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SECIS element

In biology, the SECIS element (SECIS: selenocysteine insertion sequence) is an RNA element around 60 nucleotides in length that adopts a stem-loop structure. This structural motif (pattern of nucleotides) directs the cell to translate UGA codons as selenocysteines (UGA is normally a stop codon). SECIS elements are thus a fundamental aspect of messenger…

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Characteristics

Secondary structureRNASBP260S ribosomal protein L30Wobble
6 related topics

Location and function

BacteriaArchaeaEukaryotes3' UTRMRNA
8 related topics

Overview

BiologyRNA elementNucleotidesStem-loopStructural motif
12 related topics

Detection in bioinformatics

RfamProtein-coding region
2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Domain
Eukaryota
GO
GO:0001514
PDB structures
PDBe
Rfam
RF00031
RNA type
Cis-reg
SO
SO:1001274

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Overview

Location and function

Characteristics

Detection in bioinformatics

Advanced semantic analysis

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Map overview Semantic statistics

SECIS element

Nodes33
Edges32
Triples61
Avg. degree1.94
Density0.060606
Components1

How this topic connects Entity context

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SECIS element

Top relations

related to From known SECIS elements · 17
SECIS element → Both SECISearch3, Covels, GenBank, Infernal, Infernal RNA, It, Methods, Rfam, RNA, RNAfold-based, SCEIS, SECIS, SECISearch, SECISearch3, The, The ERPIN, This
related to Eukaryotic SECIS · 12
SECIS element → A-G, AUGA, AUGA/GGGA, EEFSEC, Eukaryotic SECIS, GGGA, Group II, In, L30, SBP2, SECIS, The
related to Location and function · 9
SECIS element → EEFSEC, EF-Tu/eEF1, In, Methanococcus, One, SECIS, SelB, UGA, UTR
related to From known selenoproteins · 7
SECIS element → An, GGGA, Neospora, New, SECIS, Toxoplasma, UTR
related to Characteristics · 4
SECIS element → Although, RNA, SECIS, The SECIS
related to External links · 4
SECIS element → Page, Rfam, RfamPage, SECIS
Domain · 1
SECIS element → Eukaryota
GO · 1
SECIS element → GO:0001514
PDB structures · 1
SECIS element → PDBe
Rfam · 1
SECIS element → RF00031

Important terminology Word statistics

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Important terminology

secis elements element archaeal structure eukaryotic sequence selenoproteins rna selenocysteine nucleotides rfam bacterial eukaryotes found uga secondary version kink-turn auga

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SECIS elementDomainEukaryota1.00infobox
SECIS elementGOGO:00015141.00infobox
SECIS elementPDB structuresPDBe1.00infobox
SECIS elementRfamRF000311.00infobox
SECIS elementRNA typeCis-reg1.00infobox
SECIS elementSOSO:10012741.00infobox
SECIS elementSymbolSECIS_11.00infobox
SECIS elementrelated to CharacteristicsThe SECIS0.60section
SECIS elementrelated to CharacteristicsRNA0.60section
SECIS elementrelated to CharacteristicsAlthough0.60section
SECIS elementrelated to CharacteristicsSECIS0.60section
SECIS elementrelated to Eukaryotic SECISEukaryotic SECIS0.60section

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    Min side: 3
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