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ATP7A, also known as Menkes' protein (MNK), is a copper-transporting P-type ATPase which uses the energy arising from ATP hydrolysis to transport Cu(I) across cell membranes. The ATP7A protein is a transmembrane protein and is expressed in the intestine and all tissues except liver. In the intestine, ATP7A regulates Cu(I) absorption in the human body by…
Structure, Clinical significance & Interactions
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cu protein gene copper human transport transmembrane cell mutations function bp binding band tissues membrane chr motif disease chromosome also
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| ATP7A | 7.2.2.8 | ↗ | 1.00 | infobox |
| ATP7A | Aliases | ATP7A, DSMAX, MK, MNK, SMAX3, ATPase copper transporting alpha | 1.00 | infobox |
| ATP7A | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AW0, 1KVI, 1KVJ, 1Q8L, 1S6O, 1S6U, 1Y3J, 1Y3K, 1YJR, 1YJT, 1YJU, 1YJV, 2G9O, 2GA7, 2K1R, 2KIJ, 2KMV, 2KMX,… | 1.00 | infobox |
| ATP7A | Band | Xq21.1 | 1.00 | infobox |
| ATP7A | Band | X D|X 47.36 cM | 1.00 | infobox |
| ATP7A | Bgee | buccal mucosa cell | 1.00 | infobox |
| ATP7A | Bgee | trabecular bone | 1.00 | infobox |
| ATP7A | Bgee | skin of thigh | 1.00 | infobox |
| ATP7A | Bgee | germinal epithelium | 1.00 | infobox |
| ATP7A | Bgee | corpus epididymis | 1.00 | infobox |
| ATP7A | Bgee | tibia | 1.00 | infobox |
| ATP7A | Bgee | Achilles tendon | 1.00 | infobox |
| ATP7A | Bgee | parietal pleura | 1.00 | infobox |
| ATP7A | Bgee | visceral pleura | 1.00 | infobox |
| ATP7A | Bgee | skin of hip | 1.00 | infobox |
| ATP7A | Bgee | Epithelium of choroid plexus | 1.00 | infobox |
| ATP7A | Bgee | Rostral migratory stream | 1.00 | infobox |
| ATP7A | Bgee | internal carotid artery | 1.00 | infobox |
| ATP7A | Bgee | choroid plexus of fourth ventricle | 1.00 | infobox |
| ATP7A | Bgee | external carotid artery | 1.00 | infobox |
| ATP7A | Bgee | retinal pigment epithelium | 1.00 | infobox |
| ATP7A | Bgee | vas deferens | 1.00 | infobox |
| ATP7A | Bgee | left lung lobe | 1.00 | infobox |
| ATP7A | Bgee | efferent ductule | 1.00 | infobox |
| ATP7A | Bgee | iris | 1.00 | infobox |
| ATP7A | BioGPS | n/a | 1.00 | infobox |
| ATP7A | Chr. | X chromosome (human) | 1.00 | infobox |
| ATP7A | Chr. | X chromosome (mouse) | 1.00 | infobox |
| ATP7A | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| ATP7A | End | 78,050,395 bp | 1.00 | infobox |
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