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LAT

LAT (z anglického linker for activation of T cells) je adaptorový protein zapojený do časné aktivace a vývoje T-lymfocytů. Je exprimován T-lymfocyty, NK buňkami, žírnými buňkami i megakaryocyty . Lidský LAT protein je kódovaný stejnojmenným genem LAT na chromosomu 16. Vlivem alternativního sestřihu dochází ke vzniku několika transkripčních variant…

Funkce, Signalizace & LAT Defekty

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Overview

Funkce

Struktura

Signalizace

LAT Defekty

Advanced semantic analysis

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Map overview Semantic statistics

LAT

Nodes52
Edges51
Triples55
Avg. degree1.96
Density0.038462
Components1

How this topic connects Entity context

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LAT

Top relations

related to Signalizace · 19
LAT → Aktivovaná Lck, Aktivovaná ZAP-70, Fyn, Gads, Grb2, ITAM, Lck, MHC, Na, Na SH3, Následně, PIP2, PLC-γ, Signální, SLP-76, Src, T-buněčným, T-lymfocytu, ZAP-70
related to Funkce · 17
LAT → Aktivace T-buněčného, CD2, CD28, CD58, CD9, Funkce LAT, Grb2, Jsou-li, Molekuly CD5, Na, Protein LAT, SH2, Syk, T-buněčné, T-lymfocytů, Vazba, ZAP-70
related to LAT Defekty · 10
LAT → B-lymfocytů, Byly, CD4, CD8, Další, Mutace, NK, Pacienti, T-lymfocytů, Th2
related to Struktura · 9
LAT → Cys26, Cys29, Extracelulární, III, Intracelulární, Lidský LAT, T-lymfocytů, Transmembránová, Význam

Important terminology Word statistics

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Important terminology

protein t-lymfocytů fosforylované adaptorový signální rodiny molekuly část 171 191 proteinu váže aktivace zap-70 grb2 tyrosiny zbytky receptoru adaptorové proteiny

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
LATrelated to FunkceProtein LAT0.60section
LATrelated to FunkceJsou-li0.60section
LATrelated to FunkceSH20.60section
LATrelated to FunkceFunkce LAT0.60section
LATrelated to FunkceAktivace T-buněčného0.60section
LATrelated to FunkceZAP-700.60section
LATrelated to FunkceSyk0.60section
LATrelated to FunkceNa0.60section
LATrelated to FunkceGrb20.60section
LATrelated to FunkceVazba0.60section
LATrelated to FunkceCD580.60section
LATrelated to FunkceCD20.60section

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