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RNF168: Overview, Related Topics & Entities

Ring finger protein 168 is a protein that in humans is encoded by the RNF168 gene.

Language: English [EN]
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RNF168 topic overview

The analysis highlights Overview, Related Topics and Entities as prominent areas in the source structure around RNF168.

Related topics
7
Source areas
1
Connected nodes
8
Extracted relationships
98
Concept neighborhoods
8
Bridge connections
8

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 7 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.3.2.27
Aliases
RNF168, hring finger protein 168, RIDL
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3L11, 4GB0
Band
3q29 · 16|16 B2
Bgee
sperm · tendon of biceps brachii · pancreatic epithelial cell · parietal pleura · visceral pleura
BioGPS
n/a

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How RNF168 connects Entity context

The extracted context around RNF168 shows recurring relationship patterns in the source. For example, RNF168 → cellular response to DNA damage stimulus, chromatin binding, chromatin organization, cytosol, DNA repair, double-strand break repair, double-strand break repair via nonhomologous end joining, histone binding, histone H2A K63-linked ubiquitination, histone H2A monoubiquitination, histone H2A ubiquitination, histone H2A-K13 ubiquitination, histone H2A-K15 ubiquitination, interstrand cross-link repair, isotype switching, K63-linked polyubiquitin modification-dependent protein binding, metal ion binding, negative regulation of transcription elongation from RNA polymerase II promoter, nucleoplasm, nucleosome binding Another extracted example is RNF168 → Achilles tendon, cardiac muscle tissue of right atrium, epithelium of nasopharynx, facial motor nucleus, genital tubercle, germinal epithelium, gonad, hand, otic vesicle, pancreatic epithelial cell, Paneth cell, parietal pleura, primary oocyte, secondary oocyte, sperm, substantia nigra, tail of embryo, tendon of biceps brachii, visceral pleura, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

RNF168

Top relations

Gene ontology · 33
RNF168 → cellular response to DNA damage stimulus, chromatin binding, chromatin organization, cytosol, DNA repair, double-strand break repair, double-strand break repair via nonhomologous end joining, histone binding, histone H2A K63-linked ubiquitination, histone H2A monoubiquitination, histone H2A ubiquitination, histone H2A-K13 ubiquitination, histone H2A-K15 ubiquitination, interstrand cross-link repair, isotype switching, K63-linked polyubiquitin modification-dependent protein binding, metal ion binding, negative regulation of transcription elongation from RNA polymerase II promoter, nucleoplasm, nucleosome binding
Bgee · 20
RNF168 → Achilles tendon, cardiac muscle tissue of right atrium, epithelium of nasopharynx, facial motor nucleus, genital tubercle, germinal epithelium, gonad, hand, otic vesicle, pancreatic epithelial cell, Paneth cell, parietal pleura, primary oocyte, secondary oocyte, sperm, substantia nigra, tail of embryo, tendon of biceps brachii, visceral pleura, zygote
RNA expression pattern · 20
RNF168 → Achilles tendon, cardiac muscle tissue of right atrium, epithelium of nasopharynx, facial motor nucleus, genital tubercle, germinal epithelium, gonad, hand, otic vesicle, pancreatic epithelial cell, Paneth cell, parietal pleura, primary oocyte, secondary oocyte, sperm, substantia nigra, tail of embryo, tendon of biceps brachii, visceral pleura, zygote
Band · 2
RNF168 → 16|16 B2, 3q29
Chr. · 2
RNF168 → Chromosome 16 (mouse), Chromosome 3 (human)
End · 2
RNF168 → 196,503,768 bp, 32,120,252 bp
2.3.2.27 · 1
RNF168 → ↗
Aliases · 1
RNF168 → RNF168, hring finger protein 168, RIDL
Available structures · 1
RNF168 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3L11, 4GB0
BioGPS · 1
RNF168 → n/a

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene protein bp chr human band chromosome finger location ring involved repair mouse 168 ubiquitin ligase double-strand domain search activity

RNF168 relationships Subject–Predicate–Object triples

TTTA extracted 98 structured relationships around RNF168. Examples in this analysis include RNF168 → 2.3.2.27 → ↗ and RNF168 → Aliases → RNF168, hring finger protein 168, RIDL. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
RNF1682.3.2.271.00infobox
RNF168AliasesRNF168, hring finger protein 168, RIDL1.00infobox
RNF168Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3L11, 4GB01.00infobox
RNF168Band3q291.00infobox
RNF168Band16|16 B21.00infobox
RNF168Bgeesperm1.00infobox
RNF168Bgeetendon of biceps brachii1.00infobox
RNF168Bgeepancreatic epithelial cell1.00infobox
RNF168Bgeeparietal pleura1.00infobox
RNF168Bgeevisceral pleura1.00infobox
RNF168BgeeAchilles tendon1.00infobox
RNF168Bgeeepithelium of nasopharynx1.00infobox
RNF168Bgeegerminal epithelium1.00infobox
RNF168Bgeegonad1.00infobox
RNF168Bgeecardiac muscle tissue of right atrium1.00infobox
RNF168Bgeezygote1.00infobox
RNF168Bgeesecondary oocyte1.00infobox
RNF168Bgeegenital tubercle1.00infobox
RNF168Bgeeprimary oocyte1.00infobox
RNF168BgeePaneth cell1.00infobox
RNF168Bgeehand1.00infobox
RNF168Bgeeotic vesicle1.00infobox
RNF168Bgeetail of embryo1.00infobox
RNF168Bgeesubstantia nigra1.00infobox
RNF168Bgeefacial motor nucleus1.00infobox
RNF168BioGPSn/a1.00infobox
RNF168Chr.Chromosome 3 (human)1.00infobox
RNF168Chr.Chromosome 16 (mouse)1.00infobox
RNF168DatabasesNCBI: entry; OMA: entry1.00infobox
RNF168End196,503,768 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around RNF168 bring nearby vocabulary together. In this analysis, examples include Activity, Search and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • protein
    • Rnf168
    • Gene
    • Activity
    • Domain
    • Double-strand
    • Involved
    • Ligase
    • Repair
    • Ring
    • Search
    • Ubiquitin
    • Location
  • gene
    • Protein
    • Location
    • Rnf168
    • Chromosome
    • Human
    • Bp
    • Chr
    • Activity
    • Domain
    • End
    • Ligase
    • Mouse
  • e3 ubiquitin ligase
    • Contains
    • Distinct
    • Encodes
    • Functionally
    • Known
    • Motif
    • Present
    • Proteins
    • Ubiquitin
    • Variety
    • Domain
    • Involved
  • ring finger domain
    • Ligase
    • Ubiquitin
    • Ring
    • Protein
    • Contains
    • Distinct
    • E3
    • Encodes
    • Functionally
    • Gene
    • Known
    • Motif
  • double-strand breaks
    • Repair
    • Protein
    • Activity
    • End
    • Involved
    • Ligase
    • Mouse
    • Search
    • Ubiquitin
    • Location
    • Rnf168
    • Band
  • RNF168
    • Activity
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • End
    • Mouse
    • Repair
    • Ubiquitin
    • Band
  • rnf168
    • Activity
    • Search
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • End
    • Mouse
    • Repair
    • Ubiquitin
    • Band
  • repair
    • Search
    • Ubiquitin
    • Rnf168

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the RNF168 map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

RNF168

Nodes9
Edges8
Triples98
Avg. degree1.78
Density0.222222
Components1

Source & methodology

TTTA analyzes the structure around RNF168 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Related Topics & Entities, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — RNF168 · EN edition · Analysis: TopicsToTalkAbout

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