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Sec61: Measurement & Regions

Sec61, termed SecYEG in prokaryotes, is a membrane protein complex found in all domains of life. As the core component of the translocon, it transports proteins to the endoplasmic reticulum in eukaryotes and out of the cell in prokaryotes. It is a doughnut-shaped pore through the membrane with 3 different subunits (heterotrimeric), SecY (α), SecE (γ)…

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Sec61 topic overview

The analysis highlights Measurement and Regions as prominent areas in the source structure around Sec61.

Related topics
21
Source areas
3
Connected nodes
24
Extracted relationships
44
Concept neighborhoods
11
Bridge connections
24

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Structure · 9 topics
Overview · 6 topics
Species-specifics · 6 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR001901 · PF00584
Available protein structures:
IPR001901 · PF00584
InterPro
IPR001901
OPM protein
1rhz
PDB
IPR001901 PF00584 (ECOD; PDBsum)
Pfam
PF00584

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Species-specifics

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Sec61 connects Entity context

The extracted context around Sec61 shows recurring relationship patterns in the source. For example, Sec61 → During, Hydrophobic, In, It, Its, Much, SecE, SecG, SecY, SecY/Sec61α, Secβ, The, They, X-ray Another extracted example is Sec61 → ATPase, BiP, EM, Eukaryotic, SecA, SecY, SecYEG, The, TM. Use these groups to spot repeated connection types before inspecting the individual relationships.

Sec61

Top relations

related to Structure · 14
Sec61 → During, Hydrophobic, In, It, Its, Much, SecE, SecG, SecY, SecY/Sec61α, Secβ, The, They, X-ray
related to By taxon · 9
Sec61 → ATPase, BiP, EM, Eukaryotic, SecA, SecY, SecYEG, The, TM
related to Species-specifics · 6
Sec61 → Human, SEC61A1, SEC61A2SecG, SEC61BSecE, SEC61G, SecY
related to External links · 3
Sec61 → Medicine Medical Subject Headings, MeSH, National Library
AlphaFold · 2
Sec61 → IPR001901, PF00584
Available protein structures: · 2
Sec61 → IPR001901, PF00584
InterPro · 1
Sec61 → IPR001901
OPM protein · 1
Sec61 → 1rhz
PDB · 1
Sec61 → IPR001901 PF00584 (ECOD; PDBsum)
Pfam · 1
Sec61 → PF00584

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

secy protein membrane secg translocon sece archaeal eukaryotic called plug complex homologous proteins pore secyeg bacterial side hydrophobic translocation prokaryotes

Sec61 relationships Subject–Predicate–Object triples

TTTA extracted 44 structured relationships around Sec61. Examples in this analysis include Sec61 → AlphaFold → IPR001901 and Sec61 → AlphaFold → PF00584. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Sec61AlphaFoldIPR0019011.00infobox
Sec61AlphaFoldPF005841.00infobox
Sec61Available protein structures:IPR0019011.00infobox
Sec61Available protein structures:PF005841.00infobox
Sec61InterProIPR0019011.00infobox
Sec61OPM protein1rhz1.00infobox
Sec61PDBIPR001901 PF00584 (ECOD; PDBsum)1.00infobox
Sec61PfamPF005841.00infobox
Sec61PROSITEPS010671.00infobox
Sec61SCOP21rhz / SCOPe / SUPFAM1.00infobox
Sec61SymbolSecE1.00infobox
Sec61TCDB3.A.51.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Sec61 bring nearby vocabulary together. In this analysis, examples include Called, Protein and Complex. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Sec61
    • Called
    • Protein
    • Complex
    • Domains
    • Er
    • Found
    • Interacts
    • Life
    • Polypeptide
    • Prokaryotes
    • Region
    • Structure
  • sec61
    • Called
    • Protein
    • Complex
    • Domains
    • Er
    • Found
    • Interacts
    • Life
    • Polypeptide
    • Prokaryotes
    • Region
    • Structure
  • protein complex
    • Secyeg
    • Two-empire
    • Archaeal
    • Become
    • Domains
    • Found
    • Life
    • Prokaryotes
    • Sec61β
    • Structure
    • Three
    • Complex
  • plasma membrane
    • Protein
    • Hydrophobic
    • Pore
    • Sece
    • Become
    • Citation
    • Complex
    • Domains
    • Found
    • Life
    • Needed
    • Prokaryotes
  • homologous
    • Sec61β
    • Three
    • Sece
    • Secg
    • Eukaryotic
    • Two-empire
    • Secy
    • Archaeal
    • Become
    • Life
    • Needed
    • Structure
  • secy
    • Homologous
    • Two
    • Sec61β
    • Three
    • Bacterial
    • Eukaryotic
    • Two-empire
    • Archaeal
    • Become
    • Citation
    • Needed
    • Structure
  • archaeal
    • Two-empire
    • Become
    • Complex
    • Sec61β
    • Structure
    • Three
    • Bacterial
    • Eukaryotic
    • Homologous
    • Secyeg
    • Pore
    • Sece
  • two-empire
    • Archaeal
    • Become
    • Complex
    • Sec61β
    • Structure
    • Three
    • Bacterial
    • Eukaryotic
    • Homologous
    • Secyeg
    • Pore
    • Sece

Connections between topic areas Semantic bridges

For Sec61, one of the stronger structural bridges in this analysis connects Sec61 with Structure. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Sec61 — Structure · splits 15 ⟂ 10
Sec61 — Overview · splits 18 ⟂ 7
Sec61 — Species-specifics · splits 18 ⟂ 7

Map overview Semantic statistics

Sec61

Nodes25
Edges24
Triples44
Avg. degree1.92
Density0.08
Components1

Source & methodology

TTTA analyzes the structure around Sec61 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement & Regions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Sec61 · EN edition · Analysis: TopicsToTalkAbout

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