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Tubulin beta-3 chain: Function, Overview & Role in cancer

Tubulin beta-3 chain, Class III β-tubulin, βIII-tubulin (β3-tubulin) or β-tubulin III, is a microtubule element of the tubulin family found almost exclusively in neurons, and in testis cells. In humans, it is encoded by the TUBB3 gene.

Language: English [EN]
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Tubulin beta-3 chain topic overview

The analysis highlights Function, Overview and Role in cancer as prominent areas in the source structure around Tubulin beta-3 chain.

Related topics
21
Source areas
3
Connected nodes
24
Extracted relationships
86
Related term clusters
10
Bridge connections
24

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 11 topics
Function · 9 topics
Role in cancer · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
TUBB3, CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4, tubulin beta 3 class III
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5IJ0, 5JCO, 5IJ9
Band
16q24.3 · 8|8 E1
Bgee
ganglionic eminence · superior frontal gyrus · hypothalamus · ventricular zone · primary visual cortex
BioGPS
n/a
Chr.
Chromosome 16 (human) · Chromosome 8 (mouse)

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Tubulin beta-3 chain

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Role in cancer

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Tubulin beta-3 chain connects Entity context

The extracted context around Tubulin beta-3 chain shows recurring relationship patterns in the source. For example, Tubulin beta-3 chain → axon, axon guidance, cell projection, cytoplasm, cytoskeleton, cytoskeleton organization, dendrite, dorsal root ganglion development, extracellular exosome, filopodium, growth cone, GTP binding, GTPase activity, lamellipodium, microtubule, microtubule cytoskeleton, microtubule cytoskeleton organization, microtubule-based process, mitotic cell cycle, netrin receptor binding Another extracted example is Tubulin beta-3 chain → anterior cingulate cortex, Brodmann area 9, CA3 field, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, entorhinal cortex, facial motor nucleus, ganglionic eminence, hypothalamus, medial ganglionic eminence, perirhinal cortex, prefrontal cortex, primary visual cortex, right frontal lobe, superior cervical ganglion, superior frontal gyrus, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

Tubulin beta-3 chain

Top relations

Gene ontology · 26
Tubulin beta-3 chain → axon, axon guidance, cell projection, cytoplasm, cytoskeleton, cytoskeleton organization, dendrite, dorsal root ganglion development, extracellular exosome, filopodium, growth cone, GTP binding, GTPase activity, lamellipodium, microtubule, microtubule cytoskeleton, microtubule cytoskeleton organization, microtubule-based process, mitotic cell cycle, netrin receptor binding
Bgee · 17
Tubulin beta-3 chain → anterior cingulate cortex, Brodmann area 9, CA3 field, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, entorhinal cortex, facial motor nucleus, ganglionic eminence, hypothalamus, medial ganglionic eminence, perirhinal cortex, prefrontal cortex, primary visual cortex, right frontal lobe, superior cervical ganglion, superior frontal gyrus, ventricular zone
RNA expression pattern · 17
Tubulin beta-3 chain → anterior cingulate cortex, Brodmann area 9, CA3 field, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, entorhinal cortex, facial motor nucleus, ganglionic eminence, hypothalamus, medial ganglionic eminence, perirhinal cortex, prefrontal cortex, primary visual cortex, right frontal lobe, superior cervical ganglion, superior frontal gyrus, ventricular zone
Band · 2
Tubulin beta-3 chain → 16q24.3, 8|8 E1
Chr. · 2
Tubulin beta-3 chain → Chromosome 16 (human), Chromosome 8 (mouse)
End · 2
Tubulin beta-3 chain → 124,148,754 bp, 89,938,761 bp
Aliases · 1
Tubulin beta-3 chain → TUBB3, CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4, tubulin beta 3 class III
Available structures · 1
Tubulin beta-3 chain → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5IJ0, 5JCO, 5IJ9
BioGPS · 1
Tubulin beta-3 chain → n/a
Databases · 1
Tubulin beta-3 chain → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

class iii β-tubulin tubb3 microtubule human gene bp cells expression cell chr band β3-tubulin chromosome neural neurons tubulin drugs βiii-tubulin

