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Tuftsin is a tetrapeptide (Thr-Lys-Pro-Arg, TKPR) located in the Fc-domain of the heavy chain of immunoglobulin G (residues 289-292). It has an immunostimulatory effect. It is named for Tufts University where it was first discovered in 1983.
Standards, Function & Tuftsin analogues
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phagocytosis stimulation effect cells human cell cytotoxicity tetrapeptide residues enzyme blood active analogue leukemia first augmentation activity references membrane phagocytic
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Tuftsin | is a | tetrapeptide | 0.90 | text |
| Tuftsin | related to Augmentation of Tumor Necrosis Factor | Injection | 0.60 | section |
| Tuftsin | related to Augmentation of Tumor Necrosis Factor | TNF | 0.60 | section |
| Tuftsin | related to Augmentation of Tumor Necrosis Factor | This | 0.60 | section |
| Tuftsin | related to Augmentation of Tumor Necrosis Factor | HL60 | 0.60 | section |
| Tuftsin | related to Clinical significance | Poly | 0.60 | section |
| Tuftsin | related to Clinical significance | For | 0.60 | section |
| Tuftsin | related to Clinical significance | Plasmodium | 0.60 | section |
| Tuftsin | related to Clinical significance | B-bearing | 0.60 | section |
| Tuftsin | related to Clinical significance | Conjugates | 0.60 | section |
| Tuftsin | related to Effect of cell cytotoxicity | The | 0.60 | section |
| Tuftsin | related to Effect of cell cytotoxicity | T-cell-mediated | 0.60 | section |
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