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Subfunctionalization

Subfunctionalization was proposed by Stoltzfus (1999) and Force et al. (1999) as one of the possible outcomes of functional divergence that occurs after a gene duplication event, in which pairs of genes that originate from duplication, or paralogs, take on separate functions. Subfunctionalization is a neutral mutation process of constructive neutral…

Products, Alternative hypothesis & Gene sharing

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Alternative hypothesis

NeofunctionalizationNeutral mutationParsimonious
3 related topics

Gene sharing

Signal transductionTranscriptional regulationEnzyme
3 related topics

Hemoglobin

HemoglobinHuman genomeFetal hemoglobin
3 related topics

Segregation avoidance

Unequal crossing overPesticide
2 related topics

Topics to explore

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Overview

Alternative hypothesis

Specialization

Gene sharing

Duplication-Degeneration-Complementation

Segregation avoidance

Hemoglobin

Advanced semantic analysis

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Map overview Semantic statistics

Subfunctionalization

Nodes26
Edges25
Triples34
Avg. degree1.92
Density0.076923
Components1

How this topic connects Entity context

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Subfunctionalization

Top relations

related to Hemoglobin · 8
Subfunctionalization → Another, Conversely, Each, For, However, Human, In, This
related to Duplication-Degeneration-Complementation · 6
Subfunctionalization → DDC, Duplication- Degeneration- Complementation, In, One, The, This
related to Escape from adaptive conflict · 6
Subfunctionalization → Adaptive, As, It, The, There, This
related to Specialization · 6
Subfunctionalization → For, However, In, Isozymes, Specialization, When
related to Alternative hypothesis · 4
Subfunctionalization → Before, Neofunctionalization, Nevertheless, The
is a · 1
Subfunctionalization → neutral mutation process of constructive neutral evolution

Important terminology Word statistics

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Important terminology

gene function paralogs hemoglobin duplication ancestral one model example occurs sharing process functional genes original developmental possible neutral different perform

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Subfunctionalizationis aneutral mutation process of constructive neutral evolution0.90text
signal transductioninstance ofGene sharing is a fairly common occurrence and is most often seen in enzymes taking on a various subfunctions0.80text
transcriptional regulationinstance ofGene sharing is a fairly common occurrence and is most often seen in enzymes taking on a various subfunctions0.80text
the uterusinstance ofembryonic and fetal hemoglobin have higher oxygen affinity than adult hemoglobin giving them improved functionality in hypoxic environments0.80text
Subfunctionalizationrelated to Alternative hypothesisBefore0.60section
Subfunctionalizationrelated to Alternative hypothesisThe0.60section
Subfunctionalizationrelated to Alternative hypothesisNeofunctionalization0.60section
Subfunctionalizationrelated to Alternative hypothesisNevertheless0.60section
Subfunctionalizationrelated to Duplication-Degeneration-ComplementationIn0.60section
Subfunctionalizationrelated to Duplication-Degeneration-ComplementationDuplication- Degeneration- Complementation0.60section
Subfunctionalizationrelated to Duplication-Degeneration-ComplementationDDC0.60section
Subfunctionalizationrelated to Duplication-Degeneration-ComplementationThis0.60section

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    Min side: 3
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