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Axin-2, also known as axin-like protein (Axil), axis inhibition protein 2 (AXIN2), or conductin, is a protein that in humans is encoded by the AXIN2 gene.
The analysis highlights Function, Clinical significance and Interactions as prominent areas in the source structure around AXIN2.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around AXIN2 shows recurring relationship patterns in the source. For example, AXIN2 → beta-catenin binding, beta-catenin destruction complex, beta-catenin-TCF complex assembly, bone mineralization, cell population proliferation, centrosome, chondrocyte differentiation involved in endochondral bone morphogenesis, cytoplasm, cytosol, enzyme binding, GTPase activator activity, I-SMAD binding, intramembranous ossification, maintenance of DNA repeat elements, mRNA stabilization, multicellular organism development, negative regulation of canonical Wnt signaling pathway, negative regulation of cell population proliferation, negative regulation of osteoblast differentiation, nucleus Another extracted example is AXIN2 → anterior lobe of prostate, body of uterus, cartilage tissue, germinal epithelium, gonad, hair follicle, iris, lamina propria of urinary bladder, mucosa of ileum, Paneth cell, pelvic part of vagina, primary oocyte, primitive streak, prostatic epithelium, right lung, right uterine tube, skin of arm, tail of embryo, thymus, tibialis anterior muscle. Use these groups to spot repeated connection types before inspecting the individual relationships.
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gene human bp chr band chromosome 17 protein mouse location beta-catenin axil cancer teeth conductin complex signaling ucsc function external
TTTA extracted 107 structured relationships around AXIN2. Examples in this analysis include AXIN2 → Aliases → AXIN2, AXIL, ODCRCS, axin 2 and AXIN2 → Band → 17q24.1. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| AXIN2 | Aliases | AXIN2, AXIL, ODCRCS, axin 2 | 1.00 | infobox |
| AXIN2 | Band | 17q24.1 | 1.00 | infobox |
| AXIN2 | Band | 11 E1|11 71.83 cM | 1.00 | infobox |
| AXIN2 | Bgee | skin of arm | 1.00 | infobox |
| AXIN2 | Bgee | body of uterus | 1.00 | infobox |
| AXIN2 | Bgee | tibialis anterior muscle | 1.00 | infobox |
| AXIN2 | Bgee | thymus | 1.00 | infobox |
| AXIN2 | Bgee | germinal epithelium | 1.00 | infobox |
| AXIN2 | Bgee | right lung | 1.00 | infobox |
| AXIN2 | Bgee | mucosa of ileum | 1.00 | infobox |
| AXIN2 | Bgee | right uterine tube | 1.00 | infobox |
| AXIN2 | Bgee | cartilage tissue | 1.00 | infobox |
| AXIN2 | Bgee | gonad | 1.00 | infobox |
| AXIN2 | Bgee | primitive streak | 1.00 | infobox |
| AXIN2 | Bgee | primary oocyte | 1.00 | infobox |
| AXIN2 | Bgee | pelvic part of vagina | 1.00 | infobox |
| AXIN2 | Bgee | prostatic epithelium | 1.00 | infobox |
| AXIN2 | Bgee | hair follicle | 1.00 | infobox |
| AXIN2 | Bgee | iris | 1.00 | infobox |
| AXIN2 | Bgee | Paneth cell | 1.00 | infobox |
| AXIN2 | Bgee | anterior lobe of prostate | 1.00 | infobox |
| AXIN2 | Bgee | lamina propria of urinary bladder | 1.00 | infobox |
| AXIN2 | Bgee | tail of embryo | 1.00 | infobox |
| AXIN2 | BioGPS | More reference expression data | 1.00 | infobox |
| AXIN2 | Chr. | Chromosome 17 (human) | 1.00 | infobox |
| AXIN2 | Chr. | Chromosome 11 (mouse) | 1.00 | infobox |
| AXIN2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| AXIN2 | End | 65,561,648 bp | 1.00 | infobox |
| AXIN2 | End | 108,841,609 bp | 1.00 | infobox |
| AXIN2 | Ensembl | ENSG00000168646 | 1.00 | infobox |
The concept neighborhoods around AXIN2 bring nearby vocabulary together. In this analysis, examples include Gene, Human and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For AXIN2, one of the stronger structural bridges in this analysis connects AXIN2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around AXIN2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Clinical significance & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — AXIN2 · EN edition · Analysis: TopicsToTalkAbout
