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Sec61

Sec61, termed SecYEG in prokaryotes, is a membrane protein complex found in all domains of life. As the core component of the translocon, it transports proteins to the endoplasmic reticulum in eukaryotes and out of the cell in prokaryotes. It is a doughnut-shaped pore through the membrane with 3 different subunits (heterotrimeric), SecY (α), SecE (γ)…

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Key facts & relationships

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AlphaFold
IPR001901 · PF00584
Available protein structures:
IPR001901 · PF00584
InterPro
IPR001901
OPM protein
1rhz
PDB
IPR001901 PF00584 (ECOD; PDBsum)
Pfam
PF00584

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Overview

Structure

Species-specifics

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Map overview Semantic statistics

Sec61

Nodes25
Edges24
Triples44
Avg. degree1.92
Density0.08
Components1

How this topic connects Entity context

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Sec61

Top relations

related to Structure · 14
Sec61 → During, Hydrophobic, In, It, Its, Much, SecE, SecG, SecY, SecY/Sec61α, Secβ, The, They, X-ray
related to By taxon · 9
Sec61 → ATPase, BiP, EM, Eukaryotic, SecA, SecY, SecYEG, The, TM
related to Species-specifics · 6
Sec61 → Human, SEC61A1, SEC61A2SecG, SEC61BSecE, SEC61G, SecY
related to External links · 3
Sec61 → Medicine Medical Subject Headings, MeSH, National Library
AlphaFold · 2
Sec61 → IPR001901, PF00584
Available protein structures: · 2
Sec61 → IPR001901, PF00584
InterPro · 1
Sec61 → IPR001901
OPM protein · 1
Sec61 → 1rhz
PDB · 1
Sec61 → IPR001901 PF00584 (ECOD; PDBsum)
Pfam · 1
Sec61 → PF00584

Important terminology Word statistics

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Important terminology

secy protein membrane secg translocon sece archaeal eukaryotic called plug complex homologous proteins pore secyeg bacterial side hydrophobic translocation prokaryotes

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Sec61AlphaFoldIPR0019011.00infobox
Sec61AlphaFoldPF005841.00infobox
Sec61Available protein structures:IPR0019011.00infobox
Sec61Available protein structures:PF005841.00infobox
Sec61InterProIPR0019011.00infobox
Sec61OPM protein1rhz1.00infobox
Sec61PDBIPR001901 PF00584 (ECOD; PDBsum)1.00infobox
Sec61PfamPF005841.00infobox
Sec61PROSITEPS010671.00infobox
Sec61SCOP21rhz / SCOPe / SUPFAM1.00infobox
Sec61SymbolSecE1.00infobox
Sec61TCDB3.A.51.00infobox

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