA, NEDHYBA1.00infobox
CLCN3Band4q331.00infobox
CLCN3Band8 B3.1|8 30.9 cM1.00infobox
CLCN3Bgeemucosa of sigmoid colon1.00infobox
CLCN3Bgeeendothelial cell1.00infobox
CLCN3BgeeBrodmann area 461.00infobox
CLCN3BgeeEpithelium of choroid plexus1.00infobox
CLCN3Bgeeretinal pigment epithelium1.00infobox
CLCN3Bgeepostcentral gyrus1.00infobox
CLCN3Bgeeislet of Langerhans1.00infobox
CLCN3Bgeeparotid gland1.00infobox
CLCN3Bgeeright ventricle1.00infobox
CLCN3Bgeesuperior vestibular nucleus1.00infobox
CLCN3BgeeRostral migratory stream1.00infobox
CLCN3Bgeemammillary body1.00infobox
CLCN3Bgeelateral septal nucleus1.00infobox
CLCN3Bgeeventromedial nucleus1.00infobox
CLCN3Bgeelateral geniculate nucleus1.00infobox
CLCN3Bgeelateral hypothalamus1.00infobox
CLCN3Bgeecingulate gyrus1.00infobox
CLCN3Bgeeanterior amygdaloid area1.00infobox
CLCN3Bgeeparaventricular nucleus of hypothalamus1.00infobox
CLCN3Bgeesubiculum1.00infobox
CLCN3BioGPSMore reference expression data1.00infobox
CLCN3Chr.Chromosome 4 (human)1.00infobox
CLCN3Chr.Chromosome 8 (mouse)1.00infobox
CLCN3DatabasesNCBI: entry; OMA: entry1.00infobox
CLCN3End169,723,673 bp1.00infobox
CLCN3End61,436,334 bp1.00infobox
CLCN3EnsemblENSG000001095721.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around CLCN3 bring nearby vocabulary together. In this analysis, examples include Gene, Channel and Chloride. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • CLCN3
    • Gene
    • Channel
    • Chloride
    • Protein
    • Human
    • Location
    • External
    • Ucsc
    • Voltage-gated
    • Chromosome
    • Bp
    • Chr
  • clcn3
    • Gene
    • Channel
    • Chloride
    • Protein
    • Human
    • Location
    • External
    • Ucsc
    • Voltage-gated
    • Chromosome
    • Bp
    • Chr
  • gene
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • B3
    • End
    • External
    • Mouse
    • Ucsc
    • Voltage-gated
    • Channel
  • interactions
    • Also
    • Links
    • Reading
    • References
    • See
    • External
    • Voltage-gated
    • Channel
    • Chloride
    • Chromosome
    • Location
    • Bp
  • protein
    • Ucsc
    • Voltage-gated

Connections between topic areas Semantic bridges

For CLCN3, one of the stronger structural bridges in this analysis connects CLCN3 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CLCN3 — Interactions · splits 4 ⟂ 4
CLCN3 — Overview · splits 5 ⟂ 3

Map overview Semantic statistics

CLCN3

Nodes8
Edges7
Triples106
Avg. degree1.75
Density0.25
Components1

Source & methodology

TTTA analyzes the structure around CLCN3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CLCN3 · EN edition · Analysis: TopicsToTalkAbout

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