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TYMP

TYMP is a gene that encodes for the enzyme thymidine phosphorylase. The TYMP gene is also known as ECGF1 (endothelial cell growth factor 1, platelet-derived) and MNGIE due to its role in MNGIE syndrome.

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2.4.2.4
Aliases
TYMP, thymidine phosphorylase, ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1UOU, 2J0F, 2WK5, 2WK6
Band
22q13.33 · 15 E3|15 44.86 cM
Bgee
right uterine tube · granulocyte · monocyte · right lung · upper lobe of left lung
BioGPS
More reference expression data

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Map overview Semantic statistics

TYMP

Nodes8
Edges7
Triples96
Avg. degree1.75
Density0.25
Components1

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TYMP

Top relations

Gene ontology · 24
TYMP → 1,4-alpha-oligoglucan phosphorylase activity, angiogenesis, cell differentiation, chemotaxis, cytosol, glycosyltransferase activity, growth factor activity, metabolism, mitochondrial genome maintenance, multicellular organism development, pentosyltransferase activity, protein homodimerization activity, pyrimidine nucleobase metabolic process, pyrimidine nucleoside catabolic process, pyrimidine nucleoside metabolic process, pyrimidine nucleoside salvage, pyrimidine-nucleoside phosphorylase activity, regulation of gastric motility, regulation of myelination, regulation of signaling receptor activity
Bgee · 20
TYMP → apex of heart, blood, colon, duodenum, granulocyte, jejunum, liver, lung, monocyte, olfactory zone of nasal mucosa, proximal tubule, right lobe of liver, right lung, right uterine tube, spermatid, spermatocyte, spleen, testicle, upper lobe of left lung, vagina
RNA expression pattern · 20
TYMP → apex of heart, blood, colon, duodenum, granulocyte, jejunum, liver, lung, monocyte, olfactory zone of nasal mucosa, proximal tubule, right lobe of liver, right lung, right uterine tube, spermatid, spermatocyte, spleen, testicle, upper lobe of left lung, vagina
related to Function · 4
TYMP → Because, ECGF1, MNGIE, Thymidine
Band · 2
TYMP → 15 E3|15 44.86 cM, 22q13.33
Chr. · 2
TYMP → Chromosome 15 (mouse), Chromosome 22 (human)
End · 2
TYMP → 50,530,032 bp, 89,261,242 bp
2.4.2.4 · 1
TYMP → ↗
Aliases · 1
TYMP → TYMP, thymidine phosphorylase, ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF
Available structures · 1
TYMP → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1UOU, 2J0F, 2WK5, 2WK6

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Important terminology

thymidine phosphorylase gene bp chr human band chromosome 22 mngie cell growth endothelial mitochondrial enzyme ecgf1 factor location angiogenesis activity

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
TYMP2.4.2.41.00infobox
TYMPAliasesTYMP, thymidine phosphorylase, ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF1.00infobox
TYMPAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1UOU, 2J0F, 2WK5, 2WK61.00infobox
TYMPBand22q13.331.00infobox
TYMPBand15 E3|15 44.86 cM1.00infobox
TYMPBgeeright uterine tube1.00infobox
TYMPBgeegranulocyte1.00infobox
TYMPBgeemonocyte1.00infobox
TYMPBgeeright lung1.00infobox
TYMPBgeeupper lobe of left lung1.00infobox
TYMPBgeeolfactory zone of nasal mucosa1.00infobox
TYMPBgeespleen1.00infobox
TYMPBgeeapex of heart1.00infobox
TYMPBgeeblood1.00infobox
TYMPBgeeright lobe of liver1.00infobox
TYMPBgeeliver1.00infobox
TYMPBgeejejunum1.00infobox
TYMPBgeecolon1.00infobox
TYMPBgeeduodenum1.00infobox
TYMPBgeespermatocyte1.00infobox
TYMPBgeevagina1.00infobox
TYMPBgeespermatid1.00infobox
TYMPBgeetesticle1.00infobox
TYMPBgeeproximal tubule1.00infobox
TYMPBgeelung1.00infobox
TYMPBioGPSMore reference expression data1.00infobox
TYMPChr.Chromosome 22 (human)1.00infobox
TYMPChr.Chromosome 15 (mouse)1.00infobox
TYMPDatabasesNCBI: entry; OMA: entry1.00infobox
TYMPEnd50,530,032 bp1.00infobox

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