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Anti-CD22 immunotoxin

An anti-CD22 immunotoxin is a monoclonal antibody targeting CD22 linked to a cytotoxic agent. As of August 2009, it was studied in the treatment of some types of B-cell cancer. It binds to CD22, a receptor protein on the surface of normal B cells and B-cell tumors, and, upon internalization, kills the cells, acting as immunotoxin.

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Therapeutic immunotoxins that use Pseudomonas exotoxin

Phase IHairy cell leukemiaNIHAntibody fragmentPH
22 related topics

Overview

Monoclonal antibodyCD22Cytotoxic agentB-cellProtein
7 related topics

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Therapeutic immunotoxins that use Pseudomonas exotoxin

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Anti-CD22 immunotoxin

Nodes32
Edges31
Triples20
Avg. degree1.94
Density0.0625
Components1

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Anti-CD22 immunotoxin

Top relations

related to CAT-3888 and CAT-8015 · 10
Anti-CD22 immunotoxin → BL22, CAT-3888, CD22, Fv, NIH, PE38, Phase, Pseudomonas, Technically, The
related to External links · 6
Anti-CD22 immunotoxin → Anti-CD22, Cancer Terms, Cancer Terms This, Dictionary, National Cancer Institute, NCI Dictionary
related to Therapeutic immunotoxins that use Pseudomonas exotoxin · 3
Anti-CD22 immunotoxin → As, August, CD22
is a · 1
Anti-CD22 immunotoxin → monoclonal antibody targeting CD22 linked to a cytotoxic agent

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Important terminology

immunotoxin cat-3888 cd22 antibody anti-cd22 cancer cat-8015 pseudomonas exotoxin b-cell protein phase cell receptor surface cells leukemia nih astrazeneca cat-5001

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Anti-CD22 immunotoxinis amonoclonal antibody targeting CD22 linked to a cytotoxic agent0.90text
Anti-CD22 immunotoxinrelated to CAT-3888 and CAT-8015CAT-38880.60section
Anti-CD22 immunotoxinrelated to CAT-3888 and CAT-8015BL220.60section
Anti-CD22 immunotoxinrelated to CAT-3888 and CAT-8015CD220.60section
Anti-CD22 immunotoxinrelated to CAT-3888 and CAT-8015Phase0.60section
Anti-CD22 immunotoxinrelated to CAT-3888 and CAT-8015NIH0.60section
Anti-CD22 immunotoxinrelated to CAT-3888 and CAT-8015Technically0.60section
Anti-CD22 immunotoxinrelated to CAT-3888 and CAT-8015Fv0.60section
Anti-CD22 immunotoxinrelated to CAT-3888 and CAT-8015Pseudomonas0.60section
Anti-CD22 immunotoxinrelated to CAT-3888 and CAT-8015PE380.60section
Anti-CD22 immunotoxinrelated to CAT-3888 and CAT-8015The0.60section
Anti-CD22 immunotoxinrelated to External linksAnti-CD220.60section

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