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Aplaviroc: Overview, Related Topics & Entities

Aplaviroc (INN, codenamed AK602 and GSK-873140) is a CCR5 entry inhibitor that belongs to a class of 2,5-diketopiperazines developed for the treatment of HIV infection. It was developed by GlaxoSmithKline.

Language: English [EN]
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Aplaviroc topic overview

The analysis highlights Overview, Related Topics and Entities as prominent areas in the source structure around Aplaviroc.

Related topics
7
Source areas
1
Connected nodes
8
Extracted relationships
17
Concept neighborhoods
9
Bridge connections
8

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 7 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
ATC code
none
CAS Number
461443-59-4 Y · HCl: 461023-63-2 Y
ChEMBL
ChEMBL1255794
ChemSpider
2272720 Y
CompTox Dashboard (EPA)
DTXSID6047317

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Aplaviroc connects Entity context

The extracted context around Aplaviroc shows recurring relationship patterns in the source. For example, Aplaviroc → 461443-59-4 Y, HCl: 461023-63-2 Y Another extracted example is Aplaviroc → 98B425P30V, HCl: 04D148Z3VR Y. Use these groups to spot repeated connection types before inspecting the individual relationships.

Aplaviroc

Top relations

CAS Number · 2
Aplaviroc → 461443-59-4 Y, HCl: 461023-63-2 Y
UNII · 2
Aplaviroc → 98B425P30V, HCl: 04D148Z3VR Y
3D model (JSmol) · 1
Aplaviroc → Interactive image
ATC code · 1
Aplaviroc → none
ChEMBL · 1
Aplaviroc → ChEMBL1255794
ChemSpider · 1
Aplaviroc → 2272720 Y
CompTox Dashboard (EPA) · 1
Aplaviroc → DTXSID6047317
DrugBank · 1
Aplaviroc → DB06497 Y
Formula · 1
Aplaviroc → C33H43N3O6
IUPHAR/BPS · 1
Aplaviroc → 805

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

developed discontinued development ccr5 inn hiv glaxosmithkline codenamed ak602 gsk-873140 entry inhibitor belongs class 5-diketopiperazines treatment infection october 2005 studies

Aplaviroc relationships Subject–Predicate–Object triples

TTTA extracted 17 structured relationships around Aplaviroc. Examples in this analysis include Aplaviroc → 3D model (JSmol) → Interactive image and Aplaviroc → ATC code → none. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Aplaviroc3D model (JSmol)Interactive image1.00infobox
AplavirocATC codenone1.00infobox
AplavirocCAS Number461443-59-4 Y1.00infobox
AplavirocCAS NumberHCl: 461023-63-2 Y1.00infobox
AplavirocChEMBLChEMBL12557941.00infobox
AplavirocChemSpider2272720 Y1.00infobox
AplavirocCompTox Dashboard (EPA)DTXSID60473171.00infobox
AplavirocDrugBankDB06497 Y1.00infobox
AplavirocFormulaC33H43N3O61.00infobox
AplavirocIUPHAR/BPS8051.00infobox
AplavirocKEGGD06557 Y1.00infobox
AplavirocLegal statusDevelopment terminated1.00infobox
AplavirocMolar mass577.722 g·mol−11.00infobox
AplavirocPubChem CID30013221.00infobox
AplavirocRoutes of administrationOral1.00infobox
AplavirocUNII98B425P30V1.00infobox
AplavirocUNIIHCl: 04D148Z3VR Y1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Aplaviroc bring nearby vocabulary together. In this analysis, examples include Ccr5, Development and Discontinued. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Aplaviroc
    • Ccr5
    • Development
    • Discontinued
    • Authors
    • Belongs
    • Claimed
    • Class
    • Codenamed
    • Concerns
    • Due
    • Efficacy
    • Entry
  • aplaviroc
    • Ccr5
    • Development
    • Discontinued
    • Authors
    • Belongs
    • Claimed
    • Class
    • Codenamed
    • Concerns
    • Due
    • Efficacy
    • Entry
  • 2,5-diketopiperazines
    • Ak602
    • Belongs
    • Class
    • Codenamed
    • Entry
    • Gsk-873140
    • Hiv
    • Infection
    • Inhibitor
    • Inn
    • Treatment
    • Ccr5
  • ccr5
    • Belongs
    • Class
    • Codenamed
    • Entry
    • Gsk-873140
    • Hiv
    • Infection
    • Inhibitor
    • Inn
    • Treatment
    • Developed
    • Development
  • entry inhibitor
    • Belongs
    • Class
    • Gsk-873140
    • Hiv
    • Infection
    • Inhibitor
    • Inn
    • Treatment
    • Developed
  • liver toxicity
    • Concerns
    • Due
    • Liver
    • October
    • Studies
    • Toxicity
    • Discontinued
    • Aplaviroc
  • hiv
    • Infection
    • Inhibitor
    • Inn
    • Treatment
  • inn
    • Hiv
    • Infection
    • Treatment

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the Aplaviroc map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

Aplaviroc

Nodes9
Edges8
Triples17
Avg. degree1.78
Density0.222222
Components1

Source & methodology

TTTA analyzes the structure around Aplaviroc to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Related Topics & Entities, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Aplaviroc · EN edition · Analysis: TopicsToTalkAbout

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