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Uramustine

Uramustine (INN) or uracil mustard is a chemotherapy drug which belongs to the class of alkylating agents. It is used in lymphatic malignancies such as non-Hodgkin's lymphoma. It works by damaging DNA, primarily in cancer cells that preferentially take up the uracil due to their need to make nucleic acids during their rapid cycles of cell division. The…

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Key facts & relationships

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3D model (JSmol)
Interactive image
ATC code
L01AD08 (WHO)
CAS Number
66-75-1 Y
ChEMBL
ChEMBL1488 N
ChemSpider
5959 N
CompTox Dashboard (EPA)
DTXSID8026270

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Overview

Advanced semantic analysis

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Map overview Semantic statistics

Uramustine

Nodes16
Edges15
Triples17
Avg. degree1.88
Density0.125
Components1

How this topic connects Entity context

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Uramustine

Top relations

3D model (JSmol) · 1
Uramustine → Interactive image
ATC code · 1
Uramustine → L01AD08 (WHO)
CAS Number · 1
Uramustine → 66-75-1 Y
ChEMBL · 1
Uramustine → ChEMBL1488 N
ChemSpider · 1
Uramustine → 5959 N
CompTox Dashboard (EPA) · 1
Uramustine → DTXSID8026270
DrugBank · 1
Uramustine → DB00791 N
ECHA InfoCard · 1
Uramustine → 100.000.574
Excretion · 1
Uramustine → Renal
Formula · 1
Uramustine → C8H11Cl2N3O2

Important terminology Word statistics

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Important terminology

uracil dna mustard cells inn chemotherapy drug lymphatic cancer apoptosis belongs class alkylating agents used malignancies non-hodgkin's lymphoma works damaging

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Uramustine3D model (JSmol)Interactive image1.00infobox
UramustineATC codeL01AD08 (WHO)1.00infobox
UramustineCAS Number66-75-1 Y1.00infobox
UramustineChEMBLChEMBL1488 N1.00infobox
UramustineChemSpider5959 N1.00infobox
UramustineCompTox Dashboard (EPA)DTXSID80262701.00infobox
UramustineDrugBankDB00791 N1.00infobox
UramustineECHA InfoCard100.000.5741.00infobox
UramustineExcretionRenal1.00infobox
UramustineFormulaC8H11Cl2N3O21.00infobox
UramustineIUPHAR/BPS76211.00infobox
UramustineKEGGD06265 Y1.00infobox
UramustineMolar mass252.10 g·mol−11.00infobox
UramustineProtein binding5%1.00infobox
UramustinePubChem CID61941.00infobox
UramustineUNIIW7KQ46GJ8U1.00infobox

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