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Explore the main themes, entities and connections around AARS1. Start with the topic map, then use the sections below for research and deeper semantic analysis.
Explore this topic
Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.
Clinical significance
23 related topics
Overview
3 related topics
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
- 6.1.1.7
- ↗
- Aliases
- AARS1, CMT2N, EIEE29, alanyl-tRNA synthetase, AARS, alanyl-tRNA synthetase 1, DEE29, TTD8, HDLS2
- Available structures
- Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4XEO, 4XEM
- Band
- 16q22.1 · 8|8 E1
- Bgee
- beta cell · frontal pole · Brodmann area 10 · right frontal lobe · middle frontal gyrus
- BioGPS
- n/a
Topics to explore
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.Browse the full topic structure. Each item opens a new analysis centered on that subject.
Overview
- Enzyme
- Gene
- Aminoacyl-tRNA synthetases Aminoacyl tRNA synthetase
Clinical significance
- Charcot-Marie-Tooth Disease Charcot–Marie–Tooth disease
- Neuropathy Peripheral neuropathy
- GARS1 Glycine—tRNA ligase
- HARS1 HARS
- WARS1 WARS (gene)
- YARS1 YARS
- Amino acids Amino acid
- Helical Alpha helix
- Cytoplasmic Cytoplasm
- TRNA Transfer RNA
- Protein synthesis Protein biosynthesis
- Mutations Mutation
- Non-photosensitive trichothiodystrophy Trichothiodystrophy
- Hereditary Heredity
- Neurodevelopmental disorder
- Sulfur
- Hair
- Nails Nail (anatomy)
- Skin
- Photosensitive Photosensitivity
- Aging Ageing
- Methionyl-tRNA synthetase Methionine—tRNA ligase
- Protein translation Translation (biology)
Advanced semantic analysis
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
Map overview Semantic statistics
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.AARS1
Nodes29
Edges28
Triples115
Avg. degree1.93
Density0.068966
Components1
How this topic connects Entity context
Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.See the strongest relationship patterns around the current topic before diving into the raw triples.
AARS1
Top relations
Gene ontology · 32
AARS1 → alanine-tRNA ligase activity, alanyl-tRNA aminoacylation, amino acid binding, aminoacyl-tRNA editing activity, aminoacyl-tRNA ligase activity, aminoacyl-tRNA metabolism involved in translational fidelity, ATP binding, cerebellar Purkinje cell layer development, cytoplasm, cytosol, extracellular exosome, ligase activity, membrane, metal ion binding, mitochondrion, negative regulation of neuron apoptotic process, neuromuscular process, neuromuscular process controlling balance, nucleic acid binding, nucleotide binding
Bgee · 20
AARS1 → anterior horn of spinal cord, beta cell, Brodmann area 10, Brodmann area 9, calvaria, cerebellar vermis, cingulate gyrus, crypt of lieberkuhn of small intestine, endothelial cell of lymphatic vessel, facial motor nucleus, frontal pole, lacrimal gland, left lobe of liver, middle frontal gyrus, paraflocculus of cerebellum, primitive streak, right frontal lobe, somite, stroma of bone marrow, stromal cell of endometrium
RNA expression pattern · 20
AARS1 → anterior horn of spinal cord, beta cell, Brodmann area 10, Brodmann area 9, calvaria, cerebellar vermis, cingulate gyrus, crypt of lieberkuhn of small intestine, endothelial cell of lymphatic vessel, facial motor nucleus, frontal pole, lacrimal gland, left lobe of liver, middle frontal gyrus, paraflocculus of cerebellum, primitive streak, right frontal lobe, somite, stroma of bone marrow, stromal cell of endometrium
related to Charcot-Marie-Tooth Disease · 9
AARS1 → Charcot-Marie-Tooth Disease, CMT2, GARS1, HARS1, In AARS1, Mutations, This, WARS1, YARS1
related to Trichothiodystrophy · 9
AARS1 → CMT2, In, NPS-TTD, PS-TTD, Research, These, Trichothiodystrophy, TTD, Unlike
Band · 2
AARS1 → 16q22.1, 8|8 E1
Chr. · 2
AARS1 → Chromosome 16 (human), Chromosome 8 (mouse)
End · 2
AARS1 → 111,784,296 bp, 70,289,707 bp
6.1.1.7 · 1
AARS1 → ↗
Aliases · 1
AARS1 → AARS1, CMT2N, EIEE29, alanyl-tRNA synthetase, AARS, alanyl-tRNA synthetase 1, DEE29, TTD8, HDLS2
Important terminology Word statistics
Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
Important terminology
bp gene chr human 16 band trna chromosome mutations synthetase aminoacyl-trna location enzyme trichothiodystrophy mouse enzymes amino protein cmt2 genes
Entity relationships Subject–Predicate–Object triples
Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| AARS1 | 6.1.1.7 | ↗ | 1.00 | infobox |
| AARS1 | Aliases | AARS1, CMT2N, EIEE29, alanyl-tRNA synthetase, AARS, alanyl-tRNA synthetase 1, DEE29, TTD8, HDLS2 | 1.00 | infobox |
| AARS1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4XEO, 4XEM | 1.00 | infobox |
| AARS1 | Band | 16q22.1 | 1.00 | infobox |
| AARS1 | Band | 8|8 E1 | 1.00 | infobox |
| AARS1 | Bgee | beta cell | 1.00 | infobox |
| AARS1 | Bgee | frontal pole | 1.00 | infobox |
| AARS1 | Bgee | Brodmann area 10 | 1.00 | infobox |
| AARS1 | Bgee | right frontal lobe | 1.00 | infobox |
| AARS1 | Bgee | middle frontal gyrus | 1.00 | infobox |
| AARS1 | Bgee | paraflocculus of cerebellum | 1.00 | infobox |
| AARS1 | Bgee | Brodmann area 9 | 1.00 | infobox |
| AARS1 | Bgee | stromal cell of endometrium | 1.00 | infobox |
| AARS1 | Bgee | cingulate gyrus | 1.00 | infobox |
| AARS1 | Bgee | cerebellar vermis | 1.00 | infobox |
| AARS1 | Bgee | calvaria | 1.00 | infobox |
| AARS1 | Bgee | left lobe of liver | 1.00 | infobox |
| AARS1 | Bgee | facial motor nucleus | 1.00 | infobox |
| AARS1 | Bgee | lacrimal gland | 1.00 | infobox |
| AARS1 | Bgee | stroma of bone marrow | 1.00 | infobox |
| AARS1 | Bgee | anterior horn of spinal cord | 1.00 | infobox |
| AARS1 | Bgee | endothelial cell of lymphatic vessel | 1.00 | infobox |
| AARS1 | Bgee | somite | 1.00 | infobox |
| AARS1 | Bgee | primitive streak | 1.00 | infobox |
| AARS1 | Bgee | crypt of lieberkuhn of small intestine | 1.00 | infobox |
| AARS1 | BioGPS | n/a | 1.00 | infobox |
| AARS1 | Chr. | Chromosome 16 (human) | 1.00 | infobox |
| AARS1 | Chr. | Chromosome 8 (mouse) | 1.00 | infobox |
| AARS1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| AARS1 | End | 70,289,707 bp | 1.00 | infobox |
No triples extracted yet.
Related concept clusters Concept neighborhoods
Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.These clusters group vocabulary that occurs around closely connected concepts in the source material.
Connections between topic areas Semantic bridges
Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.
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