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ADAMTS2

A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAM-TS2) also known as procollagen I N-proteinase (PC I-NP) is an enzyme that in humans is encoded by the ADAMTS2 gene.

Function, Gene & Clinical significance

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Function

4 related topics

Gene

2 related topics

Clinical significance

2 related topics

Overview

2 related topics

Key facts & relationships

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3.4.24.14
Aliases
ADAMTS2, ADAM-TS2, ADAMTS-2, ADAMTS-3, NPI, PC I-NP, PCI-NP, PCINP, PCPNI, PNPI, ADAM metallopeptidase with thrombospondin type 1 motif 2, EDSDERMS
Band
11|11 B1.3
Bgee
stromal cell of endometrium · subcutaneous adipose tissue · right lung · right coronary artery · spleen
BioGPS
n/a
Chr.
Chromosome 11 (mouse)

Topics to explore

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Overview

Gene

Function

Clinical significance

Advanced semantic analysis

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Map overview Semantic statistics

ADAMTS2

Nodes15
Edges14
Triples89
Avg. degree1.87
Density0.133333
Components1

How this topic connects Entity context

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ADAMTS2

Top relations

Bgee · 20
ADAMTS2 → ankle, aortic valve, ascending aorta, body of femur, cervix, decidua, gastric mucosa, gastrula, left coronary artery, left uterine tube, myometrium, right coronary artery, right lung, spleen, stroma of bone marrow, stromal cell of endometrium, subcutaneous adipose tissue, umbilical cord, upper lobe of left lung, vas deferens
RNA expression pattern · 20
ADAMTS2 → ankle, aortic valve, ascending aorta, body of femur, cervix, decidua, gastric mucosa, gastrula, left coronary artery, left uterine tube, myometrium, right coronary artery, right lung, spleen, stroma of bone marrow, stromal cell of endometrium, subcutaneous adipose tissue, umbilical cord, upper lobe of left lung, vas deferens
Gene ontology · 16
ADAMTS2 → collagen catabolic process, collagen fibril organization, collagen-containing extracellular matrix, extracellular matrix, extracellular region, hydrolase activity, lung development, metal ion binding, metalloendopeptidase activity, metallopeptidase activity, peptidase activity, protein processing, proteolysis, skin development, spermatogenesis, zinc ion binding
related to Clinical significance · 7
ADAMTS2 → As, Cross-links, Danlos, Ehlers, Procollagen, Several, These
related to External links · 4
ADAMTS2 → Deprecated, GeneCardThe MEROPS, M12, UCSC Genome Browser
related to Function · 3
ADAMTS2 → Procollagens, Specifically, This
3.4.24.14 · 1
ADAMTS2 → ↗
Aliases · 1
ADAMTS2 → ADAMTS2, ADAM-TS2, ADAMTS-2, ADAMTS-3, NPI, PC I-NP, PCI-NP, PCINP, PCPNI, PNPI, ADAM metallopeptidase with thrombospondin type 1 motif 2, EDSDERMS
Band · 1
ADAMTS2 → 11|11 B1.3
BioGPS · 1
ADAMTS2 → n/a

Important terminology Word statistics

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Important terminology

gene enzyme procollagen bp also collagen chr function location chromosome mutations mouse band end thrombospondin adam-ts2 pc i-np external fibrils

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ADAMTS23.4.24.141.00infobox
ADAMTS2AliasesADAMTS2, ADAM-TS2, ADAMTS-2, ADAMTS-3, NPI, PC I-NP, PCI-NP, PCINP, PCPNI, PNPI, ADAM metallopeptidase with thrombospondin type 1 motif 2, EDSDERMS1.00infobox
ADAMTS2Band11|11 B1.31.00infobox
ADAMTS2Bgeestromal cell of endometrium1.00infobox
ADAMTS2Bgeesubcutaneous adipose tissue1.00infobox
ADAMTS2Bgeeright lung1.00infobox
ADAMTS2Bgeeright coronary artery1.00infobox
ADAMTS2Bgeespleen1.00infobox
ADAMTS2Bgeeleft coronary artery1.00infobox
ADAMTS2Bgeeupper lobe of left lung1.00infobox
ADAMTS2Bgeegastric mucosa1.00infobox
ADAMTS2Bgeemyometrium1.00infobox
ADAMTS2Bgeeleft uterine tube1.00infobox
ADAMTS2Bgeeascending aorta1.00infobox
ADAMTS2Bgeeaortic valve1.00infobox
ADAMTS2Bgeedecidua1.00infobox
ADAMTS2Bgeegastrula1.00infobox
ADAMTS2Bgeeumbilical cord1.00infobox
ADAMTS2Bgeestroma of bone marrow1.00infobox
ADAMTS2Bgeebody of femur1.00infobox
ADAMTS2Bgeeankle1.00infobox
ADAMTS2Bgeecervix1.00infobox
ADAMTS2Bgeevas deferens1.00infobox
ADAMTS2BioGPSn/a1.00infobox
ADAMTS2Chr.Chromosome 11 (mouse)1.00infobox
ADAMTS2DatabasesNCBI: entry1.00infobox
ADAMTS2End50,698,400 bp1.00infobox
ADAMTS2Ensembln/a1.00infobox
ADAMTS2Entrez95091.00infobox
ADAMTS2Enzyme activityEnzyme activityEC #BRENDAExPASyKEGGMetaCyc3.4.24.14↗↗↗↗1.00infobox

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