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RNF213

Ring finger protein 213 is a protein that in humans is encoded by the RNF213 gene. RNF213 is a 591kDa cytosolic E3 ubiquitin ligase with RING finger and AAA+ ATPase domains.

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Clinical relevance

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2.3.2.27
Aliases
RNF213, ALO17, C17orf27, KIAA1618, MYMY2, MYSTR, NET57, ring finger protein 213
Band
17q25.3 · 11 E2|11 83.48 cM
Bgee
granulocyte · pancreatic ductal cell · spleen · sural nerve · bone marrow cell
BioGPS
n/a
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)

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Overview

Clinical relevance

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Map overview Semantic statistics

RNF213

Nodes9
Edges8
Triples89
Avg. degree1.78
Density0.222222
Components1

How this topic connects Entity context

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RNF213

Top relations

Bgee · 20
RNF213 → bone marrow cell, cervix, epithelium of small intestine, gastric mucosa, granulocyte, interventricular septum, lymph node, mesenteric lymph nodes, monocyte, otolith organ, ovary, pancreatic ductal cell, right lobe of thyroid gland, right uterine tube, spleen, stroma of bone marrow, submandibular gland, sural nerve, upper lobe of left lung, utricle
RNA expression pattern · 20
RNF213 → bone marrow cell, cervix, epithelium of small intestine, gastric mucosa, granulocyte, interventricular septum, lymph node, mesenteric lymph nodes, monocyte, otolith organ, ovary, pancreatic ductal cell, right lobe of thyroid gland, right uterine tube, spleen, stroma of bone marrow, submandibular gland, sural nerve, upper lobe of left lung, utricle
Gene ontology · 18
RNF213 → angiogenesis, ATPase activity, cytoplasm, cytosol, hydrolase activity, membrane, metal ion binding, negative regulation of non-canonical Wnt signaling pathway, nucleolus, protein autoubiquitination, protein binding, protein homooligomerization, protein polyubiquitination, protein ubiquitination, sprouting angiogenesis, transferase activity, ubiquitin-dependent protein catabolic process, ubiquitin-protein transferase activity
related to Clinical relevance · 8
RNF213 → Arg4810Lys, Chromosome-wide, Comparative, Direct, Genome-wide, Given, Japanese, Moyamoya
Band · 2
RNF213 → 11 E2|11 83.48 cM, 17q25.3
Chr. · 2
RNF213 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
RNF213 → 119,378,244 bp, 80,398,794 bp
2.3.2.27 · 1
RNF213 → ↗
Aliases · 1
RNF213 → RNF213, ALO17, C17orf27, KIAA1618, MYMY2, MYSTR, NET57, ring finger protein 213
BioGPS · 1
RNF213 → n/a

Important terminology Word statistics

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Important terminology

bp gene chr human band chromosome 17 ring finger protein location moyamoya disease mouse 17q25 213 atpase humans activity 398

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
RNF2132.3.2.271.00infobox
RNF213AliasesRNF213, ALO17, C17orf27, KIAA1618, MYMY2, MYSTR, NET57, ring finger protein 2131.00infobox
RNF213Band17q25.31.00infobox
RNF213Band11 E2|11 83.48 cM1.00infobox
RNF213Bgeegranulocyte1.00infobox
RNF213Bgeepancreatic ductal cell1.00infobox
RNF213Bgeespleen1.00infobox
RNF213Bgeesural nerve1.00infobox
RNF213Bgeebone marrow cell1.00infobox
RNF213Bgeeupper lobe of left lung1.00infobox
RNF213Bgeemonocyte1.00infobox
RNF213Bgeeright lobe of thyroid gland1.00infobox
RNF213Bgeeright uterine tube1.00infobox
RNF213Bgeegastric mucosa1.00infobox
RNF213Bgeecervix1.00infobox
RNF213Bgeelymph node1.00infobox
RNF213Bgeeepithelium of small intestine1.00infobox
RNF213Bgeestroma of bone marrow1.00infobox
RNF213Bgeemesenteric lymph nodes1.00infobox
RNF213Bgeeovary1.00infobox
RNF213Bgeeotolith organ1.00infobox
RNF213Bgeeutricle1.00infobox
RNF213Bgeeinterventricular septum1.00infobox
RNF213Bgeesubmandibular gland1.00infobox
RNF213BioGPSn/a1.00infobox
RNF213Chr.Chromosome 17 (human)1.00infobox
RNF213Chr.Chromosome 11 (mouse)1.00infobox
RNF213DatabasesNCBI: entry; OMA: entry1.00infobox
RNF213End80,398,794 bp1.00infobox
RNF213End119,378,244 bp1.00infobox

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