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AXIN2

Axin-2, also known as axin-like protein (Axil), axis inhibition protein 2 (AXIN2), or conductin, is a protein that in humans is encoded by the AXIN2 gene.

Function, Clinical significance & Interactions

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Function

5 related topics

Clinical significance

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Interactions

1 related topics

Overview

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Aliases
AXIN2, AXIL, ODCRCS, axin 2
Band
17q24.1 · 11 E1|11 71.83 cM
Bgee
skin of arm · body of uterus · tibialis anterior muscle · thymus · germinal epithelium
BioGPS
More reference expression data
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Function

Clinical significance

Interactions

Advanced semantic analysis

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Map overview Semantic statistics

AXIN2

Nodes17
Edges16
Triples110
Avg. degree1.88
Density0.117647
Components1

How this topic connects Entity context

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AXIN2

Top relations

Gene ontology · 36
AXIN2 → beta-catenin binding, beta-catenin destruction complex, beta-catenin-TCF complex assembly, bone mineralization, cell population proliferation, centrosome, chondrocyte differentiation involved in endochondral bone morphogenesis, cytoplasm, cytosol, enzyme binding, GTPase activator activity, I-SMAD binding, intramembranous ossification, maintenance of DNA repeat elements, mRNA stabilization, multicellular organism development, negative regulation of canonical Wnt signaling pathway, negative regulation of cell population proliferation, negative regulation of osteoblast differentiation, nucleus
Bgee · 20
AXIN2 → anterior lobe of prostate, body of uterus, cartilage tissue, germinal epithelium, gonad, hair follicle, iris, lamina propria of urinary bladder, mucosa of ileum, Paneth cell, pelvic part of vagina, primary oocyte, primitive streak, prostatic epithelium, right lung, right uterine tube, skin of arm, tail of embryo, thymus, tibialis anterior muscle
RNA expression pattern · 20
AXIN2 → anterior lobe of prostate, body of uterus, cartilage tissue, germinal epithelium, gonad, hair follicle, iris, lamina propria of urinary bladder, mucosa of ileum, Paneth cell, pelvic part of vagina, primary oocyte, primitive streak, prostatic epithelium, right lung, right uterine tube, skin of arm, tail of embryo, thymus, tibialis anterior muscle
related to Function · 7
AXIN2 → APC, AXIN1, Importantly, In, The AXIN, The Axin-related, Wnt
related to Clinical significance · 5
AXIN2 → AXIS, Hypodontia, Mutations, The, The AXIN2
Band · 2
AXIN2 → 11 E1|11 71.83 cM, 17q24.1
Chr. · 2
AXIN2 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
AXIN2 → 108,841,609 bp, 65,561,648 bp
Aliases · 1
AXIN2 → AXIN2, AXIL, ODCRCS, axin 2
BioGPS · 1
AXIN2 → More reference expression data

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Important terminology

gene human bp chr band chromosome 17 protein mouse location beta-catenin axil cancer teeth conductin complex signaling ucsc function external

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
AXIN2AliasesAXIN2, AXIL, ODCRCS, axin 21.00infobox
AXIN2Band17q24.11.00infobox
AXIN2Band11 E1|11 71.83 cM1.00infobox
AXIN2Bgeeskin of arm1.00infobox
AXIN2Bgeebody of uterus1.00infobox
AXIN2Bgeetibialis anterior muscle1.00infobox
AXIN2Bgeethymus1.00infobox
AXIN2Bgeegerminal epithelium1.00infobox
AXIN2Bgeeright lung1.00infobox
AXIN2Bgeemucosa of ileum1.00infobox
AXIN2Bgeeright uterine tube1.00infobox
AXIN2Bgeecartilage tissue1.00infobox
AXIN2Bgeegonad1.00infobox
AXIN2Bgeeprimitive streak1.00infobox
AXIN2Bgeeprimary oocyte1.00infobox
AXIN2Bgeepelvic part of vagina1.00infobox
AXIN2Bgeeprostatic epithelium1.00infobox
AXIN2Bgeehair follicle1.00infobox
AXIN2Bgeeiris1.00infobox
AXIN2BgeePaneth cell1.00infobox
AXIN2Bgeeanterior lobe of prostate1.00infobox
AXIN2Bgeelamina propria of urinary bladder1.00infobox
AXIN2Bgeetail of embryo1.00infobox
AXIN2BioGPSMore reference expression data1.00infobox
AXIN2Chr.Chromosome 17 (human)1.00infobox
AXIN2Chr.Chromosome 11 (mouse)1.00infobox
AXIN2DatabasesNCBI: entry; OMA: entry1.00infobox
AXIN2End65,561,648 bp1.00infobox
AXIN2End108,841,609 bp1.00infobox
AXIN2EnsemblENSG000001686461.00infobox

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