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Azoles are a class of five-membered heterocyclic compounds containing a nitrogen atom and at least one other non-carbon atom (i.e. nitrogen, sulfur, or oxygen) as part of the ring. Their names originate from the Hantzsch–Widman nomenclature. The parent compounds are aromatic and have two double bonds; there are successively reduced analogs (azolines and…
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azoles aromatic part ring antifungal compounds nitrogen heteroatom five-membered heterocyclic one names two double agents imidazole activity nomenclature triazoles sulfur
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| sub-optimal spectra of activity | instance of | In order to overcome limitations | 0.80 | text |
| drug-drug interactions | instance of | In order to overcome limitations | 0.80 | text |
| toxicity | instance of | In order to overcome limitations | 0.80 | text |
| development of resistance | instance of | In order to overcome limitations | 0.80 | text |
| unfavorable pharmacokinetics | instance of | In order to overcome limitations | 0.80 | text |
| analogues were developed | instance of | In order to overcome limitations | 0.80 | text |
| propiconazole | instance of | other azoles | 0.80 | text |
| tebuconazole | instance of | other azoles | 0.80 | text |
| cyproconazole | instance of | other azoles | 0.80 | text |
| are used as antifungal agents in several wood products or structures | instance of | other azoles | 0.80 | text |
| with or without the addition of copper-containing compounds | instance of | other azoles | 0.80 | text |
| Azole | related to Compound classes | ImidazolePyrazole1 | 0.60 | section |
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