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Trypsin-1, also known as cationic trypsinogen, is a protein that in humans is encoded by the PRSS1 gene. Trypsin-1 is the main isoform of trypsinogen secreted by pancreas, the others are trypsin-2 (anionic trypsinogen), and trypsin-3 (meso-trypsinogen).
The analysis highlights Standards, Function and Overview as prominent areas in the source structure around Trypsin 1.
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Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
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The extracted context around Trypsin 1 shows recurring relationship patterns in the source. For example, Trypsin 1 → body of pancreas, body of stomach, colon, duodenum, ectocervix, esophagus, fundus, granulocyte, islet of Langerhans, jejunum, left uterine tube, liver, pancreas, quadriceps femoris muscle, right coronary artery, right lobe of liver, stomach, testicle Another extracted example is Trypsin 1 → blood microparticle, cobalamin metabolic process, collagen-containing extracellular matrix, digestion, extracellular exosome, extracellular matrix disassembly, extracellular region, extracellular space, hydrolase activity, metal ion binding, peptidase activity, proteolysis, serine-type endopeptidase activity, serine-type peptidase activity. Use these groups to spot repeated connection types before inspecting the individual relationships.
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gene bp human chr band chromosome trypsin trypsinogen pancreatitis prss1 pancreas trypsin-1 location protein also mouse function external pdb uniprot
TTTA extracted 75 structured relationships around Trypsin 1. Examples in this analysis include Trypsin 1 → 3.4.21.4 → ↗ and Trypsin 1 → Aliases → PRSS1, TRP1, TRY1, TRY4, TRYP1, Trypsin 1, protease, serine 1, serine protease 1. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Trypsin 1 | 3.4.21.4 | ↗ | 1.00 | infobox |
| Trypsin 1 | Aliases | PRSS1, TRP1, TRY1, TRY4, TRYP1, Trypsin 1, protease, serine 1, serine protease 1 | 1.00 | infobox |
| Trypsin 1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FXY, 1TRN, 2RA3, 4WWY, 4WXV | 1.00 | infobox |
| Trypsin 1 | Band | 7q34 | 1.00 | infobox |
| Trypsin 1 | Band | 6|6 B1 | 1.00 | infobox |
| Trypsin 1 | Bgee | body of pancreas | 1.00 | infobox |
| Trypsin 1 | Bgee | islet of Langerhans | 1.00 | infobox |
| Trypsin 1 | Bgee | duodenum | 1.00 | infobox |
| Trypsin 1 | Bgee | body of stomach | 1.00 | infobox |
| Trypsin 1 | Bgee | fundus | 1.00 | infobox |
| Trypsin 1 | Bgee | ectocervix | 1.00 | infobox |
| Trypsin 1 | Bgee | right coronary artery | 1.00 | infobox |
| Trypsin 1 | Bgee | testicle | 1.00 | infobox |
| Trypsin 1 | Bgee | left uterine tube | 1.00 | infobox |
| Trypsin 1 | Bgee | right lobe of liver | 1.00 | infobox |
| Trypsin 1 | Bgee | pancreas | 1.00 | infobox |
| Trypsin 1 | Bgee | stomach | 1.00 | infobox |
| Trypsin 1 | Bgee | granulocyte | 1.00 | infobox |
| Trypsin 1 | Bgee | colon | 1.00 | infobox |
| Trypsin 1 | Bgee | esophagus | 1.00 | infobox |
| Trypsin 1 | Bgee | jejunum | 1.00 | infobox |
| Trypsin 1 | Bgee | quadriceps femoris muscle | 1.00 | infobox |
| Trypsin 1 | Bgee | liver | 1.00 | infobox |
| Trypsin 1 | BioGPS | More reference expression data | 1.00 | infobox |
| Trypsin 1 | Chr. | Chromosome 7 (human) | 1.00 | infobox |
| Trypsin 1 | Chr. | Chromosome 6 (mouse) | 1.00 | infobox |
| Trypsin 1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Trypsin 1 | End | 142,753,076 bp | 1.00 | infobox |
| Trypsin 1 | End | 41,334,848 bp | 1.00 | infobox |
| Trypsin 1 | Ensembl | ENSG00000274247 ENSG00000204983 | 1.00 | infobox |
The concept neighborhoods around Trypsin 1 bring nearby vocabulary together. In this analysis, examples include Uniprot, Site and Cleaved. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Trypsin 1, one of the stronger structural bridges in this analysis connects Trypsin 1 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Trypsin 1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Trypsin 1 · EN edition · Analysis: TopicsToTalkAbout