Tubulin beta-3 chain relationships Subject–Predicate–Object triples

TTTA extracted 86 structured relationships around Tubulin beta-3 chain. Examples in this analysis include Tubulin beta-3 chain → Aliases → TUBB3, CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4, tubulin beta 3 class III and Tubulin beta-3 chain → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5IJ0, 5JCO, 5IJ9. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Tubulin beta-3 chainAliasesTUBB3, CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4, tubulin beta 3 class III1.00infobox
Tubulin beta-3 chainAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5IJ0, 5JCO, 5IJ91.00infobox
Tubulin beta-3 chainBand16q24.31.00infobox
Tubulin beta-3 chainBand8|8 E11.00infobox
Tubulin beta-3 chainBgeeganglionic eminence1.00infobox
Tubulin beta-3 chainBgeesuperior frontal gyrus1.00infobox
Tubulin beta-3 chainBgeehypothalamus1.00infobox
Tubulin beta-3 chainBgeeventricular zone1.00infobox
Tubulin beta-3 chainBgeeprimary visual cortex1.00infobox
Tubulin beta-3 chainBgeeprefrontal cortex1.00infobox
Tubulin beta-3 chainBgeeright frontal lobe1.00infobox
Tubulin beta-3 chainBgeedorsolateral prefrontal cortex1.00infobox
Tubulin beta-3 chainBgeeBrodmann area 91.00infobox
Tubulin beta-3 chainBgeeanterior cingulate cortex1.00infobox
Tubulin beta-3 chainBgeesuperior cervical ganglion1.00infobox
Tubulin beta-3 chainBgeeperirhinal cortex1.00infobox
Tubulin beta-3 chainBgeemedial ganglionic eminence1.00infobox
Tubulin beta-3 chainBgeeentorhinal cortex1.00infobox
Tubulin beta-3 chainBgeefacial motor nucleus1.00infobox
Tubulin beta-3 chainBgeeCA3 field1.00infobox
Tubulin beta-3 chainBgeedentate gyrus of hippocampal formation granule cell1.00infobox
Tubulin beta-3 chainBioGPSn/a1.00infobox
Tubulin beta-3 chainChr.Chromosome 16 (human)1.00infobox
Tubulin beta-3 chainChr.Chromosome 8 (mouse)1.00infobox
Tubulin beta-3 chainDatabasesNCBI: entry; OMA: entry1.00infobox
Tubulin beta-3 chainEnd89,938,761 bp1.00infobox
Tubulin beta-3 chainEnd124,148,754 bp1.00infobox
Tubulin beta-3 chainEnsemblENSG000002589471.00infobox
Tubulin beta-3 chainEntrez103811.00infobox
Tubulin beta-3 chainExternal IDsOMIM: 602661; MGI: 107813; GeneCards: TUBB31.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Tubulin beta-3 chain bring nearby vocabulary together. In this analysis, examples include Tubulin, Neurons and Cells. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • microtubule
    • Drugs
    • Β3-tubulin
    • Dynamics
    • Also
    • Activity
    • Βiii-tubulin
    • Cell
    • Cells
    • Expression
    • Β-tubulin
    • Testis
    • Development
  • β-tubulin
    • Biomarker
    • Including
    • Mir-200c
    • Βiii-tubulin
    • Development
    • Expressed
    • Poor
    • Protein
    • Role
    • Tissues
    • Ability
    • Activity
  • role in cancer
    • Cells
    • Location
    • Tubulin
    • Tubb3
    • Dynamics
    • Role
    • Tissues
    • Ability
    • Chromosome
    • Gene
    • Βiii-tubulin
    • Also
  • Tubulin beta-3 chain
    • Tubulin
    • Neurons
    • Cells
    • Testis
    • Location
    • Role
    • Cancer
    • Chromosome
    • Gene
    • Bp
    • Chr
    • Human
  • tubulin beta-3 chain
    • Neurons
    • Tubulin
    • Cells
    • Testis
    • Location
    • Role
    • Cancer
    • Chromosome
    • Gene
    • Βiii-tubulin
    • Bp
    • Chr
  • gene
    • Location
    • Chromosome
    • Bp
    • Chr
    • Human
    • Band
    • Tubb3
    • Development
    • Expressed
    • Protein
    • Role
    • Tubulin
  • tubulin
    • Neurons
    • Cells
    • Testis
    • Location
    • Role
    • Cancer
    • Chromosome
    • Gene
    • Bp
    • Chr
    • Human
    • Βiii-tubulin
  • glial cells
    • Neurons
    • Tubulin
    • Cancer
    • Β3-tubulin
    • Expression
    • Microtubule
    • Β-tubulin
    • Iii
    • Testis
    • Class
    • Tissues
    • Ability

Connections between topic areas Semantic bridges

For Tubulin beta-3 chain, one of the stronger structural bridges in this analysis connects Tubulin beta-3 chain with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Tubulin beta-3 chain — Overview · splits 13 ⟂ 12
Tubulin beta-3 chain — Function · splits 15 ⟂ 10

Map overview Semantic statistics

Tubulin beta-3 chain

Nodes25
Edges24
Triples86
Avg. degree1.92
Density0.08
Components1

Source & methodology

TTTA analyzes the structure around Tubulin beta-3 chain to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Overview & Role in cancer, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Tubulin beta-3 chain · EN edition · Analysis: TopicsToTalkAbout

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