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Guselkumab

Guselkumab (/ɡjuˈsɛlkjumæb/ gew-SEL-kew-mab; sold under the brand name Tremfya) is a human monoclonal antibody against interleukin-23 used for the treatment of plaque psoriasis, psoriatic arthritis, ulcerative colitis, and Crohn's disease.

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Key facts & relationships

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AHFS/Drugs.com
Monograph
ATC code
L04AC16 (WHO)
CAS Number
1350289-85-8
ChemSpider
none
DrugBank
DB11834
Formula
C6402H9864N1676O1994S42

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Medical uses

Adverse effects

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Research

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Map overview Semantic statistics

Guselkumab

Nodes26
Edges25
Triples55
Avg. degree1.92
Density0.076923
Components1

How this topic connects Entity context

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Guselkumab

Top relations

related to Research · 12
Guselkumab → At, ClinicalTrials, Humira, IDs, III, NCT02207231, NCT02207244, PASI, Preliminary, Stelara, The, VOYAGE
related to history · 8
Guselkumab → Biologics License Application, BLA, Drug Administration, FDA, In November, Janssen, Janssen Pharmaceuticals, US Food
related to Legal status · 7
Guselkumab → Drug Administration, FDA, Health Canada, In July, In November, In September, US Food
Legal status · 5
Guselkumab → AU: S4 (Prescription only), CA: Rx-only, Schedule D, EU: Rx-only, UK: POM (Prescription only), US: ℞-only
related to Names · 2
Guselkumab → CNTO-1959, During
AHFS/Drugs.com · 1
Guselkumab → Monograph
ATC code · 1
Guselkumab → L04AC16 (WHO)
CAS Number · 1
Guselkumab → 1350289-85-8
ChemSpider · 1
Guselkumab → none
DrugBank · 1
Guselkumab → DB11834

Important terminology Word statistics

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Important terminology

treatment approved psoriatic arthritis plaque psoriasis ulcerative colitis tremfya us gew-sel-kew-mab fda patients crohn's disease adalimumab ustekinumab human administration ɡjuˈsɛlkjumæb

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
GuselkumabAHFS/Drugs.comMonograph1.00infobox
GuselkumabATC codeL04AC16 (WHO)1.00infobox
GuselkumabCAS Number1350289-85-81.00infobox
GuselkumabChemSpidernone1.00infobox
GuselkumabDrugBankDB118341.00infobox
GuselkumabFormulaC6402H9864N1676O1994S421.00infobox
GuselkumabKEGGD104381.00infobox
GuselkumabLegal statusAU: S4 (Prescription only)1.00infobox
GuselkumabLegal statusCA: Rx-only, Schedule D1.00infobox
GuselkumabLegal statusUK: POM (Prescription only)1.00infobox
GuselkumabLegal statusUS: ℞-only1.00infobox
GuselkumabLegal statusEU: Rx-only1.00infobox
GuselkumabLicense dataUS DailyMed: Guselkumab1.00infobox
GuselkumabMedlinePlusa6170361.00infobox
GuselkumabMolar mass143561.59 g·mol−11.00infobox
GuselkumabPregnancy categoryAU: B11.00infobox
GuselkumabPronunciation/ɡjuˈsɛlkjumæb/ gew-SEL-kew-mab1.00infobox
GuselkumabRoutes of administrationSubcutaneous, intravenous1.00infobox
GuselkumabSourceHuman1.00infobox
GuselkumabTargetIL231.00infobox
GuselkumabTrade namesTremfya1.00infobox
GuselkumabTypeWhole antibody1.00infobox
GuselkumabUNII089658A12D1.00infobox

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