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Trypsin 1

Trypsin-1, also known as cationic trypsinogen, is a protein that in humans is encoded by the PRSS1 gene. Trypsin-1 is the main isoform of trypsinogen secreted by pancreas, the others are trypsin-2 (anionic trypsinogen), and trypsin-3 (meso-trypsinogen).

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3.4.21.4
Aliases
PRSS1, TRP1, TRY1, TRY4, TRYP1, Trypsin 1, protease, serine 1, serine protease 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FXY, 1TRN, 2RA3, 4WWY, 4WXV
Band
7q34 · 6|6 B1
Bgee
body of pancreas · islet of Langerhans · duodenum · body of stomach · fundus
BioGPS
More reference expression data

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Trypsin 1

Nodes15
Edges14
Triples75
Avg. degree1.87
Density0.133333
Components1

How this topic connects Entity context

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Trypsin 1

Top relations

Bgee · 18
Trypsin 1 → body of pancreas, body of stomach, colon, duodenum, ectocervix, esophagus, fundus, granulocyte, islet of Langerhans, jejunum, left uterine tube, liver, pancreas, quadriceps femoris muscle, right coronary artery, right lobe of liver, stomach, testicle
RNA expression pattern · 18
Trypsin 1 → body of pancreas, body of stomach, colon, duodenum, ectocervix, esophagus, fundus, granulocyte, islet of Langerhans, jejunum, left uterine tube, liver, pancreas, quadriceps femoris muscle, right coronary artery, right lobe of liver, stomach, testicle
Gene ontology · 14
Trypsin 1 → blood microparticle, cobalamin metabolic process, collagen-containing extracellular matrix, digestion, extracellular exosome, extracellular matrix disassembly, extracellular region, extracellular space, hydrolase activity, metal ion binding, peptidase activity, proteolysis, serine-type endopeptidase activity, serine-type peptidase activity
Band · 2
Trypsin 1 → 6|6 B1, 7q34
Chr. · 2
Trypsin 1 → Chromosome 6 (mouse), Chromosome 7 (human)
End · 2
Trypsin 1 → 142,753,076 bp, 41,334,848 bp
3.4.21.4 · 1
Trypsin 1 → ↗
Aliases · 1
Trypsin 1 → PRSS1, TRP1, TRY1, TRY4, TRYP1, Trypsin 1, protease, serine 1, serine protease 1
Available structures · 1
Trypsin 1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FXY, 1TRN, 2RA3, 4WWY, 4WXV
BioGPS · 1
Trypsin 1 → More reference expression data

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Important terminology

gene bp human chr band chromosome trypsin trypsinogen pancreatitis prss1 pancreas trypsin-1 location protein also mouse function external pdb uniprot

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Trypsin 13.4.21.41.00infobox
Trypsin 1AliasesPRSS1, TRP1, TRY1, TRY4, TRYP1, Trypsin 1, protease, serine 1, serine protease 11.00infobox
Trypsin 1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1FXY, 1TRN, 2RA3, 4WWY, 4WXV1.00infobox
Trypsin 1Band7q341.00infobox
Trypsin 1Band6|6 B11.00infobox
Trypsin 1Bgeebody of pancreas1.00infobox
Trypsin 1Bgeeislet of Langerhans1.00infobox
Trypsin 1Bgeeduodenum1.00infobox
Trypsin 1Bgeebody of stomach1.00infobox
Trypsin 1Bgeefundus1.00infobox
Trypsin 1Bgeeectocervix1.00infobox
Trypsin 1Bgeeright coronary artery1.00infobox
Trypsin 1Bgeetesticle1.00infobox
Trypsin 1Bgeeleft uterine tube1.00infobox
Trypsin 1Bgeeright lobe of liver1.00infobox
Trypsin 1Bgeepancreas1.00infobox
Trypsin 1Bgeestomach1.00infobox
Trypsin 1Bgeegranulocyte1.00infobox
Trypsin 1Bgeecolon1.00infobox
Trypsin 1Bgeeesophagus1.00infobox
Trypsin 1Bgeejejunum1.00infobox
Trypsin 1Bgeequadriceps femoris muscle1.00infobox
Trypsin 1Bgeeliver1.00infobox
Trypsin 1BioGPSMore reference expression data1.00infobox
Trypsin 1Chr.Chromosome 7 (human)1.00infobox
Trypsin 1Chr.Chromosome 6 (mouse)1.00infobox
Trypsin 1DatabasesNCBI: entry; OMA: entry1.00infobox
Trypsin 1End142,753,076 bp1.00infobox
Trypsin 1End41,334,848 bp1.00infobox
Trypsin 1EnsemblENSG00000274247 ENSG000002049831.00infobox

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