Cav2.1

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Explore the main themes, entities and connections around Cav2.1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Clinical significance

Epilepsy Polyglutamine tract

2 related topics

Interactions

Interact CACNB4

2 related topics

Overview

Voltage-dependent calcium channel Brain Neurons Cerebellum Neurotransmitters

9 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: CACNA1A, APCA, BI, CACNL1A4, CAV2.1, EA2, FHM, HPCA, MHP, MHP1, SCA6, Cav2.1, calcium voltage-gated channel subunit alpha1 A, EIEE42, DEE42
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3BXK
Band: 19p13.13 · 8 C2- C3|8 40.95 cM
Bgee: cerebellar hemisphere · right hemisphere of cerebellum · Brodmann area 23 · postcentral gyrus · pons
BioGPS: More reference expression data
Chr.: Chromosome 19 (human) · Chromosome 8 (mouse)

Topics to explore

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Overview

Clinical significance

Interactions

Interact Protein-protein interaction
CACNB4

Advanced semantic analysis

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Map overview Semantic statistics

Nodes17

Edges16

Triples96

Avg. degree1.88

Density0.117647

Components1

How this topic connects Entity context

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Cav2.1

Top relations

Gene ontology · 33

Cav2.1 → amyloid-beta binding, calcium channel activity, calcium ion import, calcium ion transmembrane transport, calcium ion transport, cell death, cell projection, cellular response to amyloid-beta, chemical synaptic transmission, cytoplasm, high voltage-gated calcium channel activity, integral component of membrane, ion channel activity, ion transport, membrane, membrane depolarization, membrane depolarization during action potential, metal ion binding, modulation of chemical synaptic transmission, nucleus

Bgee · 18

Cav2.1 → Brodmann area 23, buccal mucosa cell, cerebellar cortex, cerebellar hemisphere, cerebellar vermis, dentate gyrus of hippocampal formation granule cell, endothelial cell, inferior colliculi, lobe of cerebellum, middle temporal gyrus, neural layer of retina, pons, postcentral gyrus, primary motor cortex, primary visual cortex, right hemisphere of cerebellum, Rostral migratory stream, superior frontal gyrus

RNA expression pattern · 18

Band · 2

Cav2.1 → 19p13.13, 8 C2- C3|8 40.95 cM

Chr. · 2

Cav2.1 → Chromosome 19 (human), Chromosome 8 (mouse)

End · 2

Cav2.1 → 13,633,025 bp, 85,366,875 bp

related to Interactions · 2

Cav2.1 → CACNB4, Cav2

Aliases · 1

Cav2.1 → CACNA1A, APCA, BI, CACNL1A4, CAV2.1, EA2, FHM, HPCA, MHP, MHP1, SCA6, Cav2.1, calcium voltage-gated channel subunit alpha1 A, EIEE42, DEE42

Available structures · 1

Cav2.1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3BXK

BioGPS · 1

Cav2.1 → More reference expression data

Important terminology Word statistics

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Important terminology

calcium cacna1a gene subunit alpha-1 bp cav2 human chr band channel chromosome 19 associated disorders ataxia found including brain neurons

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Cav2.1	Aliases	CACNA1A, APCA, BI, CACNL1A4, CAV2.1, EA2, FHM, HPCA, MHP, MHP1, SCA6, Cav2.1, calcium voltage-gated channel subunit alpha1 A, EIEE42, DEE42	1.00	infobox
Cav2.1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3BXK	1.00	infobox
Cav2.1	Band	19p13.13	1.00	infobox
Cav2.1	Band	8 C2- C3\|8 40.95 cM	1.00	infobox
Cav2.1	Bgee	cerebellar hemisphere	1.00	infobox
Cav2.1	Bgee	right hemisphere of cerebellum	1.00	infobox
Cav2.1	Bgee	Brodmann area 23	1.00	infobox
Cav2.1	Bgee	postcentral gyrus	1.00	infobox
Cav2.1	Bgee	pons	1.00	infobox
Cav2.1	Bgee	primary visual cortex	1.00	infobox
Cav2.1	Bgee	superior frontal gyrus	1.00	infobox
Cav2.1	Bgee	endothelial cell	1.00	infobox
Cav2.1	Bgee	middle temporal gyrus	1.00	infobox
Cav2.1	Bgee	buccal mucosa cell	1.00	infobox
Cav2.1	Bgee	cerebellar cortex	1.00	infobox
Cav2.1	Bgee	lobe of cerebellum	1.00	infobox
Cav2.1	Bgee	cerebellar vermis	1.00	infobox
Cav2.1	Bgee	dentate gyrus of hippocampal formation granule cell	1.00	infobox
Cav2.1	Bgee	Rostral migratory stream	1.00	infobox
Cav2.1	Bgee	inferior colliculi	1.00	infobox
Cav2.1	Bgee	primary motor cortex	1.00	infobox
Cav2.1	Bgee	neural layer of retina	1.00	infobox
Cav2.1	BioGPS	More reference expression data	1.00	infobox
Cav2.1	Chr.	Chromosome 19 (human)	1.00	infobox
Cav2.1	Chr.	Chromosome 8 (mouse)	1.00	infobox
Cav2.1	Databases	NCBI: entry; OMA: entry	1.00	infobox
Cav2.1	End	13,633,025 bp	1.00	infobox
Cav2.1	End	85,366,875 bp	1.00	infobox
Cav2.1	Ensembl	ENSG00000141837	1.00	infobox
Cav2.1	Entrez	773	1.00	infobox

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