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Amino acid replacement

Amino acid replacement is a change from one amino acid to a different amino acid in a protein due to point mutation in the corresponding DNA sequence. It is caused by a nonsynonymous missense mutation which changes the codon sequence to code for a different amino acid than the original sequence.

Conservative and radical replacements, Physicochemical distances & Tendency to undergo amino acid replacement

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Conservative and radical replacements

Substitution matricesPhysico-chemical distanceAmino acid chemical propertiesConservative replacementProtein structure
8 related topics

Physicochemical distances

LeucineIsoleucineCysteine
3 related topics

Tendency to undergo amino acid replacement

Methionine
1 related topics

Overview

Amino acidPoint mutationNonsynonymousMissense mutation
4 related topics

Topics to explore

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Overview

Conservative and radical replacements

Physicochemical distances

Tendency to undergo amino acid replacement

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Amino acid replacement

Nodes21
Edges20
Triples31
Avg. degree1.9
Density0.095238
Components1

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Amino acid replacement

Top relations

related to Patterns of amino acid replacement · 8
Amino acid replacement → Also, Conservative, DNA, Evolution, Most, On, Smaller, Therefore
related to Tendency to undergo amino acid replacement · 8
Amino acid replacement → Based, Example, Grantham's, Graur's Stability Index, One, Some, Stability, The
related to Conservative and radical replacements · 7
Amino acid replacement → Conservative, Not, Radical, Similarity, The, This, Usually
related to Typical and idiosyncratic amino acids · 6
Amino acid replacement → Amino, Idiosyncratic, In, Leucine, Tryptophan, Typical
is a · 1
Amino acid replacement → change from one amino acid to a different amino acid in a protein due to point mutation in the corresponding DNA sequence

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Important terminology

amino acids acid distance properties protein physicochemical based different replacement replaced replacements index similar difference structure substitution exchanged polarity mutation

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Amino acid replacementis achange from one amino acid to a different amino acid in a protein due to point mutation in the corresponding DNA sequence0.90text
amino acid size or chargeinstance ofor simple properties0.80text
Amino acid replacementrelated to Conservative and radical replacementsNot0.60section
Amino acid replacementrelated to Conservative and radical replacementsThe0.60section
Amino acid replacementrelated to Conservative and radical replacementsSimilarity0.60section
Amino acid replacementrelated to Conservative and radical replacementsUsually0.60section
Amino acid replacementrelated to Conservative and radical replacementsConservative0.60section
Amino acid replacementrelated to Conservative and radical replacementsThis0.60section
Amino acid replacementrelated to Conservative and radical replacementsRadical0.60section
Amino acid replacementrelated to Patterns of amino acid replacementEvolution0.60section
Amino acid replacementrelated to Patterns of amino acid replacementDNA0.60section
Amino acid replacementrelated to Patterns of amino acid replacementMost0.60section

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