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Caveolin 3: Interactions, Cardiac physiology & Function

Caveolin-3 is a protein that in humans is encoded by the CAV3 gene. Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

Language: English [EN]
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Caveolin 3 topic overview

The analysis highlights Interactions, Cardiac physiology and Function as prominent areas in the source structure around Caveolin 3.

Related topics
22
Source areas
6
Connected nodes
28
Extracted relationships
157
Concept neighborhoods
13
Bridge connections
28

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 6 topics
Cardiac physiology · 5 topics
Interactions · 5 topics
Clinical significance · 2 topics
Function · 2 topics
Structure · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CAV3, LGMD1C, LQT9, VIP-21, VIP21, caveolin 3, MPDT, RMD2
Band
3p25.3 · 6 E3|6 52.26 cM
Bgee
muscle of thigh · vastus lateralis muscle · triceps brachii muscle · Skeletal muscle tissue of rectus abdominis · biceps brachii
BioGPS
More reference expression data
Chr.
Chromosome 3 (human) · Chromosome 6 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Interactions

Structure

Cardiac physiology

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Caveolin 3 connects Entity context

The extracted context around Caveolin 3 shows recurring relationship patterns in the source. For example, Caveolin 3 → actin filament organization, alpha-tubulin binding, calcium channel regulator activity, cardiac muscle cell development, caveola, caveola assembly, cell differentiation, cell surface, cellular response to organonitrogen compound, cholesterol homeostasis, connexin binding, cytoplasm, cytoplasmic microtubule organization, detection of muscle stretch, dystrophin-associated glycoprotein complex, endocytosis, endoplasmic reticulum, enzyme binding, focal adhesion, glucose homeostasis Another extracted example is Caveolin 3 → biceps brachii, cardiac muscle tissue of left ventricle, deltoid muscle, extensor digitorum longus muscle, extraocular muscle, gastrocnemius muscle, interventricular septum, masseter muscle, muscle of thigh, plantaris muscle, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, temporal muscle, thoracic diaphragm, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle. Use these groups to spot repeated connection types before inspecting the individual relationships.

Caveolin 3

Top relations

Gene ontology · 97
Caveolin 3 → actin filament organization, alpha-tubulin binding, calcium channel regulator activity, cardiac muscle cell development, caveola, caveola assembly, cell differentiation, cell surface, cellular response to organonitrogen compound, cholesterol homeostasis, connexin binding, cytoplasm, cytoplasmic microtubule organization, detection of muscle stretch, dystrophin-associated glycoprotein complex, endocytosis, endoplasmic reticulum, enzyme binding, focal adhesion, glucose homeostasis
Bgee · 18
Caveolin 3 → biceps brachii, cardiac muscle tissue of left ventricle, deltoid muscle, extensor digitorum longus muscle, extraocular muscle, gastrocnemius muscle, interventricular septum, masseter muscle, muscle of thigh, plantaris muscle, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, temporal muscle, thoracic diaphragm, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle
RNA expression pattern · 18
Caveolin 3 → biceps brachii, cardiac muscle tissue of left ventricle, deltoid muscle, extensor digitorum longus muscle, extraocular muscle, gastrocnemius muscle, interventricular septum, masseter muscle, muscle of thigh, plantaris muscle, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, temporal muscle, thoracic diaphragm, tibialis anterior muscle, triceps brachii muscle, vastus lateralis muscle
related to Interactions · 4
Caveolin 3 → Caveolin, DAG1, DYSF, EGFR
Band · 2
Caveolin 3 → 3p25.3, 6 E3|6 52.26 cM
Chr. · 2
Caveolin 3 → Chromosome 3 (human), Chromosome 6 (mouse)
End · 2
Caveolin 3 → 112,449,833 bp, 8,841,808 bp
Aliases · 1
Caveolin 3 → CAV3, LGMD1C, LQT9, VIP-21, VIP21, caveolin 3, MPDT, RMD2
BioGPS · 1
Caveolin 3 → More reference expression data
Databases · 1
Caveolin 3 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

caveolin-3 cardiac gene caveolin bp caveolae expression chr human band cav3 myocytes chromosome protein channels cellular proteins mutations location function

