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Rootletin

Rootletin, also known as ciliary rootlet coiled-coil protein (CROCC) is a protein in humans that is encoded by the CROCC gene. Rootletin is a component of the ciliary rootlet and, together with CEP68 and CEP250, is required for centrosome cohesion.

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Aliases
CROCC, ROLT, ciliary rootlet coiled-coil, rootletin, TAX1BP2
Band
1p36.13 · 4|4 D3
Bgee
right uterine tube · sural nerve · right hemisphere of cerebellum · olfactory zone of nasal mucosa · granulocyte
BioGPS
n/a
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)
Databases
NCBI: entry; OMA: entry

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Rootletin

Nodes9
Edges8
Triples96
Avg. degree1.78
Density0.222222
Components1

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Rootletin

Top relations

Gene ontology · 29
Rootletin → actin binding, actin cytoskeleton, cell cycle, cell projection, cell projection organization, centriole, centriole-centriole cohesion, centrosome, centrosome cycle, ciliary basal body organization, ciliary rootlet, cilium, cytoplasm, cytoskeleton, cytosol, epithelial structure maintenance, establishment of organelle localization, extracellular exosome, kinesin binding, microtubule organizing center
Bgee · 20
Rootletin → apex of heart, body of uterus, canal of the cervix, epithelium of lens, granulocyte, left uterine tube, lens, neural layer of retina, olfactory tubercle, olfactory zone of nasal mucosa, otic vesicle, primary visual cortex, retinal pigment epithelium, right hemisphere of cerebellum, right ovary, right uterine tube, subiculum, superior frontal gyrus, sural nerve, ventricular zone
RNA expression pattern · 20
Rootletin → apex of heart, body of uterus, canal of the cervix, epithelium of lens, granulocyte, left uterine tube, lens, neural layer of retina, olfactory tubercle, olfactory zone of nasal mucosa, otic vesicle, primary visual cortex, retinal pigment epithelium, right hemisphere of cerebellum, right ovary, right uterine tube, subiculum, superior frontal gyrus, sural nerve, ventricular zone
related to Function · 3
Rootletin → Expression, It, This
related to Protein interactions · 3
Rootletin → C-Nap1, Furthermore, Nek2
Band · 2
Rootletin → 1p36.13, 4|4 D3
Chr. · 2
Rootletin → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
Rootletin → 140,787,861 bp, 16,972,964 bp
Aliases · 1
Rootletin → CROCC, ROLT, ciliary rootlet coiled-coil, rootletin, TAX1BP2
BioGPS · 1
Rootletin → n/a

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Important terminology

protein ciliary rootlet structure bp chr centrosome human band gene chromosome crocc coiled-coil cohesion location end mouse component mitosis function

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
RootletinAliasesCROCC, ROLT, ciliary rootlet coiled-coil, rootletin, TAX1BP21.00infobox
RootletinBand1p36.131.00infobox
RootletinBand4|4 D31.00infobox
RootletinBgeeright uterine tube1.00infobox
RootletinBgeesural nerve1.00infobox
RootletinBgeeright hemisphere of cerebellum1.00infobox
RootletinBgeeolfactory zone of nasal mucosa1.00infobox
RootletinBgeegranulocyte1.00infobox
RootletinBgeeapex of heart1.00infobox
RootletinBgeeright ovary1.00infobox
RootletinBgeecanal of the cervix1.00infobox
RootletinBgeeleft uterine tube1.00infobox
RootletinBgeebody of uterus1.00infobox
RootletinBgeeneural layer of retina1.00infobox
RootletinBgeesuperior frontal gyrus1.00infobox
RootletinBgeelens1.00infobox
RootletinBgeeolfactory tubercle1.00infobox
RootletinBgeeretinal pigment epithelium1.00infobox
RootletinBgeeventricular zone1.00infobox
RootletinBgeeotic vesicle1.00infobox
RootletinBgeeprimary visual cortex1.00infobox
RootletinBgeesubiculum1.00infobox
RootletinBgeeepithelium of lens1.00infobox
RootletinBioGPSn/a1.00infobox
RootletinChr.Chromosome 1 (human)1.00infobox
RootletinChr.Chromosome 4 (mouse)1.00infobox
RootletinDatabasesNCBI: entry; OMA: entry1.00infobox
RootletinEnd16,972,964 bp1.00infobox
RootletinEnd140,787,861 bp1.00infobox
RootletinEnsemblENSG000000584531.00infobox

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