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Erythromycin

Erythromycin je významné makrolidové antibiotikum vyvinuté v roce 1952 společností Eli Lilly. Je účinný především proti aerobním grampozitivním kokům a bacilům – např. stafylokokům a streptokokům či tyčkám z rodu Clostridium či Listeria.

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Key facts & relationships

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Cesty podání
ústní podání, infuze a Topické podanie
ChEMBL ID
CHEMBL532
ChemSpider ID
12041
InChI
InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18…
Indikace
legionelóza, Chlamydióza, měkký vřed, erythrasma, Uretritida, kapavka, gastroenteritida, akné, kampylobakterióza, černý kašel, staphylococcal infection a anthrax
Klasifikace ATC
D10AF02 J01FA01 S01AA17 QJ51FA01

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Overview

Účinek

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Map overview Semantic statistics

Erythromycin

Nodes18
Edges17
Triples15
Avg. degree1.89
Density0.111111
Components1

How this topic connects Entity context

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Erythromycin

Top relations

related to Externí odkazy · 2
Erythromycin → Obrázky, Wikimedia Commons
Cesty podání · 1
Erythromycin → ústní podání, infuze a Topické podanie
ChEMBL ID · 1
Erythromycin → CHEMBL532
ChemSpider ID · 1
Erythromycin → 12041
InChI · 1
Erythromycin → InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18…
Indikace · 1
Erythromycin → legionelóza, Chlamydióza, měkký vřed, erythrasma, Uretritida, kapavka, gastroenteritida, akné, kampylobakterióza, černý kašel, staphylococcal infection a anthrax
Klasifikace ATC · 1
Erythromycin → D10AF02 J01FA01 S01AA17 QJ51FA01
Molární hmotnost · 1
Erythromycin → 733,93 g/mol
Název (INN) · 1
Erythromycin → Erythromycin
Název podle IUPAC · 1
Erythromycin → (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6- {[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}- 14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)- 5-hydroxy-4-methoxy-4,6…

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Important terminology

datové položky 1952 aerobním grampozitivním kokům bacilům stafylokokům streptokokům clostridium listeria inhibuje významné makrolidové antibiotikum vyvinuté roce společností eli lilly

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ErythromycinCesty podáníústní podání, infuze a Topické podanie1.00infobox
ErythromycinChEMBL IDCHEMBL5321.00infobox
ErythromycinChemSpider ID120411.00infobox
ErythromycinInChIInChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18…1.00infobox
ErythromycinIndikacelegionelóza, Chlamydióza, měkký vřed, erythrasma, Uretritida, kapavka, gastroenteritida, akné, kampylobakterióza, černý kašel, staphylococcal infection a anthrax1.00infobox
ErythromycinKlasifikace ATCD10AF02 J01FA01 S01AA17 QJ51FA011.00infobox
ErythromycinMolární hmotnost733,93 g/mol1.00infobox
ErythromycinNázev (INN)Erythromycin1.00infobox
ErythromycinNázev podle IUPAC(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6- {[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}- 14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)- 5-hydroxy-4-methoxy-4,6…1.00infobox
ErythromycinPubChem125601.00infobox
ErythromycinSMILESCCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O1.00infobox
ErythromycinSumární vzorecC37H67NO131.00infobox
ErythromycinČíslo CAS114-07-81.00infobox

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