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CDC34: Interactions & Overview

CDC34 is a gene that in humans encodes the protein Ubiquitin-conjugating enzyme E2 R1. This protein is a member of the ubiquitin-conjugating enzyme family, which catalyzes the covalent attachment of ubiquitin to other proteins.

Language: English [EN]
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CDC34 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around CDC34.

Related topics
16
Source areas
2
Connected nodes
18
Extracted relationships
96
Concept neighborhoods
13
Bridge connections
18

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 12 topics
Interactions · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.3.2.23
2.3.2.24
Aliases
CDC34, E2-UBC3, UBCH3, UBE2R1, cell division cycle 34, cell division cycle 34, ubiqiutin conjugating enzyme
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2OB4, 3RZ3, 4MDK
Band
19p13.3 · 10 C1|10 39.72 cM
Bgee
left testis · right testis · apex of heart · ventricular zone · right hemisphere of cerebellum

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CDC34 connects Entity context

The extracted context around CDC34 shows recurring relationship patterns in the source. For example, CDC34 → ATP binding, cell cycle, cellular response to interferon-beta, cytoplasm, cytosol, DNA replication initiation, G1/S transition of mitotic cell cycle, negative regulation of cAMP-mediated signaling, nuclear speck, nucleoplasm, nucleotide binding, nucleus, positive regulation of inclusion body assembly, positive regulation of neuron apoptotic process, proteasome-mediated ubiquitin-dependent protein catabolic process, protein binding, protein K48-linked ubiquitination, protein polyubiquitination, protein ubiquitination, response to growth factor Another extracted example is CDC34 → apex of heart, epiblast, ganglionic eminence, gastrocnemius muscle, left testis, lip, muscle layer of sigmoid colon, muscle of thigh, muscle tissue, placenta, quadriceps femoris muscle, right hemisphere of cerebellum, right lobe of liver, right testis, skeletal muscle tissue, testicle, ventricular zone, white adipose tissue, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

CDC34

Top relations

Gene ontology · 26
CDC34 → ATP binding, cell cycle, cellular response to interferon-beta, cytoplasm, cytosol, DNA replication initiation, G1/S transition of mitotic cell cycle, negative regulation of cAMP-mediated signaling, nuclear speck, nucleoplasm, nucleotide binding, nucleus, positive regulation of inclusion body assembly, positive regulation of neuron apoptotic process, proteasome-mediated ubiquitin-dependent protein catabolic process, protein binding, protein K48-linked ubiquitination, protein polyubiquitination, protein ubiquitination, response to growth factor
Bgee · 19
CDC34 → apex of heart, epiblast, ganglionic eminence, gastrocnemius muscle, left testis, lip, muscle layer of sigmoid colon, muscle of thigh, muscle tissue, placenta, quadriceps femoris muscle, right hemisphere of cerebellum, right lobe of liver, right testis, skeletal muscle tissue, testicle, ventricular zone, white adipose tissue, yolk sac
RNA expression pattern · 19
CDC34 → apex of heart, epiblast, ganglionic eminence, gastrocnemius muscle, left testis, lip, muscle layer of sigmoid colon, muscle of thigh, muscle tissue, placenta, quadriceps femoris muscle, right hemisphere of cerebellum, right lobe of liver, right testis, skeletal muscle tissue, testicle, ventricular zone, white adipose tissue, yolk sac
related to Interactions · 3
CDC34 → BTRC, CDK9, CSNK2B
Band · 2
CDC34 → 10 C1|10 39.72 cM, 19p13.3
Chr. · 2
CDC34 → Chromosome 10 (mouse), Chromosome 19 (human)
End · 2
CDC34 → 542,092 bp, 79,524,232 bp
related to External links · 2
CDC34 → Human CDC34, UCSC Genome Browser
2.3.2.23 · 1
CDC34 → ↗
2.3.2.24 · 1
CDC34 → ↗

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp protein human chr band enzyme cell cycle chromosome 19 location ubiquitin-conjugating yeast ubiquitin-mediated degradation ubiquitin g1 mouse initiation

