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Cefiderocol

Cefiderocol, sold under the brand name Fetroja (by Shionogi) among others, is an antibiotic used to treat complicated urinary tract infections when no other options are available. It is indicated for the treatment of multi-drug-resistant Gram-negative bacteria including Pseudomonas aeruginosa. It is given by injection into a vein.

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
J01DI04 (WHO)
CAS Number
1225208-94-5
ChEBI
CHEBI:140376
ChEMBL
ChEMBL3989974

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Overview

Medical uses

Adverse effects

Pharmacology

In vitro activity

History

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Map overview Semantic statistics

Cefiderocol

Nodes49
Edges48
Triples85
Avg. degree1.96
Density0.040816
Components1

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Cefiderocol

Top relations

related to External links · 16
Cefiderocol → APEKS-cUTI, Archived, Clinical, ClinicalTrials, Complicated Urinary Tract Infections, Drug Information Portal, Efficacy, Intravenous Cefiderocol, Medicine, National Library, NCT02321800, November, S-649266, Safety, Study, Versus Imipenem/Cilastatin
related to history · 13
Cefiderocol → Co, Drug Administration, Europe, FDA, Food, Gram-negative, In November, Mexico, Of, Qualified Infectious Disease Product, Shionogi, The, United States
related to Pharmacology · 9
Cefiderocol → C-3, Drug Administration, FDA, Food, It, Its, Once, PBPs, This
related to Medical uses · 8
Cefiderocol → Enterobacter, Escherichia, Gram-negative, In, Klebsiella, Proteus, Pseudomonas, United States
related to In vitro activity · 6
Cefiderocol → According, Antimicrobial Susceptibility Testing, European Committee, Mueller-Hinton, To, Trojan
has effect · 4
Cefiderocol → An, Gram-negative, Hence, The
Legal status · 3
Cefiderocol → EU: Rx-only, In general: ℞ (Prescription only), US: ℞-only
KEGG · 2
Cefiderocol → D11013, D11302
License data · 2
Cefiderocol → EU EMA: by INN, US DailyMed: Cefiderocol_sulfate_tosylate
3D model (JSmol) · 1
Cefiderocol → Interactive image

Important terminology Word statistics

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Important terminology

infections treatment gram-negative drug complicated urinary tract bacteria 2020 participants including caused antibiotic options european infusion fetroja iron trial indicated

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Cefiderocol3D model (JSmol)Interactive image1.00infobox
CefiderocolAHFS/Drugs.comMonograph1.00infobox
CefiderocolATC codeJ01DI04 (WHO)1.00infobox
CefiderocolCAS Number1225208-94-51.00infobox
CefiderocolChEBICHEBI:1403761.00infobox
CefiderocolChEMBLChEMBL39899741.00infobox
CefiderocolChemSpider520849021.00infobox
CefiderocolCompTox Dashboard (EPA)DTXSID4010980521.00infobox
CefiderocolDrug classSiderophore cephalosporins1.00infobox
CefiderocolDrugBankDB148791.00infobox
CefiderocolElimination half-life2.8 hours1.00infobox
CefiderocolExcretionmainly kidney (60–70% unchanged)1.00infobox
CefiderocolFormulaC30H34ClN7O10S21.00infobox
CefiderocolKEGGD110131.00infobox
CefiderocolKEGGD113021.00infobox
CefiderocolLegal statusUS: ℞-only1.00infobox
CefiderocolLegal statusEU: Rx-only1.00infobox
CefiderocolLegal statusIn general: ℞ (Prescription only)1.00infobox
CefiderocolLicense dataEU EMA: by INN1.00infobox
CefiderocolLicense dataUS DailyMed: Cefiderocol_sulfate_tosylate1.00infobox
CefiderocolMedlinePlusa6200081.00infobox
CefiderocolMolar mass752.21 g·mol−11.00infobox
CefiderocolOther namesRSC-6492661.00infobox
CefiderocolProtein binding56–58%1.00infobox
CefiderocolPubChem CID778439661.00infobox
CefiderocolRoutes of administrationIntravenous infusion1.00infobox
CefiderocolTrade namesFetroja, Fetcroja1.00infobox
CefiderocolUNIISZ34OMG6E81.00infobox

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