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The tert-butyloxycarbonyl protecting group or tert-butoxycarbonyl protecting group (BOC group) is an acid-labile protecting group used in organic synthesis.
Overview & Amine protection
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group boc amine used amines di-tert-butyl dicarbonate acid protecting using methanol mixture ambient temperature synthesis aqueous sodium presence also accomplished
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| sodium hydroxide | instance of | is an acid-labile protecting group used in organic synthesis.The BOC group can be added to amines under aqueous conditions using di-tert-butyl dicarbonate in the presence of a base | 0.80 | text |
| anisole or thioanisole may be used | instance of | scavengers | 0.80 | text |
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