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WNK2

Serine/threonine-protein kinase WNK2 is an enzyme that in humans is encoded by the WNK2 gene.

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2.7.11.1
Aliases
WNK2, NY-CO-43, P/OKcl.13, PRKSDCCAG43, WNK lysine deficient protein kinase 2
Band
9q22.31 · 13 A5|13 25.07 cM
Bgee
apex of heart · right uterine tube · right auricle of heart · right hemisphere of cerebellum · body of pancreas
BioGPS
n/a
Chr.
Chromosome 9 (human) · Chromosome 13 (mouse)

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WNK2

Nodes4
Edges3
Triples87
Avg. degree1.5
Density0.5
Components1

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WNK2

Top relations

Gene ontology · 24
WNK2 → ATP binding, chloride channel inhibitor activity, cytoplasm, cytosol, intracellular signal transduction, ion homeostasis, kinase activity, membrane, negative regulation of cell population proliferation, negative regulation of ERK1 and ERK2 cascade, negative regulation of sodium ion transport, nucleotide binding, phosphorylation, plasma membrane, positive regulation of canonical Wnt signaling pathway, positive regulation of ion transmembrane transporter activity, positive regulation of potassium ion import across plasma membrane, positive regulation of sodium ion transmembrane transporter activity, potassium channel inhibitor activity, protein autophosphorylation
Bgee · 20
WNK2 → anterior pituitary, apex of heart, body of pancreas, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, ganglionic eminence, lacrimal gland, left ventricle, muscle layer of sigmoid colon, muscle of thigh, primary visual cortex, right auricle of heart, right hemisphere of cerebellum, right uterine tube, Rostral migratory stream, secondary oocyte, skeletal muscle tissue, superior frontal gyrus, transverse colon, triceps brachii muscle
RNA expression pattern · 20
WNK2 → anterior pituitary, apex of heart, body of pancreas, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, ganglionic eminence, lacrimal gland, left ventricle, muscle layer of sigmoid colon, muscle of thigh, primary visual cortex, right auricle of heart, right hemisphere of cerebellum, right uterine tube, Rostral migratory stream, secondary oocyte, skeletal muscle tissue, superior frontal gyrus, transverse colon, triceps brachii muscle
Band · 2
WNK2 → 13 A5|13 25.07 cM, 9q22.31
Chr. · 2
WNK2 → Chromosome 13 (mouse), Chromosome 9 (human)
End · 2
WNK2 → 49,301,490 bp, 93,320,572 bp
2.7.11.1 · 1
WNK2 → ↗
Aliases · 1
WNK2 → WNK2, NY-CO-43, P/OKcl.13, PRKSDCCAG43, WNK lysine deficient protein kinase 2
BioGPS · 1
WNK2 → n/a
Databases · 1
WNK2 → NCBI: entry; OMA: entry

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Important terminology

gene kinase bp chr human band protein location chromosome lysine activity 13 encoded conserved subdomain enzyme mouse serine 320 572

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
WNK22.7.11.11.00infobox
WNK2AliasesWNK2, NY-CO-43, P/OKcl.13, PRKSDCCAG43, WNK lysine deficient protein kinase 21.00infobox
WNK2Band9q22.311.00infobox
WNK2Band13 A5|13 25.07 cM1.00infobox
WNK2Bgeeapex of heart1.00infobox
WNK2Bgeeright uterine tube1.00infobox
WNK2Bgeeright auricle of heart1.00infobox
WNK2Bgeeright hemisphere of cerebellum1.00infobox
WNK2Bgeebody of pancreas1.00infobox
WNK2Bgeetransverse colon1.00infobox
WNK2Bgeeanterior pituitary1.00infobox
WNK2Bgeeganglionic eminence1.00infobox
WNK2Bgeeleft ventricle1.00infobox
WNK2Bgeemuscle layer of sigmoid colon1.00infobox
WNK2Bgeemuscle of thigh1.00infobox
WNK2Bgeesuperior frontal gyrus1.00infobox
WNK2Bgeeprimary visual cortex1.00infobox
WNK2Bgeecerebellar cortex1.00infobox
WNK2Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
WNK2Bgeesecondary oocyte1.00infobox
WNK2Bgeeskeletal muscle tissue1.00infobox
WNK2Bgeelacrimal gland1.00infobox
WNK2BgeeRostral migratory stream1.00infobox
WNK2Bgeetriceps brachii muscle1.00infobox
WNK2BioGPSn/a1.00infobox
WNK2Chr.Chromosome 9 (human)1.00infobox
WNK2Chr.Chromosome 13 (mouse)1.00infobox
WNK2DatabasesNCBI: entry; OMA: entry1.00infobox
WNK2End93,320,572 bp1.00infobox
WNK2End49,301,490 bp1.00infobox

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