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Chlorpropamide

Chlorpropamide is a diabetes medication, belonging to the sulfonylurea class of organic compounds. It is used to treat diabetes mellitus type 2. It is a long-acting first-generation sulfonylurea.

Cautions and contraindications, Mechanism of action & Pharmacokinetics

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Explore the main themes, entities and connections around Chlorpropamide. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Cautions and contraindications

16 related topics

Mechanism of action

10 related topics

Pharmacokinetics

6 related topics

Chemical properties

2 related topics

Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
A10BB02 (WHO)
Bioavailability
>90%
CAS Number
94-20-2 Y
ChEBI
CHEBI:3650 Y

Topics to explore

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Overview

Mechanism of action

Pharmacokinetics

Cautions and contraindications

Chemical properties

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Map overview Semantic statistics

Chlorpropamide

Nodes43
Edges42
Triples54
Avg. degree1.95
Density0.046512
Components1

How this topic connects Entity context

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Chlorpropamide

Top relations

has effect · 7
Chlorpropamide → ADH, In, It, Johnson, Less, Stevens, The
Legal status · 4
Chlorpropamide → AU: S4 (Prescription only), CA: ℞-only, UK: POM (Prescription only), US: ℞-only
related to Cautions and contraindications · 3
Chlorpropamide → Glucophage, Metformin, Sulfonylureas
related to Mechanism of action · 3
Chlorpropamide → It, Like, The
related to Pharmacokinetics · 3
Chlorpropamide → It, Maximal, More
related to Chemical properties · 2
Chlorpropamide → It, Its
3D model (JSmol) · 1
Chlorpropamide → Interactive image
AHFS/Drugs.com · 1
Chlorpropamide → Monograph
ATC code · 1
Chlorpropamide → A10BB02 (WHO)
Bioavailability · 1
Chlorpropamide → 90%

Important terminology Word statistics

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Important terminology

plasma sulfonylureas patients used diabetes sulfonylurea renal drug side effects also 90 hours secretion hypoglycemia tolbutamide elderly hepatic binding 36

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Chlorpropamide3D model (JSmol)Interactive image1.00infobox
ChlorpropamideAHFS/Drugs.comMonograph1.00infobox
ChlorpropamideATC codeA10BB02 (WHO)1.00infobox
ChlorpropamideBioavailability>90%1.00infobox
ChlorpropamideCAS Number94-20-2 Y1.00infobox
ChlorpropamideChEBICHEBI:3650 Y1.00infobox
ChlorpropamideChEMBLChEMBL498 Y1.00infobox
ChlorpropamideChemSpider2626 Y1.00infobox
ChlorpropamideCompTox Dashboard (EPA)DTXSID90203221.00infobox
ChlorpropamideDrugBankDB00672 Y1.00infobox
ChlorpropamideECHA InfoCard100.002.1041.00infobox
ChlorpropamideElimination half-life36 hours1.00infobox
ChlorpropamideExcretionRenal (glomerular filtration → reabsorption → tubular secretion)1.00infobox
ChlorpropamideFormulaC10H13ClN2O3S1.00infobox
ChlorpropamideIUPHAR/BPS68011.00infobox
ChlorpropamideKEGGD00271 Y1.00infobox
ChlorpropamideLegal statusAU: S4 (Prescription only)1.00infobox
ChlorpropamideLegal statusCA: ℞-only1.00infobox
ChlorpropamideLegal statusUK: POM (Prescription only)1.00infobox
ChlorpropamideLegal statusUS: ℞-only1.00infobox
ChlorpropamideLicense dataUS FDA: Chlorpropamide1.00infobox
ChlorpropamideMedlinePlusa6824791.00infobox
ChlorpropamideMelting point126 to 130 °C (259 to 266 °F)1.00infobox
ChlorpropamideMetabolism<1%1.00infobox
ChlorpropamideMolar mass276.74 g·mol−11.00infobox
ChlorpropamidePregnancy categoryAU: C1.00infobox
ChlorpropamideProtein binding90%1.00infobox
ChlorpropamidePubChem CID27271.00infobox
ChlorpropamideRoutes of administrationOral1.00infobox
ChlorpropamideTrade namesDiabinese1.00infobox

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