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Steglich esterification

The Steglich esterification is a variation of an esterification with dicyclohexylcarbodiimide as a coupling reagent and 4-dimethylaminopyridine as a catalyst. The reaction was first described by Wolfgang Steglich in 1978. It is an adaptation of an older method for the formation of amides by means of DCC (dicyclohexylcarbodiimide) and…

Reaction mechanism & Overview

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Reaction mechanism

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Steglich esterification

Nodes18
Edges17
Triples3
Avg. degree1.89
Density0.111111
Components1

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Steglich esterification

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related to External links · 2
Steglich esterification → Mechanism, Steglich
is a · 1
Steglich esterification → variation of an esterification with dicyclohexylcarbodiimide as a coupling reagent and 4-dimethylaminopyridine as a catalyst

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Important terminology

reaction esterification steglich dicyclohexylcarbodiimide dcc mechanism amides 4-dimethylaminopyridine described organic catalyst 1-hydroxybenzotriazole urea dicyclohexylurea side-reaction variation coupling reagent first wolfgang

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SubjectPredicateObjectConfidenceSrc
Steglich esterificationis avariation of an esterification with dicyclohexylcarbodiimide as a coupling reagent and 4-dimethylaminopyridine as a catalyst0.90text
Steglich esterificationrelated to External linksMechanism0.60section
Steglich esterificationrelated to External linksSteglich0.60section

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