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Synpolydactyly

Synpolydactyly (SPD) is a joint presentation of syndactyly (fusion of digits) and polydactyly (production of supernumerary digits). SPD affects both hands and feet, often occurring symmetrically on both body sides. This is often a result of a mutation in the HOXD13 gene, as HOXD genes are necessary in early limb bud development and specification of the…

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Synpolydactyly

Nodes10
Edges9
Triples15
Avg. degree1.8
Density0.2
Components1

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Synpolydactyly

Top relations

related to Symptoms · 6
Synpolydactyly → However, HOXD13, II, In, SPD1, The
related to Management · 5
Synpolydactyly → Mild, Moderate, Post-surgical, Severe, Treatment

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Important terminology

hoxd13 gene symptoms cases often may digits spd affected also allele spd1 polyalanine found severe genetic individuals finger bones feet

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
significantly shortened handinstance ofas well as more severe symptoms0.80text
toe bonesinstance ofas well as more severe symptoms0.80text
and the big toe can be noticeably longinstance ofas well as more severe symptoms0.80text
angled inwardinstance ofas well as more severe symptoms0.80text
Synpolydactylyrelated to ManagementTreatment0.60section
Synpolydactylyrelated to ManagementMild0.60section
Synpolydactylyrelated to ManagementModerate0.60section
Synpolydactylyrelated to ManagementSevere0.60section
Synpolydactylyrelated to ManagementPost-surgical0.60section
Synpolydactylyrelated to SymptomsSPD10.60section
Synpolydactylyrelated to SymptomsII0.60section
Synpolydactylyrelated to SymptomsHOXD130.60section

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