Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

GDF5

Growth/differentiation factor 5 is a protein that in humans is encoded by the GDF5 gene.

Overview, Related Topics & Entities

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around GDF5. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
GDF5, BDA1C, BMP-14, BMP14, CDMP1, LAP-4, LAP4, OS5, SYM1B, SYNS2, growth differentiation factor 5, DUPANS
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WAQ, 2BHK, 3EVS, 3QB4
Band
20q11.22 · 2 H1|2 77.26 cM
Bgee
parotid gland · pericardium · cartilage tissue · synovial joint · synovial membrane
BioGPS
More reference expression data
Chr.
Chromosome 20 (human) · Chromosome 2 (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

GDF5

Nodes11
Edges10
Triples99
Avg. degree1.82
Density0.181818
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

GDF5

Top relations

Gene ontology · 38
GDF5 → BMP binding, BMP signaling pathway, cartilage development, cell development, cell-cell signaling, chondroblast differentiation, chondrocyte differentiation, cytokine activity, embryonic limb morphogenesis, extracellular region, extracellular space, forelimb morphogenesis, growth factor activity, hindlimb morphogenesis, identical protein binding, membrane, negative regulation of chondrocyte differentiation, negative regulation of epithelial cell proliferation, negative regulation of mesenchymal cell apoptotic process, negative regulation of neuron apoptotic process
Bgee · 19
GDF5 → annulus fibrosus disci intervertebralis, cartilage tissue, cuneiform bones, elbow, finger, hand joint, interphalangeal joint of hand, joints of the foot, lacrimal gland, minor salivary glands, molar, oral mucosa, parotid gland, pericardium, pharynx, sensory nervous system, synovial joint, synovial membrane, upper respiratory tract
RNA expression pattern · 19
GDF5 → annulus fibrosus disci intervertebralis, cartilage tissue, cuneiform bones, elbow, finger, hand joint, interphalangeal joint of hand, joints of the foot, lacrimal gland, minor salivary glands, molar, oral mucosa, parotid gland, pericardium, pharynx, sensory nervous system, synovial joint, synovial membrane, upper respiratory tract
Band · 2
GDF5 → 2 H1|2 77.26 cM, 20q11.22
Chr. · 2
GDF5 → Chromosome 2 (mouse), Chromosome 20 (human)
End · 2
GDF5 → 155,787,287 bp, 35,454,746 bp
Aliases · 1
GDF5 → GDF5, BDA1C, BMP-14, BMP14, CDMP1, LAP-4, LAP4, OS5, SYM1B, SYNS2, growth differentiation factor 5, DUPANS
Available structures · 1
GDF5 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WAQ, 2BHK, 3EVS, 3QB4
BioGPS · 1
GDF5 → More reference expression data
Databases · 1
GDF5 → NCBI: entry; OMA: entry

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp protein chr human band growth differentiation chromosome 20 development factor location encoded family associated role skeletal also mouse

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
GDF5AliasesGDF5, BDA1C, BMP-14, BMP14, CDMP1, LAP-4, LAP4, OS5, SYM1B, SYNS2, growth differentiation factor 5, DUPANS1.00infobox
GDF5Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1WAQ, 2BHK, 3EVS, 3QB41.00infobox
GDF5Band20q11.221.00infobox
GDF5Band2 H1|2 77.26 cM1.00infobox
GDF5Bgeeparotid gland1.00infobox
GDF5Bgeepericardium1.00infobox
GDF5Bgeecartilage tissue1.00infobox
GDF5Bgeesynovial joint1.00infobox
GDF5Bgeesynovial membrane1.00infobox
GDF5Bgeeoral mucosa1.00infobox
GDF5Bgeeminor salivary glands1.00infobox
GDF5Bgeesensory nervous system1.00infobox
GDF5Bgeepharynx1.00infobox
GDF5Bgeeupper respiratory tract1.00infobox
GDF5Bgeefinger1.00infobox
GDF5Bgeeelbow1.00infobox
GDF5Bgeehand joint1.00infobox
GDF5Bgeejoints of the foot1.00infobox
GDF5Bgeelacrimal gland1.00infobox
GDF5Bgeeinterphalangeal joint of hand1.00infobox
GDF5Bgeeannulus fibrosus disci intervertebralis1.00infobox
GDF5Bgeemolar1.00infobox
GDF5Bgeecuneiform bones1.00infobox
GDF5BioGPSMore reference expression data1.00infobox
GDF5Chr.Chromosome 20 (human)1.00infobox
GDF5Chr.Chromosome 2 (mouse)1.00infobox
GDF5DatabasesNCBI: entry; OMA: entry1.00infobox
GDF5End35,454,746 bp1.00infobox
GDF5End155,787,287 bp1.00infobox
GDF5EnsemblENSG000001259651.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.