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Treprostinil, sold under the brand names Remodulin for infusion, Orenitram for oral, and Tyvaso for inhalation among others, is a vasodilator that is used for the treatment of pulmonary arterial hypertension.
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Explore the main themes, entities and connections around Treprostinil. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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inhalation medical use pulmonary hypertension approved united states treatment may medlineplus remodulin tyvaso arterial orenitram powder oral indicated vasodilator drug
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Treprostinil | AHFS/Drugs.com | Monograph | 1.00 | infobox |
| Treprostinil | ATC code | B01AC21 (WHO) | 1.00 | infobox |
| Treprostinil | Bioavailability | ~100% | 1.00 | infobox |
| Treprostinil | CAS Number | 81846-19-7 N | 1.00 | infobox |
| Treprostinil | ChEBI | CHEBI:50861 Y | 1.00 | infobox |
| Treprostinil | ChEMBL | ChEMBL1201254 N | 1.00 | infobox |
| Treprostinil | ChemSpider | 5293353 Y | 1.00 | infobox |
| Treprostinil | CompTox Dashboard (EPA) | DTXSID901021654 | 1.00 | infobox |
| Treprostinil | DrugBank | DB00374 Y | 1.00 | infobox |
| Treprostinil | ECHA InfoCard | 100.236.149 | 1.00 | infobox |
| Treprostinil | Elimination half-life | 4 hours | 1.00 | infobox |
| Treprostinil | Excretion | Urine (79% of administered dose is excreted as 4% unchanged drug and 64% as identified metabolites); feces (13%) | 1.00 | infobox |
| Treprostinil | Formula | C23H34O5 | 1.00 | infobox |
| Treprostinil | IUPHAR/BPS | 5820 | 1.00 | infobox |
| Treprostinil | KEGG | D06213 N | 1.00 | infobox |
| Treprostinil | KEGG | D08628 N | 1.00 | infobox |
| Treprostinil | Legal status | US: ℞-only | 1.00 | infobox |
| Treprostinil | Legal status | EU: Rx-only | 1.00 | infobox |
| Treprostinil | Legal status | In general: ℞ (Prescription only) | 1.00 | infobox |
| Treprostinil | License data | US DailyMed: Treprostinil | 1.00 | infobox |
| Treprostinil | MedlinePlus | a622038 | 1.00 | infobox |
| Treprostinil | Metabolism | Substantially metabolized by the liver | 1.00 | infobox |
| Treprostinil | Molar mass | 390.520 g·mol−1 | 1.00 | infobox |
| Treprostinil | Pregnancy category | AU: B3 | 1.00 | infobox |
| Treprostinil | PubChem CID | 6918140 | 1.00 | infobox |
| Treprostinil | Routes of administration | Subcutaneous, intravenous, inhalation, by mouth | 1.00 | infobox |
| Treprostinil | Trade names | Remodulin, Orenitram, Tyvaso, others | 1.00 | infobox |
| Treprostinil | UNII | RUM6K67ESG | 1.00 | infobox |
| Treprostinil | is a | vasodilator | 0.90 | text |
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