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Ring finger protein 213 is a protein that in humans is encoded by the RNF213 gene. RNF213 is a 591kDa cytosolic E3 ubiquitin ligase with RING finger and AAA+ ATPase domains.
The analysis highlights Clinical relevance and Overview as prominent areas in the source structure around RNF213.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around RNF213 shows recurring relationship patterns in the source. For example, RNF213 → bone marrow cell, cervix, epithelium of small intestine, gastric mucosa, granulocyte, interventricular septum, lymph node, mesenteric lymph nodes, monocyte, otolith organ, ovary, pancreatic ductal cell, right lobe of thyroid gland, right uterine tube, spleen, stroma of bone marrow, submandibular gland, sural nerve, upper lobe of left lung, utricle Another extracted example is RNF213 → angiogenesis, ATPase activity, cytoplasm, cytosol, hydrolase activity, membrane, metal ion binding, negative regulation of non-canonical Wnt signaling pathway, nucleolus, protein autoubiquitination, protein binding, protein homooligomerization, protein polyubiquitination, protein ubiquitination, sprouting angiogenesis, transferase activity, ubiquitin-dependent protein catabolic process, ubiquitin-protein transferase activity. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp gene chr human band chromosome 17 ring finger protein location moyamoya disease mouse 17q25 213 atpase humans activity 398
TTTA extracted 89 structured relationships around RNF213. Examples in this analysis include RNF213 → 2.3.2.27 → ↗ and RNF213 → Aliases → RNF213, ALO17, C17orf27, KIAA1618, MYMY2, MYSTR, NET57, ring finger protein 213. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| RNF213 | 2.3.2.27 | ↗ | 1.00 | infobox |
| RNF213 | Aliases | RNF213, ALO17, C17orf27, KIAA1618, MYMY2, MYSTR, NET57, ring finger protein 213 | 1.00 | infobox |
| RNF213 | Band | 17q25.3 | 1.00 | infobox |
| RNF213 | Band | 11 E2|11 83.48 cM | 1.00 | infobox |
| RNF213 | Bgee | granulocyte | 1.00 | infobox |
| RNF213 | Bgee | pancreatic ductal cell | 1.00 | infobox |
| RNF213 | Bgee | spleen | 1.00 | infobox |
| RNF213 | Bgee | sural nerve | 1.00 | infobox |
| RNF213 | Bgee | bone marrow cell | 1.00 | infobox |
| RNF213 | Bgee | upper lobe of left lung | 1.00 | infobox |
| RNF213 | Bgee | monocyte | 1.00 | infobox |
| RNF213 | Bgee | right lobe of thyroid gland | 1.00 | infobox |
| RNF213 | Bgee | right uterine tube | 1.00 | infobox |
| RNF213 | Bgee | gastric mucosa | 1.00 | infobox |
| RNF213 | Bgee | cervix | 1.00 | infobox |
| RNF213 | Bgee | lymph node | 1.00 | infobox |
| RNF213 | Bgee | epithelium of small intestine | 1.00 | infobox |
| RNF213 | Bgee | stroma of bone marrow | 1.00 | infobox |
| RNF213 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| RNF213 | Bgee | ovary | 1.00 | infobox |
| RNF213 | Bgee | otolith organ | 1.00 | infobox |
| RNF213 | Bgee | utricle | 1.00 | infobox |
| RNF213 | Bgee | interventricular septum | 1.00 | infobox |
| RNF213 | Bgee | submandibular gland | 1.00 | infobox |
| RNF213 | BioGPS | n/a | 1.00 | infobox |
| RNF213 | Chr. | Chromosome 17 (human) | 1.00 | infobox |
| RNF213 | Chr. | Chromosome 11 (mouse) | 1.00 | infobox |
| RNF213 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| RNF213 | End | 80,398,794 bp | 1.00 | infobox |
| RNF213 | End | 119,378,244 bp | 1.00 | infobox |
The concept neighborhoods around RNF213 bring nearby vocabulary together. In this analysis, examples include Consumption, Oxygen and Sequencing. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For RNF213, one of the stronger structural bridges in this analysis connects RNF213 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around RNF213 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical relevance & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — RNF213 · EN edition · Analysis: TopicsToTalkAbout