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Cefepime: Applications, Medical use & Chemistry

Cefepime is a fourth-generation cephalosporin antibiotic. Cefepime has an extended spectrum of activity against Gram-positive and Gram-negative bacteria, with greater activity against both types of organism than third-generation agents. A 2007 meta-analysis suggested when data of trials were combined, mortality was increased in people treated with…

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Cefepime topic overview

The analysis highlights Applications, Medical use and Chemistry as prominent areas in the source structure around Cefepime.

Related topics
36
Source areas
3
Connected nodes
39
Extracted relationships
66
Concept neighborhoods
19
Bridge connections
39

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Medical use · 19 topics
Overview · 12 topics
Chemistry · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
J01DE01 (WHO)
Bioavailability
100% (IM)
CAS Number
88040-23-7 Y
ChEBI
CHEBI:478164 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical use

Chemistry

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Cefepime connects Entity context

The extracted context around Cefepime shows recurring relationship patterns in the source. For example, Cefepime → Axepim, Bristol-Myers Squibb, Cepimax, Cepimex, Following, Maxipime, Neomed, Neopime Another extracted example is Cefepime → Gram-negative, Pseudomonas, Staphylococcus, The, The N-methyl, These. Use these groups to spot repeated connection types before inspecting the individual relationships.

Cefepime

Top relations

related to Trade names · 8
Cefepime → Axepim, Bristol-Myers Squibb, Cepimax, Cepimex, Following, Maxipime, Neomed, Neopime
related to Chemistry · 6
Cefepime → Gram-negative, Pseudomonas, Staphylococcus, The, The N-methyl, These
related to External links · 6
Cefepime → Archived, August, Drug Information Portal, Medicine, National Library, October
related to Spectrum of bacterial susceptibility · 6
Cefepime → Escherichia, MIC, Pseudomonas, Some, Streptococcus, The
related to Medical use · 5
Cefepime → Enterobacteriaceae, Pseudomonas, Staphylococcus, Streptococcus, Whereas
Legal status · 4
Cefepime → AU: S4 (Prescription only), CA: ℞-only, UK: POM (Prescription only), US: ℞-only
related to Cefepime induced neurotoxicity · 4
Cefepime → GABA, ICU, Symptoms, Up
3D model (JSmol) · 1
Cefepime → Interactive image
AHFS/Drugs.com · 1
Cefepime → Monograph
ATC code · 1
Cefepime → J01DE01 (WHO)

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bacteria trade names pseudomonas activity drug medical meta-analysis mortality data administration aeruginosa spectrum use cephalosporin antibiotic gram-negative including streptococcus symptoms

Cefepime relationships Subject–Predicate–Object triples

TTTA extracted 66 structured relationships around Cefepime. Examples in this analysis include Cefepime → 3D model (JSmol) → Interactive image and Cefepime → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Cefepime3D model (JSmol)Interactive image1.00infobox
CefepimeAHFS/Drugs.comMonograph1.00infobox
CefepimeATC codeJ01DE01 (WHO)1.00infobox
CefepimeBioavailability100% (IM)1.00infobox
CefepimeCAS Number88040-23-7 Y1.00infobox
CefepimeChEBICHEBI:478164 Y1.00infobox
CefepimeChEMBLChEMBL186 Y1.00infobox
CefepimeChemSpider4586395 Y1.00infobox
CefepimeCompTox Dashboard (EPA)DTXSID708732081.00infobox
CefepimeDrugBankDB01413 Y1.00infobox
CefepimeECHA InfoCard100.171.0251.00infobox
CefepimeElimination half-life2 hours1.00infobox
CefepimeExcretionRenal 70–99%1.00infobox
CefepimeFormulaC19H24N6O5S21.00infobox
CefepimeKEGGD02376 Y1.00infobox
CefepimeLegal statusAU: S4 (Prescription only)1.00infobox
CefepimeLegal statusCA: ℞-only1.00infobox
CefepimeLegal statusUK: POM (Prescription only)1.00infobox
CefepimeLegal statusUS: ℞-only1.00infobox
CefepimeLicense dataUS DailyMed: Cefepime1.00infobox
CefepimeMedlinePlusa6980211.00infobox
CefepimeMelting point150 °C (302 °F) (dec.)1.00infobox
CefepimeMetabolismHepatic 15%1.00infobox
CefepimeMolar mass480.56 g·mol−11.00infobox
CefepimePregnancy categoryAU: B11.00infobox
CefepimePronunciation/ˈsɛfɪpiːm/ or /ˈkɛfɪpiːm/1.00infobox
CefepimePubChem CID54795371.00infobox
CefepimeRoutes of administrationIntravenous, intramuscular1.00infobox
CefepimeTrade namesMaxipime, Voco1.00infobox
CefepimeUNII807PW4VQE31.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Cefepime bring nearby vocabulary together. In this analysis, examples include Data, Including and Medical. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Cefepime
    • Data
    • Including
    • Medical
    • Symptoms
    • Activity
    • Aeruginosa
    • Pseudomonas
    • Antibiotic
    • Bristol-myers
    • Cephalosporin
    • Induced
    • Maxipime
  • cefepime
    • Data
    • Including
    • Medical
    • Symptoms
    • Activity
    • Aeruginosa
    • Pseudomonas
    • Antibiotic
    • Bristol-myers
    • Cephalosporin
    • Induced
    • Maxipime
  • food and drug administration
    • Status
    • Available
    • Generic
    • Induced
    • Maxipime
    • Meta-analysis
    • Mortality
    • Names
    • Neurotoxicity
    • Pneumonia
    • Renal
    • Spectrum
  • medical use
    • Medical
    • Pneumonia
    • Treat
    • Use
    • Bristol-myers
    • Induced
    • Maxipime
    • Names
    • Neurotoxicity
    • Renal
    • Spectrum
    • Squibb
  • bacteria
    • Gram-negative
    • Moiety
    • Gram-positive
    • Cephalosporin
    • Enterobacteriaceae
    • Pneumonia
    • Spectrum
    • Treat
    • Medical
    • Streptococcus
    • Cefepime
    • Pseudomonas
  • generic drug
    • Worldwide
    • Maxipime
    • Names
    • Squibb
    • Trade
    • Available
    • Generic
    • Including
    • Meta-analysis
    • Mortality
  • bristol-myers squibb
    • Squibb
    • Available
    • Generic
    • Maxipime
    • Use
    • Worldwide
    • Including
    • Medical
    • Cefepime
  • pneumonia
    • Treat
    • Cephalosporin
    • Enterobacteriaceae
    • Renal
    • Spectrum
    • Status
    • Susceptibility
    • Trade
    • Use

Connections between topic areas Semantic bridges

For Cefepime, one of the stronger structural bridges in this analysis connects Cefepime with Medical use. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Cefepime — Medical use · splits 20 ⟂ 20
Cefepime — Overview · splits 27 ⟂ 13
Cefepime — Chemistry · splits 34 ⟂ 6

Map overview Semantic statistics

Cefepime

Nodes40
Edges39
Triples66
Avg. degree1.95
Density0.05
Components1

Source & methodology

TTTA analyzes the structure around Cefepime to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Medical use & Chemistry, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Cefepime · EN edition · Analysis: TopicsToTalkAbout

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