Caveolin 3 relationships Subject–Predicate–Object triples

TTTA extracted 157 structured relationships around Caveolin 3. Examples in this analysis include Caveolin 3 → Aliases → CAV3, LGMD1C, LQT9, VIP-21, VIP21, caveolin 3, MPDT, RMD2 and Caveolin 3 → Band → 3p25.3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Caveolin 3AliasesCAV3, LGMD1C, LQT9, VIP-21, VIP21, caveolin 3, MPDT, RMD21.00infobox
Caveolin 3Band3p25.31.00infobox
Caveolin 3Band6 E3|6 52.26 cM1.00infobox
Caveolin 3Bgeemuscle of thigh1.00infobox
Caveolin 3Bgeevastus lateralis muscle1.00infobox
Caveolin 3Bgeetriceps brachii muscle1.00infobox
Caveolin 3BgeeSkeletal muscle tissue of rectus abdominis1.00infobox
Caveolin 3Bgeebiceps brachii1.00infobox
Caveolin 3BgeeSkeletal muscle tissue of biceps brachii1.00infobox
Caveolin 3Bgeethoracic diaphragm1.00infobox
Caveolin 3Bgeegastrocnemius muscle1.00infobox
Caveolin 3Bgeedeltoid muscle1.00infobox
Caveolin 3Bgeetibialis anterior muscle1.00infobox
Caveolin 3Bgeecardiac muscle tissue of left ventricle1.00infobox
Caveolin 3Bgeeinterventricular septum1.00infobox
Caveolin 3Bgeeplantaris muscle1.00infobox
Caveolin 3Bgeesoleus muscle1.00infobox
Caveolin 3Bgeeextensor digitorum longus muscle1.00infobox
Caveolin 3Bgeetemporal muscle1.00infobox
Caveolin 3Bgeemasseter muscle1.00infobox
Caveolin 3Bgeeextraocular muscle1.00infobox
Caveolin 3BioGPSMore reference expression data1.00infobox
Caveolin 3Chr.Chromosome 3 (human)1.00infobox
Caveolin 3Chr.Chromosome 6 (mouse)1.00infobox
Caveolin 3DatabasesNCBI: entry; OMA: entry1.00infobox
Caveolin 3End8,841,808 bp1.00infobox
Caveolin 3End112,449,833 bp1.00infobox
Caveolin 3EnsemblENSG000001825331.00infobox
Caveolin 3Entrez8591.00infobox
Caveolin 3External IDsOMIM: 601253; MGI: 107570; GeneCards: CAV31.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Caveolin 3 bring nearby vocabulary together. In this analysis, examples include Channel, Function and Ion. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Caveolin 3
    • Channel
    • Function
    • Ion
    • Location
    • Potassium
    • Chromosome
    • Human
    • Protein
    • Bp
    • Channels
    • Chr
    • Proteins
  • caveolin 3
    • Channel
    • Function
    • Ion
    • Location
    • Potassium
    • Chromosome
    • Human
    • Protein
    • Bp
    • Channels
    • Chr
    • Proteins
  • gene
    • Location
    • Chromosome
    • Human
    • Protein
    • Bp
    • Chr
    • Mouse
    • Calcium
    • Channel
    • Function
    • Identified
    • Ion
  • atp-dependent potassium channels
    • Calcium
    • Channel
    • Ion
    • Potassium
    • Potential
    • Caveolin
    • Negative
    • Regulation
    • Signaling
    • Protein
    • Contraction
    • Function
  • l-type calcium channels
    • Channel
    • Contraction
    • Function
    • Ion
    • Location
    • Potassium
    • Cav3
    • Chromosome
    • Human
    • Bp
    • Calcium
    • Channels
  • caveolin
    • Channel
    • Function
    • Ion
    • Location
    • Potassium
    • Chromosome
    • Human
    • Protein
    • Bp
    • Channels
    • Chr
    • Proteins
  • caveolae
    • Myocytes
    • Contraction
    • Homeostasis
    • Involved
    • Potassium
    • Including
    • Protein
    • Cellular
    • Gene
    • Expression
    • Caveolin-3
    • Mouse
  • function
    • Calcium
    • Channel
    • Ion
    • Location
    • Potassium
    • Chromosome
    • Human
    • Bp
    • Chr
    • Gene
    • Caveolin
    • Expression

Connections between topic areas Semantic bridges

For Caveolin 3, one of the stronger structural bridges in this analysis connects Caveolin 3 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Caveolin 3Overview · splits 22 ⟂ 7
Caveolin 3Interactions · splits 23 ⟂ 6
Caveolin 3Cardiac physiology · splits 23 ⟂ 6
Caveolin 3Function · splits 26 ⟂ 3
Caveolin 3Clinical significance · splits 26 ⟂ 3
Caveolin 3Structure · splits 26 ⟂ 3

Map overview Semantic statistics

Caveolin 3

Nodes29
Edges28
Triples157
Avg. degree1.93
Density0.068966
Components1

Source & methodology

TTTA analyzes the structure around Caveolin 3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Cardiac physiology & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Caveolin 3 · EN edition · Analysis: TopicsToTalkAbout

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