CDC34 relationships Subject–Predicate–Object triples

TTTA extracted 96 structured relationships around CDC34. Examples in this analysis include CDC34 → 2.3.2.23 → ↗ and CDC34 → Aliases → CDC34, E2-UBC3, UBCH3, UBE2R1, cell division cycle 34, cell division cycle 34, ubiqiutin conjugating enzyme. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CDC342.3.2.231.00infobox
CDC342.3.2.241.00infobox
CDC34AliasesCDC34, E2-UBC3, UBCH3, UBE2R1, cell division cycle 34, cell division cycle 34, ubiqiutin conjugating enzyme1.00infobox
CDC34Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2OB4, 3RZ3, 4MDK1.00infobox
CDC34Band19p13.31.00infobox
CDC34Band10 C1|10 39.72 cM1.00infobox
CDC34Bgeeleft testis1.00infobox
CDC34Bgeeright testis1.00infobox
CDC34Bgeeapex of heart1.00infobox
CDC34Bgeeventricular zone1.00infobox
CDC34Bgeeright hemisphere of cerebellum1.00infobox
CDC34Bgeemuscle layer of sigmoid colon1.00infobox
CDC34Bgeemuscle of thigh1.00infobox
CDC34Bgeeganglionic eminence1.00infobox
CDC34Bgeeright lobe of liver1.00infobox
CDC34Bgeegastrocnemius muscle1.00infobox
CDC34Bgeequadriceps femoris muscle1.00infobox
CDC34Bgeemuscle tissue1.00infobox
CDC34Bgeeskeletal muscle tissue1.00infobox
CDC34Bgeeepiblast1.00infobox
CDC34Bgeetesticle1.00infobox
CDC34Bgeeplacenta1.00infobox
CDC34Bgeelip1.00infobox
CDC34Bgeewhite adipose tissue1.00infobox
CDC34Bgeeyolk sac1.00infobox
CDC34BioGPSMore reference expression data1.00infobox
CDC34Chr.Chromosome 19 (human)1.00infobox
CDC34Chr.Chromosome 10 (mouse)1.00infobox
CDC34DatabasesNCBI: entry; OMA: entry1.00infobox
CDC34End542,092 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around CDC34 bring nearby vocabulary together. In this analysis, examples include Gene, Cell and Cycle. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • CDC34
    • Gene
    • Cell
    • Cycle
    • Enzyme
    • Location
    • Protein
    • Human
    • Activity
    • Conjugating
    • Degradation
    • Dna
    • G1
  • cdc34
    • Gene
    • Cell
    • Cycle
    • Enzyme
    • Location
    • Protein
    • Human
    • Activity
    • Conjugating
    • Degradation
    • Dna
    • G1
  • gene
    • Location
    • Human
    • Cell
    • Chromosome
    • Cycle
    • Enzyme
    • Bp
    • Chr
    • Activity
    • C1
    • Conjugating
    • End
  • protein
    • Ubiquitin
    • Ubiquitin-conjugating
    • Covalent
    • Sic1
    • Activity
    • C1
    • Conjugating
    • Degradation
    • Dna
    • End
    • G1
    • Initiation
  • ubiquitin-conjugating enzyme
    • Protein
    • Activity
    • Conjugating
    • Covalent
    • Encodes
    • Enzyme
    • Humans
    • Search
    • Ubiquitin
    • Ubiquitin-conjugating
    • Gene
    • Cell
  • cell cycle
    • Cycle
    • Activity
    • Conjugating
    • Dna
    • G1
    • Initiation
    • Replication
    • Search
    • Gene
    • Chromosome
    • Enzyme
    • Location
  • protein degradation
    • Ubiquitin-mediated
    • Sic1
    • Ubiquitin
    • Ubiquitin-conjugating
    • Dna
    • G1
    • Initiation
    • Replication
    • Yeast
    • Covalent
    • Activity
    • C1
  • dna replication
    • G1
    • Initiation
    • Replication
    • Activity
    • C1
    • Conjugating
    • End
    • Mouse
    • Search
    • Ubiquitin
    • Ubiquitin-mediated
    • Ucsc

Connections between topic areas Semantic bridges

For CDC34, one of the stronger structural bridges in this analysis connects CDC34 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CDC34Overview · splits 6 ⟂ 13
CDC34Interactions · splits 14 ⟂ 5

Map overview Semantic statistics

CDC34

Nodes19
Edges18
Triples96
Avg. degree1.89
Density0.105263
Components1

Source & methodology

TTTA analyzes the structure around CDC34 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CDC34 · EN edition · Analysis: TopicsToTalkAbout

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