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SCN1B

Sodium channel subunit beta-1 is a protein that in humans is encoded by the SCN1B gene.

Measurement, Clinical significance & Overview

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Topic orientation

SCN1B at a glance

The strongest research directions include Clinical significance. Use the connected concepts below as starting points, not as a keyword checklist.

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Explore the main themes, entities and connections around SCN1B. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Clinical significance

3 related topics

Overview

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
SCN1B, ATFB13, BRGDA5, GEFSP1, sodium voltage-gated channel beta subunit 1, EIEE52, DEE52
Band
19q13.11 · 7 B1|7 19.3 cM
Bgee
primary visual cortex · right hemisphere of cerebellum · gastrocnemius muscle · right frontal lobe · muscle of thigh
BioGPS
More reference expression data
Chr.
Chromosome 19 (human) · Chromosome 7 (mouse)
Databases
NCBI: entry; OMA: entry

Topics to explore

A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How this topic connects Entity context

Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.

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SCN1B

Top relations

Gene ontology · 42
SCN1B → axon guidance, cardiac conduction, cardiac muscle cell action potential involved in contraction, cardiac muscle contraction, cell adhesion, chemical synaptic transmission, corticospinal neuron axon guidance, extracellular region, integral component of membrane, intercalated disc, ion transport, locomotion, membrane, membrane depolarization, membrane depolarization during cardiac muscle cell action potential, membrane depolarization during Purkinje myocyte cell action potential, neuronal action potential propagation, node of Ranvier, plasma membrane, positive regulation of neuron projection development
Bgee · 17
SCN1B → Brodmann area 9, CA3 field, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, extensor digitorum longus muscle, gastrocnemius muscle, muscle of thigh, perirhinal cortex, prefrontal cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, skeletal muscle tissue, superior frontal gyrus, temporal muscle, triceps brachii muscle
RNA expression pattern · 17
SCN1B → Brodmann area 9, CA3 field, cerebellar cortex, dentate gyrus of hippocampal formation granule cell, dorsolateral prefrontal cortex, extensor digitorum longus muscle, gastrocnemius muscle, muscle of thigh, perirhinal cortex, prefrontal cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, skeletal muscle tissue, superior frontal gyrus, temporal muscle, triceps brachii muscle
related to External links · 8
SCN1B → Brugada, GeneReviews/NIH/NCBI/UW, Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library
related to Clinical significance · 4
SCN1B → Brugada, Dravet Syndrome, GEFS, Mutation
Band · 2
SCN1B → 19q13.11, 7 B1|7 19.3 cM
Chr. · 2
SCN1B → Chromosome 19 (human), Chromosome 7 (mouse)
End · 2
SCN1B → 30,826,428 bp, 35,040,449 bp
Aliases · 1
SCN1B → SCN1B, ATFB13, BRGDA5, GEFSP1, sodium voltage-gated channel beta subunit 1, EIEE52, DEE52
BioGPS · 1
SCN1B → More reference expression data

Important terminology Word statistics

Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp human sodium channel gene chr subunit band voltage-gated chromosome 19 protein location beta-1 alpha omim mouse propagation action muscle

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
SCN1BAliasesSCN1B, ATFB13, BRGDA5, GEFSP1, sodium voltage-gated channel beta subunit 1, EIEE52, DEE521.00infobox
SCN1BBand19q13.111.00infobox
SCN1BBand7 B1|7 19.3 cM1.00infobox
SCN1BBgeeprimary visual cortex1.00infobox
SCN1BBgeeright hemisphere of cerebellum1.00infobox
SCN1BBgeegastrocnemius muscle1.00infobox
SCN1BBgeeright frontal lobe1.00infobox
SCN1BBgeemuscle of thigh1.00infobox
SCN1BBgeeskeletal muscle tissue1.00infobox
SCN1BBgeedorsolateral prefrontal cortex1.00infobox
SCN1BBgeeBrodmann area 91.00infobox
SCN1BBgeesuperior frontal gyrus1.00infobox
SCN1BBgeeprefrontal cortex1.00infobox
SCN1BBgeedentate gyrus of hippocampal formation granule cell1.00infobox
SCN1BBgeecerebellar cortex1.00infobox
SCN1BBgeeextensor digitorum longus muscle1.00infobox
SCN1BBgeeCA3 field1.00infobox
SCN1BBgeeperirhinal cortex1.00infobox
SCN1BBgeetriceps brachii muscle1.00infobox
SCN1BBgeetemporal muscle1.00infobox
SCN1BBioGPSMore reference expression data1.00infobox
SCN1BChr.Chromosome 19 (human)1.00infobox
SCN1BChr.Chromosome 7 (mouse)1.00infobox
SCN1BDatabasesNCBI: entry; OMA: entry1.00infobox
SCN1BEnd35,040,449 bp1.00infobox
SCN1BEnd30,826,428 bp1.00infobox
SCN1BEnsemblENSG000001057111.00infobox
SCN1BEntrez63241.00infobox
SCN1BExternal IDsOMIM: 600235; MGI: 98247; GeneCards: SCN1B1.00infobox
SCN1BGene location (Human)Gene location (Human)Chr.Chromosome 19 (human)Band19q13.11Start35,030,470 bpEnd35,040,449 bp1.00infobox

Related concept clusters Concept neighborhoods

Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Map overview Semantic statistics

    Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.

    SCN1B

    Nodes8
    Edges7
    Triples111
    Avg. degree1.75
    Density0.25
    Components1
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