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A single-pass membrane protein also known as single-spanning protein or bitopic protein is a transmembrane protein that spans the lipid bilayer only once. These proteins may constitute up to 50% of all transmembrane proteins, depending on the organism, and contribute significantly to the network of interactions between different proteins in cells…
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transmembrane proteins single-pass membrane protein bitopic domains different genome helix sequence domain organisms lipid bilayer depending significantly alpha several targeted
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