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ZNF703

ZNF703 is a gene which has been linked with the development of breast cancers. ZNF703 is contained within the NET/N1z family responsible for regulation of transcription essential for developmental growth especially in the hindbrain. Normal functions performed by ZNF703 include adhesion, movement and proliferation of cells. ZNF703 directly accumulates…

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Role in cancer

5 related topics

Location

2 related topics

Discovery

1 related topics

Resistance to drugs

1 related topics

Key facts & relationships

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Aliases
ZNF703, ZEPPO1, ZNF503L, ZPO1, NLZ1, zinc finger protein 703
Band
8p11.23 · 8|8 A2
Bgee
skin of arm · nipple · muscle of thigh · gastrocnemius muscle · body of tongue
BioGPS
n/a
Chr.
Chromosome 8 (human) · Chromosome 8 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Discovery

Location

Role in cancer

Resistance to drugs

Advanced semantic analysis

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Map overview Semantic statistics

ZNF703

Nodes20
Edges19
Triples104
Avg. degree1.9
Density0.1
Components1

How this topic connects Entity context

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ZNF703

Top relations

Gene ontology · 21
ZNF703 → adherens junction assembly, cellular response to estradiol stimulus, cytoplasm, mammary gland epithelial cell differentiation, metal ion binding, negative regulation of homotypic cell-cell adhesion, negative regulation of transcription, DNA-templated, nuclear matrix, nucleic acid binding, nucleus, positive regulation of cell migration, positive regulation of cell population proliferation, positive regulation of epithelial to mesenchymal transition, positive regulation of mammary gland epithelial cell proliferation, protein binding, protein-containing complex, regulation of canonical Wnt signaling pathway, regulation of cell cycle, regulation of transcription, DNA-templated, regulation of transforming growth factor beta receptor signaling pathway
Bgee · 20
ZNF703 → adrenal gland, ankle, ankle joint, body of tongue, brown adipose tissue, external carotid artery, gastrocnemius muscle, hair follicle, internal carotid artery, lip, mucosa of transverse colon, muscle of thigh, nipple, popliteal artery, pylorus, Skeletal muscle tissue of rectus abdominis, skin of arm, skin of external ear, tibial arteries, transitional epithelium of urinary bladder
RNA expression pattern · 20
ZNF703 → adrenal gland, ankle, ankle joint, body of tongue, brown adipose tissue, external carotid artery, gastrocnemius muscle, hair follicle, internal carotid artery, lip, mucosa of transverse colon, muscle of thigh, nipple, popliteal artery, pylorus, Skeletal muscle tissue of rectus abdominis, skin of arm, skin of external ear, tibial arteries, transitional epithelium of urinary bladder
related to Role in cancer · 9
ZNF703 → As, CD49F, DCAF7, Gene, NCRO2, PHB2, RNA SPRY4-It1, The ZNF703, Typically
related to Resistance to drugs · 5
ZNF703 → As, Half, Overexpression, Tamoxifen, The
is a · 3
ZNF703 → gene which has been linked with the development of breast cancers, part of 8p12 telomeric amplicon that is associated with Luminal B breast cancer, target for therapeutic medicines since survival rates increase as transcription rates decrease
related to Discovery · 3
ZNF703 → Amplification, Researchers, The
Band · 2
ZNF703 → 8p11.23, 8|8 A2
Chr. · 2
ZNF703 → Chromosome 8 (human), Chromosome 8 (mouse)
End · 2
ZNF703 → 27,471,489 bp, 37,700,019 bp

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Important terminology

gene cancer chromosome bp tamoxifen human 8p12 luminal transcription chr band cells patients location resistance regulation growth region associated expression

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ZNF703AliasesZNF703, ZEPPO1, ZNF503L, ZPO1, NLZ1, zinc finger protein 7031.00infobox
ZNF703Band8p11.231.00infobox
ZNF703Band8|8 A21.00infobox
ZNF703Bgeeskin of arm1.00infobox
ZNF703Bgeenipple1.00infobox
ZNF703Bgeemuscle of thigh1.00infobox
ZNF703Bgeegastrocnemius muscle1.00infobox
ZNF703Bgeebody of tongue1.00infobox
ZNF703BgeeSkeletal muscle tissue of rectus abdominis1.00infobox
ZNF703Bgeepopliteal artery1.00infobox
ZNF703Bgeetibial arteries1.00infobox
ZNF703Bgeemucosa of transverse colon1.00infobox
ZNF703Bgeepylorus1.00infobox
ZNF703Bgeeankle joint1.00infobox
ZNF703Bgeeankle1.00infobox
ZNF703Bgeetransitional epithelium of urinary bladder1.00infobox
ZNF703Bgeeinternal carotid artery1.00infobox
ZNF703Bgeelip1.00infobox
ZNF703Bgeeexternal carotid artery1.00infobox
ZNF703Bgeeadrenal gland1.00infobox
ZNF703Bgeehair follicle1.00infobox
ZNF703Bgeeskin of external ear1.00infobox
ZNF703Bgeebrown adipose tissue1.00infobox
ZNF703BioGPSn/a1.00infobox
ZNF703Chr.Chromosome 8 (human)1.00infobox
ZNF703Chr.Chromosome 8 (mouse)1.00infobox
ZNF703DatabasesNCBI: entry; OMA: entry1.00infobox
ZNF703End37,700,019 bp1.00infobox
ZNF703End27,471,489 bp1.00infobox
ZNF703EnsemblENSG000001837791.00infobox

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