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SCN3B: Measurement, Function & Overview

Sodium channel subunit beta-3 is a protein that in humans is encoded by the SCN3B gene. Two alternatively spliced variants, encoding the same protein, have been identified.

Language: English [EN]
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SCN3B topic overview

The analysis highlights Measurement, Function and Overview as prominent areas in the source structure around SCN3B.

Related topics
4
Source areas
2
Connected nodes
6
Extracted relationships
95
Concept neighborhoods
6
Bridge connections
6

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SCN3B, ATFB16, BRGDA7, HSA243396, SCNB3, sodium voltage-gated channel beta subunit 3
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4L1D
Band
11q24.1 · 9|9 A5.1
Bgee
middle temporal gyrus · orbitofrontal cortex · Brodmann area 46 · entorhinal cortex · superior frontal gyrus
BioGPS
More reference expression data
Chr.
Chromosome 11 (human) · Chromosome 9 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How SCN3B connects Entity context

The extracted context around SCN3B shows recurring relationship patterns in the source. For example, SCN3B → atrial cardiac muscle cell action potential, cardiac conduction, cardiac muscle cell action potential involved in contraction, cardiac muscle contraction, integral component of membrane, ion transport, membrane, membrane depolarization, membrane depolarization during action potential, membrane depolarization during cardiac muscle cell action potential, nervous system development, plasma membrane, positive regulation of heart rate, positive regulation of sodium ion transport, protein localization to plasma membrane, regulation of atrial cardiac muscle cell membrane depolarization, regulation of heart rate by cardiac conduction, regulation of ion transmembrane transport, regulation of sodium ion transmembrane transporter activity, regulation of ventricular cardiac muscle cell membrane depolarization Another extracted example is SCN3B → Brodmann area 23, Brodmann area 46, dentate gyrus, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, entorhinal cortex, external carotid artery, hippocampus proper, middle temporal gyrus, nucleus accumbens, olfactory epithelium, orbitofrontal cortex, piriform cortex, postcentral gyrus, prefrontal cortex, Region I of hippocampus proper, superior cervical ganglion, superior frontal gyrus, ventral tegmental area. Use these groups to spot repeated connection types before inspecting the individual relationships.

SCN3B

Top relations

Gene ontology · 34
SCN3B → atrial cardiac muscle cell action potential, cardiac conduction, cardiac muscle cell action potential involved in contraction, cardiac muscle contraction, integral component of membrane, ion transport, membrane, membrane depolarization, membrane depolarization during action potential, membrane depolarization during cardiac muscle cell action potential, nervous system development, plasma membrane, positive regulation of heart rate, positive regulation of sodium ion transport, protein localization to plasma membrane, regulation of atrial cardiac muscle cell membrane depolarization, regulation of heart rate by cardiac conduction, regulation of ion transmembrane transport, regulation of sodium ion transmembrane transporter activity, regulation of ventricular cardiac muscle cell membrane depolarization
Bgee · 19
SCN3B → Brodmann area 23, Brodmann area 46, dentate gyrus, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, entorhinal cortex, external carotid artery, hippocampus proper, middle temporal gyrus, nucleus accumbens, olfactory epithelium, orbitofrontal cortex, piriform cortex, postcentral gyrus, prefrontal cortex, Region I of hippocampus proper, superior cervical ganglion, superior frontal gyrus, ventral tegmental area
RNA expression pattern · 19
SCN3B → Brodmann area 23, Brodmann area 46, dentate gyrus, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, entorhinal cortex, external carotid artery, hippocampus proper, middle temporal gyrus, nucleus accumbens, olfactory epithelium, orbitofrontal cortex, piriform cortex, postcentral gyrus, prefrontal cortex, Region I of hippocampus proper, superior cervical ganglion, superior frontal gyrus, ventral tegmental area
Band · 2
SCN3B → 11q24.1, 9|9 A5.1
Chr. · 2
SCN3B → Chromosome 11 (human), Chromosome 9 (mouse)
End · 2
SCN3B → 123,655,244 bp, 40,202,914 bp
Aliases · 1
SCN3B → SCN3B, ATFB16, BRGDA7, HSA243396, SCNB3, sodium voltage-gated channel beta subunit 3
Available structures · 1
SCN3B → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4L1D
BioGPS · 1
SCN3B → More reference expression data
Databases · 1
SCN3B → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene human sodium chr band protein channel chromosome 11 subunit external location voltage-gated mouse beta function search 655 244

