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Sphingosine kinase 2 is a protein that in humans is encoded by the SPHK2 gene.
The analysis highlights Overview and Inhibitors as prominent areas in the source structure around SPHK2.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around SPHK2 shows recurring relationship patterns in the source. For example, SPHK2 → ATP binding, blood vessel development, brain development, cell population proliferation, cellular response to phorbol 13-acetate 12-myristate, cytoplasm, cytosol, D-erythro-sphingosine kinase activity, endoplasmic reticulum, epigenetic maintenance of chromatin in transcription-competent conformation, female pregnancy, histone H2A-K5 acetylation, histone H2B-K12 acetylation, intracellular membrane-bounded organelle, kinase activity, lipid phosphorylation, lysosomal membrane, lysosome, membrane, metabolism Another extracted example is SPHK2 → anterior cingulate cortex, aortic valve, ascending aorta, Brodmann area 9, C1 segment, cingulate gyrus, crypt of lieberkuhn of small intestine, duodenum, epithelium of stomach, granulocyte, lip, mucosa of ileum, mucosa of transverse colon, otic placode, otic vesicle, prefrontal cortex, right frontal lobe, right hemisphere of cerebellum, right lobe of liver, saccule. Use these groups to spot repeated connection types before inspecting the individual relationships.
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sphingosine gene kinase bp chr human band protein proliferation chromosome 19 location phosphorylation encoded 1-phosphate also role cancer mouse cellular
TTTA extracted 114 structured relationships around SPHK2. Examples in this analysis include SPHK2 → 2.7.1.91 → ↗ and SPHK2 → Aliases → SPHK2, SK 2, SK-2, SPK 2, SPK-2, sphingosine kinase 2. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| SPHK2 | 2.7.1.91 | ↗ | 1.00 | infobox |
| SPHK2 | Aliases | SPHK2, SK 2, SK-2, SPK 2, SPK-2, sphingosine kinase 2 | 1.00 | infobox |
| SPHK2 | Band | 19q13.33 | 1.00 | infobox |
| SPHK2 | Band | 7|7 B3 | 1.00 | infobox |
| SPHK2 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| SPHK2 | Bgee | right frontal lobe | 1.00 | infobox |
| SPHK2 | Bgee | cingulate gyrus | 1.00 | infobox |
| SPHK2 | Bgee | anterior cingulate cortex | 1.00 | infobox |
| SPHK2 | Bgee | prefrontal cortex | 1.00 | infobox |
| SPHK2 | Bgee | C1 segment | 1.00 | infobox |
| SPHK2 | Bgee | right lobe of liver | 1.00 | infobox |
| SPHK2 | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| SPHK2 | Bgee | Brodmann area 9 | 1.00 | infobox |
| SPHK2 | Bgee | mucosa of ileum | 1.00 | infobox |
| SPHK2 | Bgee | saccule | 1.00 | infobox |
| SPHK2 | Bgee | otic placode | 1.00 | infobox |
| SPHK2 | Bgee | aortic valve | 1.00 | infobox |
| SPHK2 | Bgee | otic vesicle | 1.00 | infobox |
| SPHK2 | Bgee | granulocyte | 1.00 | infobox |
| SPHK2 | Bgee | lip | 1.00 | infobox |
| SPHK2 | Bgee | epithelium of stomach | 1.00 | infobox |
| SPHK2 | Bgee | duodenum | 1.00 | infobox |
| SPHK2 | Bgee | ascending aorta | 1.00 | infobox |
| SPHK2 | Bgee | crypt of lieberkuhn of small intestine | 1.00 | infobox |
| SPHK2 | BioGPS | n/a | 1.00 | infobox |
| SPHK2 | Chr. | Chromosome 19 (human) | 1.00 | infobox |
| SPHK2 | Chr. | Chromosome 7 (mouse) | 1.00 | infobox |
| SPHK2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| SPHK2 | End | 48,630,717 bp | 1.00 | infobox |
| SPHK2 | End | 45,367,426 bp | 1.00 | infobox |
The concept neighborhoods around SPHK2 bring nearby vocabulary together. In this analysis, examples include Kinase, Sphingosine and Activity. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For SPHK2, one of the stronger structural bridges in this analysis connects SPHK2 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around SPHK2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview & Inhibitors, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — SPHK2 · EN edition · Analysis: TopicsToTalkAbout
