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SRT-2104

SRT-2104 is an experimental drug that was studied by Sirtris Pharmaceuticals as a small-molecule activator of the sirtuin subtype SIRT1. The compound progressed to Phase II human trials for Type II diabetes before development was discontinued, however it continues to be widely used in animal research into the functions of SIRT1.

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Key facts & relationships

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3D model (JSmol)
Interactive image
CAS Number
1093403-33-8
ChEMBL
ChEMBL4297436
ChemSpider
28637794
CompTox Dashboard (EPA)
DTXSID00648729
DrugBank
DB12186 Y

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Overview

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Map overview Semantic statistics

SRT-2104

Nodes8
Edges7
Triples11
Avg. degree1.75
Density0.25
Components1

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SRT-2104

Top relations

3D model (JSmol) · 1
SRT-2104 → Interactive image
CAS Number · 1
SRT-2104 → 1093403-33-8
ChEMBL · 1
SRT-2104 → ChEMBL4297436
ChemSpider · 1
SRT-2104 → 28637794
CompTox Dashboard (EPA) · 1
SRT-2104 → DTXSID00648729
DrugBank · 1
SRT-2104 → DB12186 Y
Formula · 1
SRT-2104 → C26H24N6O2S2
Molar mass · 1
SRT-2104 → 516.64 g·mol−1
PubChem CID · 1
SRT-2104 → 25108829
UNII · 1
SRT-2104 → 4521NR0J09

Important terminology Word statistics

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Important terminology

sirt1 small-molecule activator sirtuin experimental drug studied sirtris pharmaceuticals subtype compound progressed phase ii human trials type diabetes development discontinued

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SRT-21043D model (JSmol)Interactive image1.00infobox
SRT-2104CAS Number1093403-33-81.00infobox
SRT-2104ChEMBLChEMBL42974361.00infobox
SRT-2104ChemSpider286377941.00infobox
SRT-2104CompTox Dashboard (EPA)DTXSID006487291.00infobox
SRT-2104DrugBankDB12186 Y1.00infobox
SRT-2104FormulaC26H24N6O2S21.00infobox
SRT-2104Molar mass516.64 g·mol−11.00infobox
SRT-2104PubChem CID251088291.00infobox
SRT-2104UNII4521NR0J091.00infobox
SRT-2104is aexperimental drug that was studied by Sirtris Pharmaceuticals as a small-molecule activator of the sirtuin subtype SIRT10.90text

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