SCN3B relationships Subject–Predicate–Object triples

TTTA extracted 95 structured relationships around SCN3B. Examples in this analysis include SCN3B → Aliases → SCN3B, ATFB16, BRGDA7, HSA243396, SCNB3, sodium voltage-gated channel beta subunit 3 and SCN3B → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4L1D. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
SCN3BAliasesSCN3B, ATFB16, BRGDA7, HSA243396, SCNB3, sodium voltage-gated channel beta subunit 31.00infobox
SCN3BAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4L1D1.00infobox
SCN3BBand11q24.11.00infobox
SCN3BBand9|9 A5.11.00infobox
SCN3BBgeemiddle temporal gyrus1.00infobox
SCN3BBgeeorbitofrontal cortex1.00infobox
SCN3BBgeeBrodmann area 461.00infobox
SCN3BBgeeentorhinal cortex1.00infobox
SCN3BBgeesuperior frontal gyrus1.00infobox
SCN3BBgeeRegion I of hippocampus proper1.00infobox
SCN3BBgeeprefrontal cortex1.00infobox
SCN3BBgeepostcentral gyrus1.00infobox
SCN3BBgeedorsolateral prefrontal cortex1.00infobox
SCN3BBgeeBrodmann area 231.00infobox
SCN3BBgeesuperior cervical ganglion1.00infobox
SCN3BBgeeolfactory epithelium1.00infobox
SCN3BBgeedentate gyrus1.00infobox
SCN3BBgeehippocampus proper1.00infobox
SCN3BBgeeexternal carotid artery1.00infobox
SCN3BBgeedentate gyrus of hippocampal formation granule cell1.00infobox
SCN3BBgeenucleus accumbens1.00infobox
SCN3BBgeepiriform cortex1.00infobox
SCN3BBgeeventral tegmental area1.00infobox
SCN3BBioGPSMore reference expression data1.00infobox
SCN3BChr.Chromosome 11 (human)1.00infobox
SCN3BChr.Chromosome 9 (mouse)1.00infobox
SCN3BDatabasesNCBI: entry; OMA: entry1.00infobox
SCN3BEnd123,655,244 bp1.00infobox
SCN3BEnd40,202,914 bp1.00infobox
SCN3BEnsemblENSG000001662571.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around SCN3B bring nearby vocabulary together. In this analysis, examples include Subunit, External and Function. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • SCN3B
    • Subunit
    • External
    • Function
    • Search
    • Voltage-gated
    • Sodium
    • Beta
    • Gene
    • Location
    • Chromosome
    • Bp
    • Chr
  • scn3b
    • Subunit
    • External
    • Function
    • Search
    • Voltage-gated
    • Sodium
    • Beta
    • Gene
    • Location
    • Chromosome
    • Bp
    • Chr
  • protein
    • Entry
    • Ncbi
    • Sodium
    • Scn3b
    • Subunit
    • Human
    • Alternatively
    • Encoded
    • Gene
    • Humans
    • Spliced
    • Transmembrane
  • gene
    • Subunit
    • Sodium
    • Beta
    • Location
    • Scn3b
    • Chromosome
    • Bp
    • Chr
    • Human
    • A5
    • Cardiac
    • End
  • action potentials
    • Muscle
    • Transmembrane
    • Cardiac
    • End
    • Entry
    • External
    • Function
    • Mouse
    • Ncbi
    • One
    • Search
    • Voltage-gated
  • function
    • Search
    • Voltage-gated
    • Beta
    • Location
    • Scn3b
    • Chromosome
    • Subunit
    • Transmembrane
    • Bp
    • Chr
    • Human
    • Sodium

Connections between topic areas Semantic bridges

For SCN3B, one of the stronger structural bridges in this analysis connects SCN3B with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
SCN3BOverview · splits 4 ⟂ 3
SCN3BFunction · splits 4 ⟂ 3

Map overview Semantic statistics

SCN3B

Nodes7
Edges6
Triples95
Avg. degree1.71
Density0.285714
Components1

Source & methodology

TTTA analyzes the structure around SCN3B to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — SCN3B · EN edition · Analysis: TopicsToTalkAbout

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